Maternal Dietary Patterns are Associated with Lower Levels of Cardiometabolic Markers during Pregnancy

Abstract

Background-Elevated levels of cardiometabolic markers are characteristic of normal pregnancy; however, insulin resistance and increased glucose, triglyceride, and cholesterol levels can adversely influence maternal and child health. Diet is a modifiable behavior that could have significant impact on maternal cardiometabolic levels during pregnancy. We investigated the association between dietary patterns and cardiometabolic markers (glucose, insulin, insulin resistance (HOMA-IR), triglycerides, and cholesterol) during pregnancy.

1H NMR-based metabolomics reveals the effect of maternal habitual dietary patterns on human amniotic fluid profile

“…The present study showed that this expected increase in maternal lipids was, further, promoted in women of C2, whose dietary preferences were associated with higher total lipid, monounsaturated and polyunsaturated fatty acids intakes, compared to C1. It is of interest to mention that in a very recent study 61 , higher blood total cholesterol levels were recorded in pregnant women following a dietary pattern characterized, among others, by higher intakes of fruits, vegetables, whole grains, and low-fat dairy. However, due to the strong influence of pre-pregnancy lipid levels and maternal hormonal status during pregnancy on lipid metabolism 59 , 62 , no clear biochemical interpretation may be advanced at least at this stage.…”

Determinants of dietary patterns and diet quality during pregnancy: a systematic review with narrative synthesis

“…fetal growth, preterm birth and risk of asthma) ( 14 ) . Likewise DQ was associated with blood TAG ( 15 ) , pre-eclampsia ( 16 ) and fetal growth restriction ( 17 ) .…”

Reference Intervals for Non-Fasting CVD Lipids and Inflammation Markers in Pregnant Indigenous Australian Women

“…Dietary patterns prior to and during pregnancy have also been shown to influence levels of serum lipids [ 28 , 29 ]. In particular, dietary patterns prior to pregnancy with relatively high intakes of discretionary foods such as cakes, snacks and candies, have been demonstrated to raise triglyceride levels, particularly in the second trimester [ 28 ].…”

“…In particular, dietary patterns prior to pregnancy with relatively high intakes of discretionary foods such as cakes, snacks and candies, have been demonstrated to raise triglyceride levels, particularly in the second trimester [ 28 ]. Conversely, dietary patterns consistent with recommendations for following a DASH-type diet have shown negative associations with serum triglycerides [ 29 ]. DASH-type diets are characterized by high intakes of plant-based foods such as fruits and vegetables, and limited intakes of saturated fats and discretionary food choices [ 30 ].…”