Evaluation of Quality of Life, Functioning, Disability, and Work/School Productivity Following Treatment with an Extended‐Release Hydrocodone Tablet Formulated with Abuse‐Deterrence Technology: A 12‐month Open‐label Study in Patients with Chronic Pain

Hale, M.; Zimmerman, Thomas; Ma, Yuju; Malamut, Richard

doi:10.1111/papr.12433

Cited by 3 publications

(2 citation statements)

References 22 publications

(31 reference statements)

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“…For this reason, practitioners may need assistance from drug addiction psychiatrists. Unfortunately urgent appointments for these types of assessments are very difficult to arrange impacting assessment and management [1,6,16]. To address these concerns we have developed a system suitable for Academic Centers that takes advantage of existing resources.…”

Section: Introductionmentioning

confidence: 99%

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Evaluating the Risk of Opioid Abuse in Chronic Pain Patients by Addiction Psychiatry Fellows in an Academic Pain Center

Cruciani¹

2016

JOJCS

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Context: Assessing risk of abuse plays an important role in deciding to prescribe opioids for the management of chronic pain.Objective: This study was designed to assess feasibility and effectiveness of opioid prescribing risk assessment by addiction psychiatry fellows during their rotation in a pain clinic in an academic center. Methods:A total of 202 chronic pain patients were evaluated for opioid prescribing risk. Seven addiction psychiatry fellows evaluated opioid prescribing risk in chronic pain patients during their rotation in the pain clinic required as part of their training. One-time patient evaluations for opioid abuse risk were conducted in a once a week ½ day clinic pain clinic. Patient demographics, diagnoses, treatment course, and recommendations were prospectively collected. The main outcome of this study was to determine the number of patients at a high-risk for opioid abuse who were identified as a result of this program. Results:Abnormal toxicology results and high-risk for opioid prescribing was found in 128 patients. Of patients referred for consultation, only 2% were recommended for continued opioid therapy. Conclusion:This feasibility study suggests that supervised addiction psychiatric fellows can conduct opioid prescribing risk assessment effectively. This additional level of assessment was requested by less experienced practitioners, like fellows, while seasoned attending physicians were less inclined to request assistance. Larger multicenter studies are needed to confirm these findings.

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Section: Introductionmentioning

confidence: 99%

“…Historically, opioids have played a crucial role in the management of pain [1][2][3]. However, long-term opioid therapy is now controversial due to reports of increases in accidental deaths associated with prescription opioids [4].…”

Section: Introductionmentioning

confidence: 99%

Evaluating the Risk of Opioid Abuse in Chronic Pain Patients by Addiction Psychiatry Fellows in an Academic Pain Center

Cruciani¹

2016

JOJCS

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The prescription opioid conundrum: 21st century solutions to a millennia-long problem

Brennan¹,

Gudin

2019

Postgraduate Medicine

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Cognitive impact of chronic opioid use: A systematic review

Macedo Soares,

Estrin

2023

SCT Proceedings in Interdisciplinary Insights and Innovations

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Background: The impact of chronic opioid use has been linked to a wide range of cognitive disorders, ranging from minor deficits in cognitive abilities such as attention, learning, memory and executive functions. The objective of this work is to carry out a systematic review to investigate the cognitive impact in patients who chronically use opioids and to evaluate the severity of this impact. Material and methods: Randomized clinical trials, case-control studies, prospective and retrospective cohorts werw evaluated in two databases: PubMed and Cochrane Central. The search in english, spanish and portuguese languages of stududies carried out in adult humans an chronic use of opioids and their cognitive impact. Results: 7 studies were selected, 5 of wich the patients used Tramadol and the negative cognitive impact was verified, 1 study with the use of Tapentadol with a positive impact on cognition and 1 study with the use of Hydrocodone with a positive impact on neurocognition of the patients. Conclusion: (In conclusion, despite the limitations found here, we consider that tramadol has a negative impact on neurocognition, which does not occur in relation to tapentadol and hydrocodone, which presents an improvement in the quality of life and cognition of patients

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Evaluation of Quality of Life, Functioning, Disability, and Work/School Productivity Following Treatment with an Extended‐Release Hydrocodone Tablet Formulated with Abuse‐Deterrence Technology: A 12‐month Open‐label Study in Patients with Chronic Pain

Abstract: Patients receiving hydrocodone ER showed early numeric improvements in functioning that continued throughout this 12-month study.

Cited by 3 publications

References 22 publications

Evaluating the Risk of Opioid Abuse in Chronic Pain Patients by Addiction Psychiatry Fellows in an Academic Pain Center

Evaluating the Risk of Opioid Abuse in Chronic Pain Patients by Addiction Psychiatry Fellows in an Academic Pain Center

The prescription opioid conundrum: 21st century solutions to a millennia-long problem

Cognitive impact of chronic opioid use: A systematic review

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