2016
DOI: 10.2188/jea.je20150134
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Higher Body Mass Index and Increased Prevalence of Paranasal Sinus Disease

Abstract: BackgroundWe hypothesized that higher body mass index (BMI) was associated with increased prevalence of paranasal sinus disease and examined the hypothesis in Japanese adults.MethodsThis was a cross-sectional study including 1350 Japanese adults aged 40 years or more who participated in a health check-up program focusing on brain diseases and metabolic syndrome. Participants were divided into quartiles of BMI levels. Paranasal sinus disease was confirmed by a head MRI scan. The association between BMI and para… Show more

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Cited by 15 publications
(20 citation statements)
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“…By studying the relation between nasal polyps and BMI, where the mean was 30.5, there was a strong statistical relation between the increase in BMI and the incidence of nasal polyps in our study , and this was consistent with the study of (Kabeya Y, Kato K, co-authors) (4).…”
Section: Discussionsupporting
confidence: 92%
“…By studying the relation between nasal polyps and BMI, where the mean was 30.5, there was a strong statistical relation between the increase in BMI and the incidence of nasal polyps in our study , and this was consistent with the study of (Kabeya Y, Kato K, co-authors) (4).…”
Section: Discussionsupporting
confidence: 92%
“…103 A cross-sectional, large-scale study on a group of Japanese adults revealed significant, positive association between high BMI and the frequency of paranasal sinuses disease (PSD). 113 The authors established that obesity and PSD were not actually mediated by inflammation but rather by airway structural problems related to obesity or obesity-related lifestyles. They suggested that increased blood glucose levels in obese could predispose to PSD by inducing improper immune function or improper ciliary motility.…”
Section: Resultsmentioning
confidence: 99%
“…They suggested that increased blood glucose levels in obese could predispose to PSD by inducing improper immune function or improper ciliary motility. 113 Nevertheless, the certain mechanisms linking these disorders have not been established yet.…”
Section: Rhinosinusitismentioning
confidence: 99%
“…20 Additionally, allergy and high BMI, typically associated in the literature with increased sinusitis morbidity and prevalence, respectively, also showed no significant relation to high-acuity visits. 19, 21 We posit that increased morbidity and prevalence may not be directly related to high-acuity setting presentation but rather that a lack of access to routine outpatient management may cause increased presentation to the ED and inpatient setting instead.…”
Section: Discussionmentioning
confidence: 99%
“…16,17 Specific comorbid conditions (CMCs), including gastroesophageal reflux disease (GERD) and high body mass index (BMI), have been associated with an increased prevalence of sinus disease. 18,19 Depression as a CMC has also been linked with impaired health care utilization for sinusitis. 20 Additionally, comorbid allergy has been associated with increased morbidity in sinusitis.…”
Section: Introductionmentioning
confidence: 99%