Efecto de la crisis económica sobre el consumo de psicofármacos en Asturias

Nicieza-García, María Luisa; Alonso-Lorenzo, Julio C.; Suárez-Gil, Patricio; Rilla-Villar, Natalia

doi:10.1016/j.gaceta.2016.02.006

Cited by 10 publications

(4 citation statements)

References 6 publications

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“…However, we observed no changes in trend consistent with this hypothesis. This result is consistent with those of studies in Paterna [ 33 ] and Asturias [ 29 ]. In fact, the only change observed was in March 2009, when the MPC of overall DID decreased from 0.4 to 0.1%.…”

Section: Discussionsupporting

confidence: 94%

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Analysis of changes in trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs

García

Lima

López³

et al. 2018

J of Pharm Policy and Pract

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BackgroundTo analyse trends in the rates of consumption of benzodiazepine (BZD) anxiolytics, BZD hypnotics and non-BZD hypnotics and the association with contextual factors.MethodsDescriptive time series study. Units of analysis were monthly dose per inhabitant per day (DID) and dose per medical card per day(DCD) of benzodiazepine(BZD anxiolytics(BZD-A), BZD hypnotics(BZD-H) and non-BZD hypnotics(Non-BZD-H) between January 2006-December 2015. We analysed 6 primary healthcare districts(PHD) and used defined daily doses (DDDs) to calculate the monthly DIDs(overall and by ATC group). Trends and monthly percentage change (MPC) were analysed through joinpoint regression.ResultsThe annual DID increased by 26% overall, the trend was different across ATC groups. Consumption in BZD-A and BZD-H increased (27.1%,61.9%), consumption in Non-BZD-H decreased by 35%. There was high variability in DCD across the PHD, with an overall increase of 10.2%(5.7%-22.9%). By ATC, DCD increased by 10.4% in BZD-A(4.2%-22.2%) and by 44.2% in BZD-H(33.2%-76.5%). The overall DCD in the Non-BZD-H decreased by 42.1%(19.7%-50.8%). We found an initial upward trend in consumption of BZD-A until April/2008(monthly percentage change –MPC- +0.5%), followed by a slightly slower increase (+0.1%). No changes in trend were detected in BZD-H. In Non-BZD-H, we observed an upward trend until February/2013(+0.1%), followed by a sharp decrease until August/2013(−6.3%), and finally a slight decrease(−0.3%).ConclusionsBZD consumption has increased in the last decade, with variability across areas. The changes in trends do not coincide with the financial crisis, introduction of prescriptions by active ingredient, electronic prescriptions or copayment. The only decrease in the Non-BZD-H may be linked to an intervention.

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Section: Discussionsupporting

confidence: 94%

“…Both DIDs hit around 89 in 2012, and continued to increase in all subgroups. A study in Asturias had almost identical results [ 29 ]. Because we do not have the updated national data, we do not know if the Non-BZD-H group followed the same downward trend nationally as found in Seville from 2013 onwards.…”

Section: Discussionmentioning

confidence: 86%

Analysis of changes in trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs

García

Lima

López³

et al. 2018

J of Pharm Policy and Pract

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“…Like our study, Colell et al ,28 did not find significant changes in the sporadic use of hypnotics/sedatives for men or women (regardless of employment status) before and during a financial crisis either, nor did Nicieza-García et al 45 confirm that the rise in psychotropic medication consumption in the region of Asturias was a result of the financial crisis. However, our results differ from other similar studies.…”

Section: Discussionsupporting

confidence: 59%

Did psychotropic drug consumption increase during the 2008 financial crisis? A cross-sectional population-based study in Spain

et al. 2019

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Objectives and settingAlthough psychotropic drugs are used to treat mental health disorders, little evidence analyses the effects the 2008 economic downturn had on psychotropic drug consumption in the case of Spain. We analyse these effects, considering both gender and employment situation.ParticipantsWe used the microdata from the face-to-face cross-sectional population-based Spanish National Health Survey for two periods: 2006–2007 (n=28 954) and 2011–2012 (n=20 509). Our samples included adults (>15 years old).MethodsThe response variables are consumption (or not) of antidepressants or sedatives and the explanatory variables are the year of the survey, gender and employment status. Covariates are mental health problems, mental health index General Health Questionnaire (GHQ-12) and self-reported health outcome variables such as self-rated health, chronic diseases, smoking behaviour, sleeping hours, body mass index, physical activity in the workplace, medical visits during the past year, age, region of residence (autonomous communities), educational level, marital status and social class of the reference person. Finally, we include interactions between time period, gender and employment status. We specify random effects logistic regressions and use Bayesian methods for the inference.ResultsThe economic crisis did not significantly change the probability of taking antidepressant drugs (OR=0.56, 95% CI 0.18 to 2.56) nor sedatives (OR=1.21, 95% CI 0.26 to 5.49). In general, the probability of consuming antidepressants among men and women decreases, but there are differences depending on employment status. The probability of consuming sedatives also depends on the employment status.ConclusionsWhile the year of the financial crisis is not associated with the consumption of antidepressants nor sedatives, it has widened the gap in consumption differences between men and women. Although antidepressant use dropped, the difference in consumption levels between men and women grew significantly among the retired, and in the case of sedatives, risk of women taking sedatives increased in all groups except students.

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“…However, an isolated study in southern Spain showed an increase in benzodiazepine prescriptions (26%) between 2006 and 2015, but this study had high variability between areas [30]. A different study in Asturias (northern Spain) found an increasing rate of use between the period from point A (2003)(2004)(2005)(2006)(2007)(2008) to point B (2009-Do not disseminate or use without explicit permission from the authors 15 2013) of 32% for anxiolytic drugs and 74% for hypnotic drugs for all of Spain, 7.9% and 5.9%, respectively [31]. These data suggest that any conclusions drawn from these studies should be made cautiously because of the regional differences between the studies.…”

Section: Discussionmentioning

confidence: 99%

Call for Action: Benzodiazepine Prescription Prevalence Analysis Shows Off-Label Prescription in One in Eleven Citizens

López‐Pelayo

Coma²,

Gual

et al. 2019

Eur Addict Res

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Objective: Benzodiazepines have a good safety profile. Nevertheless, off-label use of these drugs may increase the risk of falls, dependence, and memory loss. Off-label prescription use is not highly prevalent. Studies have not researched the factors that influence off-label prescription use. We aim to identify the prevalence of off-label use of benzodiazepines in Barcelona and explore socio-demographic factors that may be involved for professionals and patients. Method:A cross-sectional study in Barcelona was carried out. Data from professionals were obtained from the Medical Official College of Barcelona. Patients' healthcare data were extracted from the electronic prescription system DataMart and from the Catalan Health System Observatory (catchment of 97% of the prescription system).Two multivariate analyses were performed to identify risk factors of off-label prescription use; one focused on the patients' characteristics and the other focused on professionals' characteristics.Results: 9.7% of Barcelona's citizens used benzodiazepine prescriptions; 96.1% of them were off-label uses. The most common reason was long-term use (95.8%). Elderly patients were the most common demographic that was exposed to off-label use (OR = Do not disseminate or use without explicit permission from the authors 2 1.05, CI95% = 1.04-1.05). Family doctors (B= 38.87,) andpsychiatrists (B = 16.93; were the largest groups of off-label prescribers.Conclusions: The prevalence of benzodiazepine off-label prescriptions in our environment is very high, especially when the length of the treatment is considered.Implementation of evidenced-based strategies to facilitate more effective prescription practices is required.

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Efecto de la crisis económica sobre el consumo de psicofármacos en Asturias

Abstract: The rise in consumption of the three subgroups during the crisis period was lower than that of the pre-crisis period. This study does not confirm the influence of the economic crisis on the rise in consumption of these drugs.

Cited by 10 publications

References 6 publications

Analysis of changes in trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs

Analysis of changes in trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs

Did psychotropic drug consumption increase during the 2008 financial crisis? A cross-sectional population-based study in Spain

Call for Action: Benzodiazepine Prescription Prevalence Analysis Shows Off-Label Prescription in One in Eleven Citizens

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