A traditional herbal medication, Maekmoondong-tang, for cough: A systematic review and meta-analysis

Shin, Sei One; Lee, Nara; Lee, Beom-Joon; Lee, Junhee; Lee, Hyangsook

doi:10.1016/j.jep.2015.12.005

Cited by 17 publications

(6 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most Chinese herbs present in SSY, including Panax ginseng [20], Folium perillae [21], Pueraria lobata [22], Poria cocos [23], Fructus aurantii [24], Platycodon grandi orum [25], pericarpium citri reticulatae [26], Glycyrrhiza uralensis sch [27], Costus root [28], Zingiber O cinale Radix [29] and Zizyphi fructus [30], have shown anti-in ammatory and/or anti-oxidative effects. Additionally, Peucedani radix, another component of SSY, exhibits a wide spectrum of pharmacological activities including anti-infective, antitussive, anti-asthmatic and expectorant effects, which help relieve symptoms and improve ALI prognosis [31].…”

Section: Discussionmentioning

confidence: 99%

Shen-su-yin, a Traditional Herbal Medicine, Attenuates Lipopolysaccharide-induced Acute Lung Injury in Rats Through Its Anti-inflammatory and Anti-oxidative Effects

Xiao

Zhang

et al. 2021

Preprint

View full text Add to dashboard Cite

Most components of Shen-su-yin (SSY), an herbal formula, have anti-inflammatory and antioxidant activities. The present study was designed to investigate potential effects and mechanisms of SSY on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in rats. 48 rats were randomly divided into 4 groups: control (Ctrl) group, LPS-induced ALI group, low- (SSY-LD) and high- (SSY-HD) dose SSY-treated ALI group. SSY was administered to SSY-treated rats immediately after LPS induction. After 24 hours, blood gas analysis and lactate determination were performed; and bronchoalveolar lavage fluid was collected for detecting protein concentration and levels of cytokines. Lung tissues were obtained for Western blot analysis, histopathological analysis, wet-to-dry weight ratio calculation and measurement of oxidative stress levels. SSY improved oxygenation index and mean arterial pressure, decreased levels of lactate and heart rate, alleviated lung histopathology indexes including lung injury score, wet-to-dry weight ratio and exudation of protein as well as inflammatory cells in ALI rats. Furthermore, SSY reduced levels of pro-inflammatory and oxidative mediums, while increasing levels of anti-inflammatory cytokine and anti-oxidative activity in lung tissues. SSY also suppressed NF-κB signalling pathway and further activated Keap1-Nrf2-ARE signalling pathway activated by LPS. Moreover, all the effects caused by SSY in the SSY-HD group were more encouraging than those in the SSY-LD group. The results indicate that the preventive use of SSY can alleviate ALI through the anti-inflammatory and antioxidant effects mediated by inhibition of NF-κB signalling pathway and activation of Keap1-Nrf2-ARE signalling pathway, and the effect of high dose is better.

show abstract

Section: Discussionmentioning

confidence: 99%

Shen-su-yin, a Traditional Herbal Medicine, Attenuates Lipopolysaccharide-induced Acute Lung Injury in Rats Through Its Anti-inflammatory and Anti-oxidative Effects

Xiao

Zhang

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…The herbal medicine interventions are usually complex and highly variable, and hence a detailed report on the quality and preparation of the herbal medicine that follows the relevant reporting guidelines is important. [38,39]…”

Section: Discussionmentioning

confidence: 99%

Herbal medicine (Hyeolbuchukeo-tang or Xuefu Zhuyu decoction) for treating primary dysmenorrhea

Leem

Kwon

et al. 2019

Medicine

View full text Add to dashboard Cite

show abstract

“…From another perspective, cough is one of the ways to enhance the transmission of the virus to the next victim, so inhibiting cough can help reduce the transmission between people (Morice et al, 2015). Cough is usually divided into three types: acute cough (lasting for less than three weeks), subacute cough (lasting for three to eight weeks), and chronic cough (persistent greater than eight weeks) (Kim et al, 2016). Acute cough is commonly associated with viral upper respiratory infection (O'Connell, 1998).…”

Section: Chinese Patent Medicine Shuang-huang-lianmentioning

confidence: 99%

Research Progress on Main Symptoms of Novel Coronavirus Pneumonia Improved by Traditional Chinese Medicine

Luo

Liu

et al. 2020

Front. Pharmacol.

View full text Add to dashboard Cite

Novel coronavirus (COVID-19) pneumonia has become a major threat to worldwide public health, having rapidly spread to more than 180 countries and infecting over 1.6 billion people. Fever, cough, and fatigue are the most common initial symptoms of COVID-19, while some patients experience diarrhea rather than fever in the early stage. Many herbal medicine and Chinese patent medicine can significantly improve these symptoms, cure the patients experiencing a mild 22form of the illness, reduce the rate of transition from mild to severe disease, and reduce mortality. Therefore, this paper summarizes the physiopathological mechanisms of fever, cough, fatigue and diarrhea, and introduces Chinese herbal medicines (Ephedrae Herba, Gypsum Fibrosum, Glycyrrhizae Radix et Rhizoma, Asteris Radix et Rhizoma, Ginseng Radix et Rhizoma, Codonopsis Radix, Atractylodis Rhizoma, etc.) and Chinese patent medicines (Shuang-huang-lian, Ma-xinggan-shi-tang, etc.) with their corresponding therapeutic effects. Emphasis was placed on their material basis, mechanism of action, and clinical research. Most of these medicines possess the pharmacological activities of anti-inflammatory, antioxidant, antiviral, and immunity-enhancement, and may be promising medicines for the treatment or adjuvant treatment of COVID-19 patients.

show abstract

A traditional herbal medication, Maekmoondong-tang, for cough: A systematic review and meta-analysis

Cited by 17 publications

References 36 publications

Shen-su-yin, a Traditional Herbal Medicine, Attenuates Lipopolysaccharide-induced Acute Lung Injury in Rats Through Its Anti-inflammatory and Anti-oxidative Effects

Shen-su-yin, a Traditional Herbal Medicine, Attenuates Lipopolysaccharide-induced Acute Lung Injury in Rats Through Its Anti-inflammatory and Anti-oxidative Effects

Herbal medicine (Hyeolbuchukeo-tang or Xuefu Zhuyu decoction) for treating primary dysmenorrhea

Research Progress on Main Symptoms of Novel Coronavirus Pneumonia Improved by Traditional Chinese Medicine

Contact Info

Product

Resources

About