Lower Gastrointestinal Bleeding in Children

Sahn, Benjamin; Bitton, Samuel

doi:10.1016/j.giec.2015.08.007

Cited by 44 publications

(48 citation statements)

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“…However, the false negative rate of CE is approximately 19%, especially for the diagnosis of vascular malformation, Meckel's diverticulum, and small intestinal malignant tumor [ 25 ]. However, systematic studies focusing on the clinical value of CE in pediatric OGIB patients are limited [ 2 , 5 , 13 , 26 – 29 ] and there are no related studies of MGCE. Therefore, the etiology of gastrointestinal bleeding in minors and the sensitivity, specificity, and predicting factors of MGCE require a study.…”

Section: Discussionmentioning

confidence: 99%

Magnetic-Guided Capsule Endoscopy in the Diagnosis of Gastrointestinal Diseases in Minors

Qian

Bai

et al. 2018

Gastroenterology Research and Practice

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Objective This study aimed at investigating the clinical value of magnetic-guided capsule endoscopy (MGCE) in the diagnosis of gastrointestinal diseases in minors. Methods Eighty-four minor patients hospitalized in the pediatric department at Ruijin Hospital between June 2015 and January 2018 were enrolled for this study. Following bowel preparation, all patients underwent MGCE. The feasibility, safety, diagnostic yield, and sensitivity of MGCE were analyzed. Patients were followed up for more than 2 weeks. Results The main indications for MGCE in minors were Crohn's disease, gastrointestinal bleeding, and abdominal pain. The main causes of gastric disease were gastric inflammatory hyperplasia, exudative gastritis, and polyps. The most common small bowel diseases in minors were Crohn's disease, Henoch-Schonlein purpura, and polyps. The diagnostic yield in the stomach and small intestine was 13.1% and 28.6%, respectively, and the sensitivity was 100% and 96.0%, respectively. No adverse events occurred. Conclusion MGCE is a safe, effective, and well-tolerated procedure with good sensitivity and has a potential clinic value for the diagnosis of gastrointestinal diseases in minors.

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Section: Discussionmentioning

confidence: 99%

Magnetic-Guided Capsule Endoscopy in the Diagnosis of Gastrointestinal Diseases in Minors

Qian

Bai

et al. 2018

Gastroenterology Research and Practice

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“…2 Pediatric Radiology Unit, Santobono-Pausilipon Children Hospital, Naples, Italy. 3 Department of Woman, Child and General and Specialistic Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy. 4 General and Emergency Radiology Unit, Antonio Cardarelli Hospital, Naples, Italy.…”

Section: Fundingmentioning

confidence: 99%

“…Colorectal polyps are reported in 6,1% of paediatric colonoscopies and in 12% of those performed for lower gastrointestinal bleeding. However, these lesions occur much more often than is clinically recognized because many of these polyps simply outgrow their blood supply, become ischaemic, and autoamputate with moderate painless haematochezia [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Faecal calprotectin and ultrasonography as non-invasive screening tools for detecting colorectal polyps in children with sporadic rectal bleeding: a prospective study

et al. 2020

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Background: Colorectal polyps are reported in 6,1% of paediatric colonoscopies and in 12% of those performed for lower gastrointestinal bleeding. Although colonoscopy is widely used in paediatric patients, it requires bowel preparation and general anaesthesia or deep sedation, and in rare cases, it can cause complications. Non-invasive screening techniques able to predict polyps in children with isolated and sporadic rectal bleeding may play a key role in the selection of patients needing colonoscopy. Methods: We enrolled all children undergoing colonoscopy for isolated and sporadic rectal bleeding to determine the diagnostic accuracy of faecal calprotectin, ultrasonography (US) and digital rectal examination as diagnostic methods for screening colorectal polyps. Results: A total of 26 of 59 enrolled patients (44.1%) had colonic polyps, one patient had multiple polyps, and 23% of children had polyps proximal to the splenic flexure. The diagnostic accuracy of faecal calprotectin for detecting colorectal polyps was 96.6%, with a sensitivity of 100%. False-positive faecal calprotectin was shown in 2 patients with non-steroidal anti-inflammatory drug-related lesions. The diagnostic accuracy of ultrasound was 77.9%. Polyps not seen with ultrasound tended to be relatively smaller (1.5 vs 2.3, p = 0.001) and located in the rectum. The combined use of FC, US and digital rectal examination obtained a specificity and PPV of 100%. Conclusions: FC combined with US and digital rectal examination is a good and promising non-invasive screening test for detecting colorectal polyps in children with isolated and sporadic rectal bleeding.

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“…Haematochezia describes bright red blood per rectum, which often arises from the distal colon or rectum . Lower gastrointestinal bleeding (LGIB) refers to any form of gastrointestinal bleeding originating distal to the ligament of Treitz, at the duodenojejunal junction . In childhood, LGIB is a more common complaint than upper gastrointestinal bleeding (UGIB) and is mostly self‐limiting .…”

Section: Haematocheziamentioning

confidence: 99%

“…A recent nationwide emergency department (ED) database analysis from 2006 to 2011 reported about 450 000 paediatric ED visits (ages birth to 19 years) for gastrointestinal bleeding, of which UGIB accounted for 20% and LGIB for 30% . In childhood, patient age is one of the most important factors in narrowing the aetiology of haematochezia at presentation . The most common causes are allergic colitis and anorectal fissures in infants, with colorectal polyps, infectious enterocolitis and anorectal fissures in older children …”

Section: Haematocheziamentioning

confidence: 99%