Persistent postsurgical pain after video‐assisted thoracic surgery – an observational study

Wildgaard, Kim; Ringsted, Thomas K.; Hansen, Henrik Jessen; Petersen, René Horsleben; Kehlet, Henrik

doi:10.1111/aas.12681

Cited by 63 publications

(52 citation statements)

References 26 publications

(42 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Measuring psychosocial factors before surgery enabled us to test this hypothesis in our study. Contrary to our expectations, and consistent with a recent observational study on VATS patients, 6 none of the pre-operative psychosocial variables were significantly associated with the presence of chronic pain. Our negative results may be due to the small sample size in our study and the large number of associations tested.…”

Section: Discussionsupporting

confidence: 77%

See 1 more Smart Citation

A Prospective Study of Chronic Pain after Thoracic Surgery

et al. 2017

View full text Add to dashboard Cite

Background The goal of this study was to detect the predictors of chronic pain at 6 months after thoracic surgery from a comprehensive evaluation of demographic, psychosocial, and surgical factors. Methods Thoracic surgery patients were enrolled 1 week before surgery and followed up 6 months postsurgery in this prospective, observational study. Comprehensive psychosocial measurements were assessed before surgery. The presence and severity of pain were assessed at 3 and 6 months after surgery. One hundred seven patients were assessed during the first 3 days after surgery, and 99 (30 thoracotomy and 69 video-assisted thoracoscopic surgery, thoracoscopy) patients completed the 6-month follow-up. Patients with versus without chronic pain related to thoracic surgery at 6 months were compared. Results Both incidence (P = 0.37) and severity (P = 0.97) of surgery-related chronic pain at 6 months were similar after thoracotomy (33%; 95% CI, 17 to 53%; 3.3 ± 2.1) and thoracoscopy (25%; 95% CI, 15 to 36%; 3.3 ± 1.7). Both frequentist and Bayesian multivariate models revealed that the severity of acute pain (numerical rating scale, 0 to 10) is the measure associated with chronic pain related to thoracic surgery. Psychosocial factors and quantitative sensory testing were not predictive. Conclusions There was no difference in the incidence and severity of chronic pain at 6 months in patients undergoing thoracotomy versus thoracoscopy. Unlike other postsurgical pain conditions, none of the preoperative psychosocial measurements were associated with chronic pain after thoracic surgery.

show abstract

Section: Discussionsupporting

confidence: 77%

“…5 A few studies evaluated results for chronic pain after video-assisted thoracic surgery (VATS, thoracoscopy); 5,6 however, the data were not sufficient to summarize.…”

Section: Introductionmentioning

confidence: 99%

A Prospective Study of Chronic Pain after Thoracic Surgery

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Cognitive and psychological factors have been reported to have important roles in the severity of postoperative pain (9,20,21,24). High levels of pain catastrophizing are associated with heightened pain experience and appear to contribute to the development of chronic pain (24).…”

Section: Discussionmentioning

confidence: 99%

“…High levels of pain catastrophizing are associated with heightened pain experience and appear to contribute to the development of chronic pain (24). However, Wildgaard and colleagues (9) reported that although pain-related functional impairment after VATS was lower, no psychological factors could be used to predict persistent postoperative pain. In addition, Khan and workers (24) reviewed pain catastrophizing and its association with postoperative pain and quality of life.…”

Section: Discussionmentioning

confidence: 99%

Is early postoperative administration of pregabalin beneficial for patients with lung cancer?—randomized control trial

Miyazaki¹,

Sakai²,

Sato³

et al. 2016

J. Thorac. Dis.

View full text Add to dashboard Cite

Background: Post-thoracotomy pain is an obstacle for lung-cancer patients even after introduction of less invasive surgical procedures. The aim of this prospective study was to evaluate if early postoperative administration of pregabalin is beneficial for patients with non-small cell lung cancer (NSCLC). Methods:We conducted a randomized open control trial. Patients with NSCLC were allocated randomly to epidural and nonsteroidal anti-inflammatory drug (NSAID) use for analgesia (control group) or pregabalin use (pregabalin group). Primary endpoint was the frequency of additional administration of a NSAID. Secondary endpoints were intensity of ongoing pain, frequency of neuropathic pain, and pain catastrophizing. Results: Seventy-two patients were registered and allocated. Thirty-four cases in the control group and 33 in the pregabalin group were assessed. Age, sex, body mass index (BMI), type of surgical procedure, type of lymph-node dissection, operation time, bleeding, duration of chest-tube insertion, and postoperative hospital stay between the two groups was not significantly different. Frequency of additional NSAID use between the control group (2±4 suppositories) and pregabalin group (2±3 suppositories) was not significantly different (P=0.62). Numeric Rating Scale (NRS) for the intensity of ongoing pain, frequency of neuropathic pain, and Pain Catastrophizing Scale (PCS) between each group were not significantly different at any time until 3 months after surgery. Conclusions: Early postoperative administration of pregabalin is not beneficial for patients with NSCLC.

show abstract

“…Postoperative pain after thoracic surgery deserves greater attention. If not solely because of a desire to relieve discomfort in the period following surgery, then in an effort to minimize the risk of development of chronic pain in the months and years The few studies that have been published (4,12,13), supports the findings of Bayman et al but larger studies are warranted to reach a final conclusion. A more aggressive approach to pain management and multimodal analgesia is warranted and further studies are still needed.…”

mentioning

confidence: 79%