Polyethylene Glycol– or Sodium Picosulphate–Based Laxatives Before Colonoscopy in Children

Vejzovic, Vedrana; Wennick, Anne; Idvall, Ewa; Agardh, Daniel; Bramhagen, Ann‐Cathrine

doi:10.1097/mpg.0000000000000978

Cited by 18 publications

(25 citation statements)

References 24 publications

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“…There may be a risk if only one of these perspective is used when bowel cleansing before colonoscopy is planned. Bowel cleansing with PEG was experienced as the most difficult part of the procedure by both children and parents and this result is in accordance with previous quantitative studies [20,21,22,23]. These quantitative studies show difficulties with PEG intake based on a large volume and bad taste, however this study also shows that children were not psychologically prepared for this procedure.…”

Section: Discussionsupporting

confidence: 90%

“…The recommended intake of PEG is 25-35 ml/kg bodyweight per hour until clear intestinal fluid is obtained, either orally or by nasogastric tube [19]. Previous quantitative studies show that the intake of large volumes of bad-tasting laxative was the most difficult part of the procedure prior to colonoscopy from both the child's and parents' perspective [10,20,21,22,23]. A limitation of research in this area is that children's and parents' experiences of bowel cleansing have been largely neglected [10,11].…”

Section: Introductionmentioning

confidence: 99%

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Bowel Cleansing Prior to Pediatric Colonoscopy: The Children´s and Parent’s Perspective

Vejzovic¹

2017

ARC Journal of Nursing and Healthcare

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Bowel Cleansing Prior to Pediatric Colonoscopy: The Children´s and Parent’s Perspective

Vejzovic¹

2017

ARC Journal of Nursing and Healthcare

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“…Only a limited number of studies have evaluated the efficacy and safety of polyethylene glycol (PEG) 3350 powder in a 1-day bowel preparation regimen for pediatric colonoscopy [3][4][5][6][7][8][9][10][11][12]. Little is also known about the effectiveness and tolerability of sodium picosulphate/magnesium citrate before colonoscopy in children [9,[12][13][14].…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness, Tolerability, and Safety of Different 1-Day Bowel Preparation Regimens for Pediatric Colonoscopy

Szaflarska-Popławska

Tunowska

Sobieska-Poszwa

et al. 2019

Gastroenterology Research and Practice

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Background. Currently, there is no generally accepted universal protocol for bowel preparation before colonoscopy in children. Aim. The aim of the study was to compare three different 1-day bowel preparation methods for a pediatric elective colonoscopy in terms of their efficacy, safety, and patient-reported tolerability. Material and Methods. The study was randomized, prospective, and investigator-blinded. All children aged 10 to 18 years consecutively referred to the tertiary pediatric gastroenterology unit were enrolled. The participants were randomized to receive polyethylene glycol 3350 combined with bisacodyl (PEG-bisacodyl group), or polyethylene glycol 4000 with electrolytes (PEG-ELS group), or sodium picosulphate plus magnesium oxide plus citric acid (NaPico+MgCit group). Bowel preparation was assessed according to the Boston Bowel Preparation Scale (BBPS). For patient tolerability and acceptability, questionnaires were obtained. Results. One hundred twenty-three children were allocated to three age- and sex-matched groups. All of the patients completed colonoscopies with visualization of the cecum. There was no difference among the groups for the mean BBPS score. A total of 73 patients (59.3%) experienced minor adverse events. No serious adverse events occurred in any group. Nausea was the only symptom more frequent in the PEG-ELS group compared to the NaPico+MgCit group (p=0.04), and apathy was the only symptom more frequent in PEG-bisacodyl than in the NaPico+MgCit group (p=0.04). All of the patients were able to complete 75% or more of the study protocol, and 85.4% were able to complete the full regimen. The acceptability was the highest in the NaPico+MgCit group with respect to the patient’s grade for palatability, low volume of the solution, and willingness to repeat the same protocol. Conclusion. All bowel cleansing methods show similar efficacy. However, because of the higher tolerability and acceptability profile, the NaPico+MgCit-based regimen appears to be the most proper for colonoscopy preparation in children.

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“…This study was based on both quantitative and qualitative data as a third part of a large study ( Fig. 1) [7,11].…”

Section: Methodsmentioning

confidence: 99%

The experience of polyethylene glycol (PEG) bowel preparation in adolescents undergoing colonoscopy

et al. 2020

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Objective: The aim of this study was to describe the experience of polyethylene glycol (PEG) bowel preparation in adolescents undergoing colonoscopy.Results: 32 adolescents, 10-18 years of age self-reported a minimum of complications 1 week after colonoscopy when PEG was used for bowel preparation. 17 adolescents, 10-18 years were also interviewed about bowel preparation with PEG. Using qualitative content analysis, two categories were extracted from the data: "Being decisive makes it manageable" and "Be prepared for a horrible experience. " The adolescents reported PEG intake difficulty; the intake was, however, manageable if they received appropriate information.

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Polyethylene Glycol– or Sodium Picosulphate–Based Laxatives Before Colonoscopy in Children

Cited by 18 publications

References 24 publications

Bowel Cleansing Prior to Pediatric Colonoscopy: The Children´s and Parent’s Perspective

Bowel Cleansing Prior to Pediatric Colonoscopy: The Children´s and Parent’s Perspective

The Effectiveness, Tolerability, and Safety of Different 1-Day Bowel Preparation Regimens for Pediatric Colonoscopy

The experience of polyethylene glycol (PEG) bowel preparation in adolescents undergoing colonoscopy

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