Antiretroviral therapy uptake among adult tuberculosis patients newly diagnosed with HIV in Nyanza Province, Kenya

Muttai, Hellen; Kf, Laserson; Akello, I; Nyabiage, Lennah; Gondi, Joel; Mutegi, Jane; Williamson, John D.; Ak, Nakashima; Ml, Ackers

doi:10.5588/pha.13.0072

Cited by 1 publication

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References 13 publications

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“…Subgroup analysis was done to find heterogeneity based on age, types of EPTB, study design, subregion of SSA, and countries having two or more studies and the time variation. For instance, by study population age group, inconsistency of the estimate was not removed, the EPTB among PLWHA did not vary by age group when we compared children <15 years, 23 , 28 , 39 adults ≥15 years 11 , 21 , 46 or ≥18 years 25 , 29 , 33 and all age groups in remaining 21 studies ( Table 3 ).…”

Section: Resultsmentioning

confidence: 99%

“… Notes: The number of studies and the sample size contributed by 12 countries from SSA that had included studies were as follows: ten studies with 2,837 people with HIV/AIDS were from Ethiopia, 18 – 27 four each were from Nigeria (2,042) 28 – 31 and South Africa (13,929), 32 – 35 and three were from Cameroon (2,246). 11 , 36 , 37 Two each were from Uganda (245) 38 , 39 and Zambia (471), 40 , 41 one each was from Tanzania (175), 42 Benin (521), 43 Burkina Faso (112), 44 Malawi (5,561), 45 Kenya (846), 46 and Gabon (205) 47 ( Table 1 ). …”

Section: Figurementioning

confidence: 99%

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Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in sub-Saharan Africa: a systemic review and meta-analysis

Mohammed

Assefa

Mengistie

2018

HIV

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BackgroundThe double burden of infectious diseases such as tuberculosis (TB) and HIV disproportionately affects Africa. Our objective was to summarize the prevalence of extrapulmonary TB (EPTB) among people living with HIV/AIDS (PLWHA) in sub-Saharan Africa (SSA).MethodsWe searched PubMed and Google Scholar for studies done on the prevalence of EPTB among PLWHA which published in English from 1990 to 2017. We also searched bibliographic indices and browsed through reference lists of articles and journals. We critically appraised the quality of articles and abstracted the data with Joanna Briggs Institute (JBI) checklists. We used Review Manager Software (version 5.3) and Compressive Meta-analysis Software (version 2.2) for analysis. Finally, we summarized the effect estimate by using random-effects model and explored potential sources of heterogeneity by subgroup and sensitivity analyses. We assessed publication bias by funnel plot and statistical test. Finally, we used PRISMA format for reporting.ResultsWe included, in this review, 31 studies that fulfilled our inclusion criteria, with a total population of 28,659. The prevalence estimate of EPTB among PLWHA ranged from 6.4% (95% CI: 3.8, 9.0) to 36.8% (95% CI: 28.6, 45); random-effects pooled prevalence of EPTB among PLWHA was found to be 20% (95% CI: 17, 22; heterogeneity: τ2=0; χ2=509.09, degrees of freedom [df]=30, P<0.00001; I2=94%). No evidence of publication bias was observed (P=0.44 for Egger’s regression analysis and P=0.11 for Begg’s rank correlation analysis).ConclusionWe can conclude from our analyses that the prevalence of EPTB among PLWHA was high. It is necessary to give emphasis for EPTB, especially when screening TB among PLWHA, widening the spectrum of screening to include all EPTB sites in the countries with high EPTB and/or HIV prevalence in the general population.

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Section: Resultsmentioning

confidence: 99%

Section: Figurementioning

confidence: 99%

Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in sub-Saharan Africa: a systemic review and meta-analysis

Mohammed

Assefa

Mengistie

2018

HIV

View full text Add to dashboard Cite

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Antiretroviral therapy uptake among adult tuberculosis patients newly diagnosed with HIV in Nyanza Province, Kenya

Abstract: Linking data increased documentation of HIV clinic enrollment and ART uptake. Continued efforts are required to improve the documentation of HIV service delivery, especially in TB clinics. Interventions to increase ART uptake are needed for younger patients and men.

Cited by 1 publication

References 13 publications

Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in sub-Saharan Africa: a systemic review and meta-analysis

Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in sub-Saharan Africa: a systemic review and meta-analysis

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