Urinalysis in chinchillas (Chinchilla lanigera)

Doss, Grayson A.; Mans, Christoph; Houseright, Ruth A.; Webb, Julie L.

doi:10.2460/javma.248.8.901

Cited by 13 publications

(5 citation statements)

References 20 publications

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“…In our set of samples, the specific gravity values before and after centrifugation were the same, thus, they were not affected by the excreted calcium crystals. The same observation regarding specific gravity value was described in chinchillas by Doss et al (2016) and in rabbits by Ardiaca et al (2013). The alkaline pH in herbivorous exotic small mammals and a high concentration of cations (mostly calcium and magnesium) together with anions (mostly carbonates and phosphates) leads to the formation of urine crystals and may predispose them to a urolith formation (Hesse and Neiger 2009).…”

Section: Discussionsupporting

confidence: 78%

Biochemical profile of urine in guinea pigs (Cavia porcellus)

Cernochova¹,

Hundakova²,

Bardi³

et al. 2020

Vet. Med.

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Guinea pigs are common patients in veterinary clinics. Knowledge of the urine composition is necessary for the evaluation of their health. We, therefore, analysed the urine of fifty guinea pigs, thirty-two males, and eighteen females, aged between four months and seven years. None of these guinea pigs showed clinical signs of urinary tract diseases. The urine samples were obtained as part of a preventive check-up, during a regular dental check-up or another minor procedure. The urine was acquired by spontaneous micturition after inducing a short-term, light isoflurane anaesthesia. A macroscopic evaluation of the urine samples and a urine dipstick test were used for the preliminary examination. The average pH was determined to be 8.5 ± 0.5, and in three animals, moderate glycosuria was detected using the urine dipsticks. No urobilinogen, ketone bodies, haemoglobin, or blood traces were present in any of the samples. Severe proteinuria was detected in all the samples. The samples were subsequently evaluated in a laboratory for the following values: specific gravity 1 024.40 ± 1.83 kg/m<sup>3</sup>, osmolality 601.14 ± 52.28 mOsm/kg, total protein 290.16 ± 34.73 mg/l, albumin 12.04 ± 1.92 mg/l, glucose 0.77 ± 0.20 mmol/l, urea 217.60 ± 24.23 mmol/l, creatinine 3.98 ± 0.48 mmol/l, bilirubin 9.63 ± 1.73 μmol/l, calcium 6.14 ± 0.40 mmol/l, phosphorus 4.95 ± 1.30 mmol/l, magnesium 9.86 ± 0.57 mmol/l, sodium 49.15 ± 6.67 mmol/l, potassium 152.21 ± 10.62 mmol/l, chloride 51.14 ± 5.81 mmol/l, activity of gamma-glutamyltransferase 0.72 ± 0.14 μkat/l, alkaline phosphatase 0.56 ± 0.11 μkat/l and lactate dehydrogenase 0.68 ± 0.14 μkat/l. The descriptive values of the urine biochemical parameters of guinea pigs were determined for the first time in this study.

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Section: Discussionsupporting

confidence: 78%

Biochemical profile of urine in guinea pigs (Cavia porcellus)

Cernochova¹,

Hundakova²,

Bardi³

et al. 2020

Vet. Med.

View full text Add to dashboard Cite

show abstract

“…Crystalluria is common in chinchillas, but calcium carbonate crystalluria is uncommon and not considered normal (Doss et al . ) Calcium carbonate crystals were not reported in any of the animals in our study but, because most urine samples were analysed by an in‐house laboratory, it cannot be excluded that these may have been missed or the sediment may have not been analysed in all cases. Since calcium carbonate crystalluria is not considered normal in chinchillas, clinicians should consider close monitoring for future development of urolithiasis in chinchillas diagnosed with calcium carbonate crystalluria.…”

Section: Discussionmentioning

confidence: 80%

“…A study on normal urine composition in chinchillas showed that proteinuria was diagnosed in all samples examined by dipstick and that males had higher protein concentrations but, importantly, quantitative urine protein analysis did not correlate with dipstick protein levels (Doss et al . ). Therefore urine protein concentration cannot be interpreted in chinchillas based solely on dipstick testing.…”

Section: Discussionmentioning

confidence: 97%

“…Proteinuria was also a common finding in chinchillas in this study but was identified by dipstick and so these results should be interpreted cautiously. A study on normal urine composition in chinchillas showed that proteinuria was diagnosed in all samples examined by dipstick and that males had higher protein concentrations but, importantly, quantitative urine protein analysis did not correlate with dipstick protein levels (Doss et al . 2016 ).…”

Section: Discussionmentioning

confidence: 99%

“…It is currently unknown whether calcium carbonate uroliths in chinchillas occur secondary to urine supersaturation with calcium carbonate crystals. Crystalluria is common in chinchillas, but calcium carbonate crystalluria is uncommon and not considered normal (Doss et al . 2016 ) Calcium carbonate crystals were not reported in any of the animals in our study but, because most urine samples were analysed by an in-house laboratory, it cannot be excluded that these may have been missed or the sediment may have not been analysed in all cases.…”

Section: Discussionmentioning

confidence: 99%

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