Electrically evoked compound action potential (ECAP) in cochlear implant children: Changes in auditory nerve response in first year of cochlear implant use

Telmesani, Laila M.; Said, Nithreen M.

doi:10.1016/j.ijporl.2015.12.027

Cited by 28 publications

(15 citation statements)

References 20 publications

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“…Stronks, Versnel, Prijs, Grolman, & Klis () have also reported that, compared with normal‐hearing animals, the suppression of CAP induced by intracochlear electrical stimulation was significantly less in animals with high‐frequency hearing loss. This can, to some extent, explain the discrepancy between the clinical trials mentioned above (Brown et al, ; Coco et al, ; Telmesani & Said, ) and our present study. The findings observed in the present research were based on acute electrical stimulation.…”

Section: Discussioncontrasting

confidence: 77%

“…Notably, different findings were reported by a few clinical trials in human subjects. Several articles have demonstrated that no change was observed for ECAP threshold after long‐term use of CI (Coco et al, ; Telmesani & Said, ), or even if there were changes, the magnitude of changes was small in view of the long observation interval (Brown, Abbas, Etlert, O'Brient, & Oleson, ), suggesting that electrical stimulation has no significant adverse effect on the response of auditory nerve. It should be noted that the auditory nerve states of the subjects in their studies were abnormal to varying degrees, whereas the functional states of the auditory nerve in our study were normal.…”

Section: Discussionmentioning

confidence: 99%

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Electrical stimulation induces synaptic changes in the peripheral auditory system

Zhang

et al. 2019

J of Comparative Neurology

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Since a rapidly increasing number of neurostimulation devices are used clinically to modulate specific neural functions, the impact of electrical stimulation on targeted neural structure and function has become a key issue. In particular, the specific effect of electrical stimulation via a cochlear implant (CI) on inner hair cell (IHC) synapses remains unclear. Importantly, CI candidacy has recently expanded to include patients with partial hearing loss. Unfortunately, some CI recipients experience progressive hearing loss after activation of electrical stimulation. The mechanism(s) accounting for loss of residual hearing following electrical stimulation is unknown. Here normalhearing guinea pigs were implanted with customized CIs. Intracochlear electrical stimulation with an intensity equal to or above electrically evoked compound action potential (ECAP) threshold decreased the excitability of auditory nerve. Furthermore, the number of synapses between IHCs and the afferent spiral ganglion neurons (SGNs) also decreased after electrical stimulation with higher intensities. However, no significant change was observed in the packing density and perikaryal area of SGNs as well as the quantity of hair cells. These results carry important implications for use of CIs in patients with residual hearing and for an increasing number of patients treated with other neurostimulation devices. Notably, the results were based on acute electrical stimulation. Considering the complex interaction between CIs and targeted tissues, it is urgent to conduct further research to clarify whether the similar changes could be induced by chronic electrical stimulation.

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Section: Discussioncontrasting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Electrical stimulation induces synaptic changes in the peripheral auditory system

Zhang

et al. 2019

J of Comparative Neurology

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“…First, intraoperative ECAP thresholds showed correlations with the BCNC width and CSV of the CN in some electrodes (electrodes 1, 4 and 6). This may be non‐specific because ECAP thresholds were high intraoperatively and decreased significantly after fitting of the implant . Second, MAP data were relevant only to the CSV of the CN and not to BCNC width.…”

Section: Discussionmentioning

confidence: 99%

Can radiological measurements of cochlear nerve parameters predict cochlear implant outcome? Our experience in 87 ears

Jang

Kim

Mun

et al. 2019

Clinical Otolaryngology

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“…Порог ECAP используется чаще всего для настройки речевого процессора, особенно у детей с ограниченным слуховым опытом. [24].…”

Section: телеметрия нервного ответаunclassified

Кохлеарная Имплантация У Новорожденных: Сложности И Особенности

Егоров¹,

Глуховский²

2021

Естественные И Технические Науки

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Потеря слуха по тем или иным причинам всегда невосполнимая утрата, а в отношении ребёнка -это ещё и табу на адекватную социализацию и полноценное развитие талантов ребенка. Слух -это не только сенсорная составляющая функционирования человеческого организма, это пусковой механизм развития коммуникационных способностей, а значит социализации человека в обществе.На сегодняшний день метод кохлеарной имплантации -это единственный способ реабилитации людей, столкнувшихся с потерей слуха, в частности детей с глубокой нейросенсорной тугоухостью, а значит -интеграции их в социально активную жизнь.

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Electrically evoked compound action potential (ECAP) in cochlear implant children: Changes in auditory nerve response in first year of cochlear implant use

Cited by 28 publications

References 20 publications

Electrical stimulation induces synaptic changes in the peripheral auditory system

Electrical stimulation induces synaptic changes in the peripheral auditory system

Can radiological measurements of cochlear nerve parameters predict cochlear implant outcome? Our experience in 87 ears

Кохлеарная Имплантация У Новорожденных: Сложности И Особенности

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