The role of metabolic state and obestatin in control of chicken ovarian hormone release

Abstract

The aim of the present study was to examine the role and interrelationships between calorie restriction and obestatin in the control of hormone release by chicken ovarian tissue. For this purpose, we compared the release of progesterone (P), testosteron (T), estradiol (E), and arginine-vasotocin (AVT) by ovarian fragments isolated from chicken subjected and not subjested to food restriction, as well as the response of these ovarian fragments to obestatin additions.It was observed that food restriction promoted release of P, reduced output of T, but did not affect basal E and AVT release. Obestatin addition reduced E, promoted AVT, and did not alter P and T release by ovarian tissue isolated from ad libitum fed chicken. In ovarian fragments of fasted hens it reduced E, promoted T, and did not influence P and AVT release.The present observations demonstrate (1) that obestatin can directly control the release of avian ovarian hormones - regulators of reproduction, (2) that metabolic state can control the release of these hormones, and (3) metabolic state can alter the response of ovarian hormones to obestatin.

Interacting Networks of the Hypothalamic–Pituitary–Ovarian Axis Regulate Layer Hens Performance

“…Nutrition affects the secretion of reproductive hormones and the concentration of metabolic substrates in blood. Research showed that food restriction promoted release of P4, reduced out of the T, but did not affect E release, suggesting that metabolic status can control the release of these hormones [32]. The estrogen estradiol-17ß is known as one of the major gonadal steroid hormones with different functions in reproduction [33].…”

REPRODUCTIVE FUNCTION IN HYBRID POULTRY. IV. AN IMPACT OF MATERNAL HORMONES ACCUMULATED IN EGG (review)

“…Feeding quails with a seed mixture instead of the usual mixed feed causes an increase in HPCA activity and corticosterone response [96]. As a result of limited feeding, ovarian tissue of hens excreted in vitro more progesterone and less testosterone while secretion of 17β-estradiol and arginine vasotocin did not change [97]. In the hypothalamus and ovary of 23-week-old individuals, expression of grehlin and its receptors was activated.…”