Undiagnosed Lyme disease in adults with schizophrenia

Koola, Maju Mathew; Sullivan, Kelli; Earl, Amber; Feldman, Stephanie; Richardson, Christopher A.; Vyas, Gopal; Wehring, Heidi J.; Kelly, Deanna L.

doi:10.1016/j.schres.2015.06.029

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…Clinicians working in the endemic, high-risk areas should consider Lyme disease in the differential diagnosis of any atypical psychiatric presentation. Further research is warranted to investigate the differential diagnosis of Lyme disease and schizophrenia and examine the mechanisms and treatment of Lyme disease in mental illness” [32].…”

Section: Resultsmentioning

confidence: 99%

Proposed Lyme Disease Guidelines and Psychiatric Illnesses

Bransfield

Cook²,

Bransfield³

2019

Healthcare

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The Infectious Disease Society of America, American Academy of Neurology, and American Academy of Rheumatology jointly proposed Lyme disease guidelines. Four areas most relevant to psychiatry were reviewed—the disclaimer, laboratory testing, and adult and pediatric psychiatric sections. The disclaimer and the manner in which these guidelines are implemented are insufficient to remove the authors and sponsoring organizations from liability for harm caused by these guidelines. The guidelines and supporting citations place improper credibility upon surveillance case definition rather than clinical diagnosis criteria. The guidelines fail to address the clear causal association between Lyme disease and psychiatric illnesses, suicide, violence, developmental disabilities and substance abuse despite significant supporting evidence. If these guidelines are published without very major revisions, and if the sponsoring medical societies attempt to enforce these guidelines as a standard of care, it will directly contribute to increasing a national and global epidemic of psychiatric illnesses, suicide, violence, substance abuse and developmental disabilities and the associated economic and non-economic societal burdens. The guideline flaws could be improved with a more appropriate disclaimer, an evidence-based rather than an evidence-biased approach, more accurate diagnostic criteria, and recognition of the direct and serious causal association between Lyme disease and psychiatric illnesses.

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Section: Resultsmentioning

confidence: 99%

Proposed Lyme Disease Guidelines and Psychiatric Illnesses

Bransfield

Cook²,

Bransfield³

2019

Healthcare

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“…Gilbert syndrome is an inherited disorder of bilirubin metabolism, with intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular injury or hemolysis, recently linked to a higher risk of psychosis (Pommerening Dornelles, Gama Marques, & Ouakinin, 2019). Lyme disease is a tick-borne infection caused by the spirochete Borrelia burgdorferi , with a wide range of clinical manifestations, including central nervous system involvement (Koola et al, 2015). Hughes disease, also known as the antiphospholipid antibody syndrome (APS), is an acquired systemic disorder associated with circulating autoantibodies to phospholipids that can manifest as psychosis (Graf, 2017).…”

Section: Introductionmentioning

confidence: 99%

Olfactory reference plus Truman symptoms in one patient with Gilbert syndrome and antiphospholipid antibodies (Hughes disease) secondary to probable chronic Lyme neuroborreliosis

Melo

Marques

2022

Psychol. Med.

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Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease

Lantos

Rumbaugh

Bockenstedt

et al. 2020

Clinical Infectious Diseases

206

164

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This evidence-based clinical practice guideline for the prevention, diagnosis, and treatment of Lyme disease was developed by a multidisciplinary panel representing the Infectious Diseases Society of America (IDSA), the American Academy of Neurology (AAN), and the American College of Rheumatology (ACR). The scope of this guideline includes prevention of Lyme disease, and the diagnosis and treatment of Lyme disease presenting as erythema migrans, Lyme disease complicated by neurologic, cardiac, and rheumatologic manifestations, Eurasian manifestations of Lyme disease, and Lyme disease complicated by coinfection with other tick-borne pathogens. This guideline does not include comprehensive recommendations for babesiosis and tick-borne rickettsial infections, which are published in separate guidelines. The target audience for this guideline includes primary care physicians and specialists caring for this condition such as infectious diseases specialists, emergency physicians, internists, pediatricians, family physicians, neurologists, rheumatologists, cardiologists and dermatologists in North America.

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Undiagnosed Lyme disease in adults with schizophrenia

Cited by 3 publications

References 9 publications

Proposed Lyme Disease Guidelines and Psychiatric Illnesses

Proposed Lyme Disease Guidelines and Psychiatric Illnesses

Olfactory reference plus Truman symptoms in one patient with Gilbert syndrome and antiphospholipid antibodies (Hughes disease) secondary to probable chronic Lyme neuroborreliosis

Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease

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