Nutritional Support on the Medical Wards—Thought for Food

Kushner, Jonathan P.; Lacy, Joseph A.

doi:10.1001/jamainternmed.2015.7062

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…Subjects with a risk of malnutrition that is not confirmed with GLIM and who receive MNT can have adverse outcomes. This finding is explained by the fact that the energy and protein adequacy of nutritional therapy was suboptimal, and continuous tube feeding and PN may potentially desynchronize a range of anabolic metabolic processes 9 . Therefore, if not strictly necessary, it is better to not prescribe MNTs because they are invasive and expensive 3 .…”

Section: Discussionmentioning

confidence: 99%

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Characteristics of patients receiving nutrition care and its associations with prognosis in a tertiary hospital

Pérez-Romero

Villanueva-Juárez

Serralde‐Zúñiga

et al. 2022

Rev. Assoc. Med. Bras.

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OBJECTIVE:The aim of this study was to describe the medical nutritional therapy (MNT) of adult non-critically ill hospitalization patients. METHODS: In a retrospective study, adults hospitalized for more than 48 h in non-intensive care unit medical and surgical areas that were classified as being at nutritional risk were included. Malnutrition was defined according to Global Leadership Initiative on Malnutrition (GLIM) criteria. RESULTS: A total of 255 patients, aged 54.13±18.4 years, who were at risk of malnutrition were included in this study. Of these, 50% were males. Notably, 52.5% received oral nutrition supplementation (ONS), 23.5% enteral nutrition (EN), 15% parenteral nutrition (PN), and 9% received enteral and parenteral nutrition (EPN). Patients with EPN presented the highest frequency of malnutrition (52%), and therefore they received more than 100% of energy and protein requirements. The median length of stay was 25 days. Among patients with nutritional risk receiving EPN, no deaths occurred. Patients, identified at nutritional risk, but without malnutrition according to GLIM, and receiving ONS had significantly lower mortality than patients receiving other MNT. CONCLUSIONS: Oral nutrition supplementation was the more frequent MNT prescribed. The frequency of malnutrition and percentage of prescribed energy and protein were higher in patients receiving PN and EPN compared with those receiving ONS.

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Section: Discussionmentioning

confidence: 99%

“…Patients with multiple comorbidities often have varying degrees of chronic malnutrition exacerbated by acute or chronic medical illness, which presents challenges to the nutritional and metabolic milieu. In addition, even negative outcomes of nutrition interventions have been reported 6 , 9 .…”

Section: Introductionmentioning

confidence: 99%

Characteristics of patients receiving nutrition care and its associations with prognosis in a tertiary hospital

Pérez-Romero

Villanueva-Juárez

Serralde‐Zúñiga

et al. 2022

Rev. Assoc. Med. Bras.

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“…Despite these considerations, there is currently no single study providing “unequivocal evidence that feeding protocols targeting full-replacement nutrition early in the course of critical illness result in clinical benefits” [ 4 ]. A number of factors have been pointed out to contribute to the controversy, including variation in the “timing, route, and composition of nutritional interventions” [ 5 ]. Another aspect seldom addressed is that nutritional support likely exerts its effect not only through the nutritional composition of nutrients (micro- and macronutrients) but also through the physiological response to food.…”

Section: Introductionmentioning

confidence: 99%

The role of bile acids in nutritional support

et al. 2018

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Nutritional support continues to receive much attention as a possible intervention to prevent loss of lean tissue mass, promote recovery and re-establish proper immune function in critical care patients. Yet there remains much controversy regarding the clinical efficacy of such interventions. In addition to the direct effect of nutrition in terms of micro- and macronutrient content, nutritional formulations may exert an effect via the physiological response to feeding. Here, we highlight the key role of postprandial reabsorbed bile acids in attenuating both the inflammatory response and autophagy. These observations suggest that not all patients would benefit from aggressive nutritional support.

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Nutritional Support on the Medical Wards—Thought for Food

Cited by 2 publications

References 9 publications

Characteristics of patients receiving nutrition care and its associations with prognosis in a tertiary hospital

Characteristics of patients receiving nutrition care and its associations with prognosis in a tertiary hospital

The role of bile acids in nutritional support

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