Solitary ﬁbrous tumor of the salivary gland: A case report

Zhou, Yingwen; Zheng, Jing; Zhu, Qi; Bhagat, Santosh Kumar

doi:10.3892/ol.2015.3948

Cited by 5 publications

(7 citation statements)

References 18 publications

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“…In recent years this tumor has been documented in almost every anatomic location. In the head and neck region, SFT may be found in the orbit, nose and paranasal sinuses, major salivary glands, larynx, thyroid, and the deep soft tissues of the neck, among other places [ 3 , 4 , 5 , 6 , 7 , 8 ]. Oral SFT is a rare entity—only 150 cases were reported until May 2019, and most were case reports with only a few case series.…”

Section: Introductionmentioning

confidence: 99%

Oral Solitary Fibrous Tumor: A Retrospective Clinico-Pathological Study and Long-Term Follow-Up

et al. 2021

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Background and Objectives: This was a retrospective single-center study to analyze and describe the clinical and histological features of all cases of oral solitary fibrous tumor (SFT). Study design: the study included all consecutive cases of oral SFT diagnosed between 2008–2018 at a single tertiary center. Materials and Methods: Clinical data was retrieved from medical charts. The diagnosis of oral SFT was based upon the morphologic features of the lesions, in routine hematoxylin and eosin (H&E) stained sections and confirmed by immunohistochemical analyses including CD34, CD99, Bcl2, and stains for STAT6. Results: Seven cases of oral SFT were found. Of these, three (42%) were in males and four (58%) in females. The age range was 24–63 years (mean 47 ± 13). Four (58%) lesions were located in the buccal mucosa, two (28%) in the labial mucosa and one (14%) on the floor of the mouth. The diameter ranged between 3–50 mm (mean 22 ± 14 mm). All patients were treated with local excision. Follow-up periods were between 2–74 months (mean 41 ± 27). No recurrences were reported. Conclusions: We present a series of oral SFT, which were all non-aggressive in presentation and did not recur after conservative surgery (local excision) over a relatively long follow-up period.

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Section: Introductionmentioning

confidence: 99%

Oral Solitary Fibrous Tumor: A Retrospective Clinico-Pathological Study and Long-Term Follow-Up

et al. 2021

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“…Involvement of unusual sites such as the oral and maxillofacial region has been reported in the literature [2–5]. …”

Section: Introductionmentioning

confidence: 99%

“…Solitary fibrous tumor (SFT) is a rare neoplasm of mesenchymal origin that usually affects the pleura [ 1 ]. Involvement of unusual sites such as the oral and maxillofacial region has been reported in the literature [ 2 – 5 ].…”

Section: Introductionmentioning

confidence: 99%

An Unusual Clinical Presentation of Solitary Fibrous Tumor in the Oral Cavity

Morais

Moreira

Oliveira

et al. 2017

Case Reports in Pathology

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Solitary fibrous tumor is a rare neoplasm of mesenchymal origin that usually affects the pleura. This rarity becomes more relevant in the oral cavity since the clinical features are nonspecific. A 66-year-old female patient presented with a 3-month history of a swelling in the floor of the mouth, measuring 2 cm in greatest diameter, and pain symptomatology. Occlusal and panoramic radiographs showed no bone involvement. Ultrasonography of the submandibular and parotid salivary glands revealed normal morphology, dimensions, and echogenicity. During this exam, a nodular image of low echogenicity measuring about 2.7 × 1.8 cm was detected. An excisional biopsy was performed and histopathological analysis revealed a well-defined tumor-like lesion with alternation between hypercellular areas without a defined pattern and hypocellular areas. On immunohistochemistry, the tumor was positive for CD34 and CD99 and negative for α-SMA, S-100, and bcl-2. Combining the histopathological and immunohistochemical features, the diagnosis was solitary fibrous tumor. The patient is under periodical clinical follow-up and shows no signs of recurrence 7 months after surgical excision of the tumor. The combination of clinical-pathological and immunohistochemical features is necessary for the diagnosis.

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“…Giant refractory thoracic tumors of various pathological types invade the surrounding tissues and organs with serious consequences. Moreover, completely removing tumors using conventional thoracic surgery is difficult, resulting in poor patient prognosis 1–4 . The surgical strategy for complete tumor resection is also extremely high‐risk, but the adoption of cardiopulmonary bypass (CPB) can ensure the stability of intraoperative respiratory circulation and create favorable conditions for complete tumor resection 5 .…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, completely removing tumors using conventional thoracic surgery is difficult, resulting in poor patient prognosis. 1 , 2 , 3 , 4 The surgical strategy for complete tumor resection is also extremely high‐risk, but the adoption of cardiopulmonary bypass (CPB) can ensure the stability of intraoperative respiratory circulation and create favorable conditions for complete tumor resection. 5 Surgeons have been reluctant to use CPB during surgery due to the many complications associated with the procedure and the possibility that it may promote distant metastasis of tumor cells.…”

Section: Introductionmentioning

confidence: 99%

Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up

Chen

Zhu

et al. 2021

Thoracic Cancer

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Background Few clinical research studies with long‐term follow‐up have revealed whether cardiopulmonary bypass (CPB) increases the risk of postoperative distant metastasis in patients with giant refractory thoracic tumors. The present study evaluated the risk of distant metastasis after surgery utilizing CPB with long‐term follow‐up. Methods Clinical data for patients with giant refractory thoracic tumors who underwent resection with the use of CPB in the Second Affiliated Hospital of Soochow University during the past 11 years were retrospectively reviewed. Results Of the 14 patients with giant refractory thoracic tumors who had undergone surgery under CPB, 10 patients (71.4%) were completely resected. Twelve patients were followed up for 13–127 months with 10 patients were completely resected and two patients could not be completely resected due to severe tissue invasion. Three patients (25%) suffered from distant metastasis, and four patients (33.3%) experienced local recurrence. Only one patient (1/10) with complete resection suffered from distant metastasis, while two patients (2/10) experienced local recurrence. Two patients (2/2) with major resection suffered from both distant metastasis and local recurrence. Median overall survival for patients who have been regularly followed up was 50 months with 1‐, 5‐, and 10‐year survival of 100%, 75%, and 66.7%. No difference was found between the distant metastasis survival and the local recurrence survival. (p = 0.99). Conclusions CPB is an effective strategy for complete resection of the giant refractory thoracic tumors with an acceptable risk of postoperative distant metastasis for some patients.

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Solitary ﬁbrous tumor of the salivary gland: A case report

Cited by 5 publications

References 18 publications

Oral Solitary Fibrous Tumor: A Retrospective Clinico-Pathological Study and Long-Term Follow-Up

Oral Solitary Fibrous Tumor: A Retrospective Clinico-Pathological Study and Long-Term Follow-Up

An Unusual Clinical Presentation of Solitary Fibrous Tumor in the Oral Cavity

Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up

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