Endoscopic ultrasound in the diagnosis and management of carcinoma pancreas

Puri, Rajesh; Manrai, Manish; Thandassery, Ragesh B.; Alfadda, Abdulrahman

doi:10.4253/wjge.v8.i2.67

Cited by 4 publications

(6 citation statements)

References 85 publications

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“…EUS seems to be the most sensitive method for diagnosing (excluding) ductal adenocarcinoma of the pancreas [ 65 ]. The high resolution of the method can visualize pancreatic lesions as small as 5 to 15 mm [ 66 ].…”

Section: Diagnostic Endoscopic Ultrasoundmentioning

confidence: 99%

Present status and perspectives of endosonography 2017 in gastroenterology

Hocke

Braden

Jenssen³

et al. 2018

Korean J Intern Med

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Endoscopic ultrasound has become an essential tool in modern gastroenterology and abdominal surgery. Compared with all other endoscopic methods, it has the most potential for innovation and its future looks bright. Thus, we compiled this summary of established and novel applications of endoscopic ultrasound methods to inform the reader about what is already possible and where future developments will lead in improving patient care further. This review is structured in four parts. The first section reports on developments in diagnostic endoscopic ultrasound, the second looks at semi-invasive endoscopic ultrasound, and the third discusses advances in therapeutic endoscopic ultrasound. An overview on the future prospects of endoscopic ultrasound methods concludes this article.

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Section: Diagnostic Endoscopic Ultrasoundmentioning

confidence: 99%

Present status and perspectives of endosonography 2017 in gastroenterology

Hocke

Braden

Jenssen³

et al. 2018

Korean J Intern Med

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“…Die Sonografie und die Endosonografie (EUS) ergänzen die konventionellen Verfahren. Mittels EUS können Läsionen bis zu 20 mm mit einer Sensitivität von 93 -100 % dargestellt werden [7,8]. Ein weiterer Vorteil der EUS im Vergleich zum CT ist, dass Lymphknotenmetastasen sowie Gefäßinfiltration mit einer höheren Sensitivität nachgewiesen werden können.…”

Section: Introductionunclassified

Kurz- und Langzeitergebnisse bei operablen duktalen Pankreasadenokarzinomen aus der Kooperation zwischen zwei Abteilungen Gastroenterologie-Viszeralchirurgie an nicht universitären Kliniken im Vergleich mit Resultaten aus Spitzenzentren

et al. 2016

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The only curative approach in pancreatic ductal adenocarcinoma (PDAC) is resection, which is possible only in 15 - 30 % of patients. Local tumor spread or distant metastases are contraindications for resection in the majority of patients. Surgical-oncological quality with short- and long-term results are varying tremendously, so that "expertise/quality" are associated to hospital- or surgeon's volume and/or center formation. The treatment results also depend, to a great extent, on the medical diagnostic quality. With our retrospective study, we aim to compare the results-quality of cooperative pancreatic cancer treatment based on an extensive preoperative diagnostic procedure for staging and risk estimation in a specialized GI-medical department and visceral surgical-oncological expertise in pancreatic cancer surgery at a general hospital with the results-quality of expert centers. Fifty-three patients with PDAC had diagnosis and resection of their cancer between 1/2002 and 12/2009. The 30 day hospital-mortality was 3.8 % and the median survival time after demission from the hospital was 23.1 months. The 5-year-survival rate of R0-resected patients, all of whom had received adjuvant chemotherapy, was high with 31 %. The survival data and the extraordinarily high resection rate of 98.1 % in the patient group, whose primary tumor stage was pT3 in 81 %, reflects the excellent cooperation of high standards in medical diagnostic processes, visceral pancreatic surgery, and adjuvant medical chemotherapy. The results are well comparable to those of "high volume centers". The responsible heads of the two departments have been trained at university expert centers. Expertise in the treatment of pancreatic cancer patients may be successfully transferred from an expert center to a general hospital, if the team has high expertise.

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“…7 Given the lengthier perfusion duration, CEH-EUS performs real-time vessel imaging of pancreatic lesions without Doppler-related artifacts. 10,11 Napoleon et al 12 performed a pilot study in 35 patients with SPL using SonoVue ® with a novel Olympus echoendoscope able to detect extended harmonics (XGF-UCT 180; Olympus America, Melville, NY, USA). 12,13 Of the 18 fine-needle aspiration (FNA)-confirmed ductal adenocarcinomas, 16 resulted in a hypointense signal on CEH-EUS.…”

Section: Contrast-enhanced Harmonic Eusmentioning

confidence: 99%

“…7,8 Contrast-enhanced Doppler EUS, however, remains limited in use secondary to blooming artifacts and lower sensitivity in vessels with low blood flow. 7,9,10 To overcome these limitations, a new generation of intravenous contrast agents, such as SonoVue ® and Echogen ® , which use gas-containing micro bubbles encapsulated by albumin or a phospholipid that oscillate in response to sound pressure, have been developed. 7 Given the lengthier perfusion duration, CEH-EUS performs real-time vessel imaging of pancreatic lesions without Doppler-related artifacts.…”

Section: Contrast-enhanced Harmonic Eusmentioning

confidence: 99%

“…CPN is attained via injection of alcohol or phenol into the celiac plexus, resulting in chemical ablation of the visceral afferent nociceptors. 3,4,10 Celiac plexus block (CPB) employs the injection of triamcinolone in combination with a local anesthetic to inhibit the transmission of pain. 4 CPN had primarily been performed via percutaneous approach involving blind needle puncture.…”

Section: Eus-guided Anastomosismentioning

confidence: 99%

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