The D9N, N291S, and T495G Polymorphisms of the Lipoprotein Lipase Gene Are Not Associated with Cerebral Infarction

The HindIII and PvuII polymorphisms of lipoprotein lipase (LPL) gene reduce the risk of ischemic stroke (IS)

“…[22] However, Xu et al showed discouraging results. [26] Our combined analysis demonstrated that the dominant model of PvuII (+/−) was significantly related to the IS risk in Asian. And the recessive model of PvuII (+/−) was significantly related to IS risk in Caucasian.…”

“…[22] For HindIII (+/−), several studies have shown significant association between HindIII (−) and IS. [25,26] However, no association was reported by Huang et al and Xu et al [27,28] As for PvuII (+/−), Xu et al have suggested that PvuII (+/−) polymorphism was associated with lipid profile and IS. [28] However, other 2 studies reported no genetic association between PvuII (+/−) and IS.…”

Logic Regression Analysis of Gene Polymorphisms and HDL Levels in a Nationally Representative Sample of Iranian Adolescents: The CASPIAN-III Study

“…It was reported that rs1801177 polymorphism affects serum lipids, and thus increase the CVD risk (54). However, another case–control study showed that the rs1801177 genotype was not significantly correlated with CVD (55).…”