The First Report from Bosnia and Herzegovina on Micro-tese Results in Azoospermic Patients

Göktolga, Ümit; Izetbegović, Sebija; Rama, Admir; Spahović, H.; Göktaş, C.

doi:10.5455/medarh.2015.69.196-199

Cited by 7 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These resulted in 41 clinical pregnancies (44.6%) and 26 live births (28.3%). Various authors have reported clinical pregnancy and live birth rates ranging from 26 to 57% for NOA [28–32]. All our patients had single ICSI cycles.…”

Section: Discussionmentioning

confidence: 83%

Microdissection testicular sperm extraction (micro‐TESE): Predictive value of preoperative hormonal levels and pathology in non‐obstructive azoospermia

Eken

Güleç

2017

The Kaohsiung J of Med Scie

View full text Add to dashboard Cite

The aim of this study was to evaluate the predictive value of preoperative hormonal levels and pathology, as well as the outcome of microsurgical testicular sperm extraction in patients with non-obstructive azoospermia (NOA), presenting to our clinic for treatment of infertility. The records of 145 men with NOA who underwent microdissection testicular sperm extraction (micro-TESE) between March 2013 and November 2016 were studied. The patient's age, testicular volume, hormonal profile for follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (TT), and testicular pathology were recorded. The sperm retrieval, the clinical pregnancy and live birth delivery rates were noted. Our testicular sperm retrieval rate was 65.5%. There was no statistical difference in age, testicular volume, or hormonal levels in the TESE-positive and negative groups. Hypospermatogenesis was found in testicular histopathology in 57 of 117 patients (48.7%) who underwent testicular biopsy. Sertoli Cell-Only (SCO) syndrome was seen in 20.5%, Germ Cell Maturation Arrest (MA) in 16.3%, and Atrophy-hyalinization in 14.5%. Seven men had Klinefelter's syndrome (KS), four of whom were TESE-positive. There were no adverse effects of the procedure except for infection at the incision site in one patient. Single intracytoplasmic sperm injection (ICSI) cycles were performed in 92 couples leading to 41 clinical pregnancies and 26 live birth deliveries. Micro-TESE is a safe procedure in experienced hands and provides infertile men with NOA an opportunity to father children. However unselected candidates with NOA should be counselled at the outset that only 17.9% will eventually become biological fathers.

show abstract

Section: Discussionmentioning

confidence: 83%

Microdissection testicular sperm extraction (micro‐TESE): Predictive value of preoperative hormonal levels and pathology in non‐obstructive azoospermia

Eken

Güleç

2017

The Kaohsiung J of Med Scie

View full text Add to dashboard Cite

show abstract

“…The standard for positive TESE procedure is 80-100% and for micro-TESE is about 50% whereas in recent studies the result is up to 60% (5, 6). Resent study from same group, prof.dr Ümit Göktolga et al had 52,7% positive sperm retrieval rate (SRR), and we have to consider that our examined group is smaller 21 patients, than 55 patients early examined (7). Relationship between etiological factors and determitants shows that most of patient had inguinal operations, orchidopexy or inginal canal repair (30%) and infections such parotitis and epididymoorchitis (20%) were in correlation with azoospermia in patients (8).…”

Section: Discussionmentioning

confidence: 93%

Evaluation of prognostic factors and determinants in surgical sperm retrieval procedures in azoospermic patients

Spahović¹,

Göktolga²,

Dzelaludin³

et al. 2017

European Urology Supplements

View full text Add to dashboard Cite

“…The standard for positive TESE procedure is 80-100% and for micro-TESE is about 50% whereas in recent studies the result is up to 60% ( 5 , 6 ). Resent study from same group, prof.dr Ümit Göktolga et al had 52,7% positive sperm retrieval rate (SRR), and we have to consider that our examined group is smaller 21 patients, than 55 patients early examined ( 7 ). Relationship between etiological factors and determitants shows that most of patient had inguinal operations, orchidopexy or inginal canal repair (30%) and infections such parotitis and epididymoorchitis (20%) were in correlation with azoospermia in patients ( 8 ).…”

Section: Discussionmentioning

confidence: 96%

Evaluation of Prognostic Factors and Determinants in Surgical Sperm Retrieval Procedures in Azoospermic Patients

Spahović

Göktolga²,

Junuzović

et al. 2017

Med Arch

Self Cite

View full text Add to dashboard Cite

Introduction:Main categorisation of azospermic is in two grups: nonobstructive azoospermia (NOA) and obstructive azoospermia (OA). We had evaluation of prognostic factors and determinants in sperm retrieval procedures in azoospermic patients.Methods:Retrospective evaluation observed 21 selected patients with NOA and OA azoospermia, after that complete history, physical examination with ultarsound volume of testis and hormonal profile. Hormonal profile included: follicle stimulating hormone (FSH), luteinizing hormone (LH), testosteron (T) and prolactin (P) serum levels. Also karyotype and Y-deletion analysis were done and analyzed.Results:9 OA patients (42,9%) were undergone for TESE operation and 12 NOA patients (57,1%) for Micro-TESE operation. All TESE procedures were positive (100%). Micro-TESE in 12 selected NOA patients, 5 patients (41,6%) were positive and 7 patients (58,4%) negative. Patients testicular size, serum FSH and testosterone level showed correlation in success of sperm retrieval procedures.Conclusion:TESE is elected procedure for obstructive azospermia (OA). Micro-TESE is appropriate sperm retrieval procedurec for patients with non-obstructive azoospermia (NOA) and correlate with high FSH and small volume of testis.

show abstract

The First Report from Bosnia and Herzegovina on Micro-tese Results in Azoospermic Patients

Cited by 7 publications

References 6 publications

Microdissection testicular sperm extraction (micro‐TESE): Predictive value of preoperative hormonal levels and pathology in non‐obstructive azoospermia

Microdissection testicular sperm extraction (micro‐TESE): Predictive value of preoperative hormonal levels and pathology in non‐obstructive azoospermia

Evaluation of prognostic factors and determinants in surgical sperm retrieval procedures in azoospermic patients

Evaluation of Prognostic Factors and Determinants in Surgical Sperm Retrieval Procedures in Azoospermic Patients

Contact Info

Product

Resources

About