262 Adding cranberry extract to flexible cystoscopy profilaxis decreases urinary infection rates

Ciudin, A.; Sanchez, J.; Wahab, Abdul; Mando, S.; Alcaraz, A.

doi:10.1016/s1569-9056(15)60260-3

Cited by 2 publications

(1 citation statement)

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“…Of course, other considerations to decrease the risk of infection associated with catheterization are already being explored in the form of protein, silver and nitrazine coating of catheters, surface micropatterns on catheters and variable preprocedural meatal cleaning [21][22][23][24][25][26]. In addition, alternative UTI prophylaxis with cranberry juice, cranberry extract, Nacetylcysteine and lactobacilli is also an emerging field of research to consider in this ongoing debate [15,16,[27][28][29][30][31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Antibiotic prophylaxis for urodynamic testing in women: a systematic review

et al. 2020

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Introduction and hypothesis Urinary tract infection is the most common complication after urodynamic studies (UDS). Practice guidelines recommend against antibiotic prophylaxis based on an outdated review of the literature, which advised on the premise of "a lack of good quality studies" and based on an assumed low incidence not consistently supported by the literature. Objectives This systematic review aims to update the assessment of the efficacy of antibiotic prophylaxis compared with placebo or no treatment for prevention of urinary tract infection in females over the age of 18 years undergoing UDS. Methods MEDLINE, EMBASE, COCHRANE, DISSERTATIONS, conference proceedings and clinical trial registries were searched for relevant randomized controlled trials. Two authors independently screened and selected articles, assessed these for quality according to Cochrane guidelines and extracted their data. Results A total of 2633 records were screened, identifying three relevant randomized controlled trials. The one study that was critically appraised as being the least likely biased showed a statistically significant effect of antibiotic prophylaxis in reducing bacteriuria post UDS in female patients. The other two studies included in the review did not. None of the studies included were powered to show a significant change in the incidence of urinary tract infection following UDS in female patients receiving antibiotic prophylaxis versus no prophylaxis. Conclusions Similar to the 2012 Cochrane review on this subject, this systematic review demonstrated that antibiotic prophylaxis may decrease bacteriuria in women post UDS; however, further research is required to assess its effect on urinary tract infections in this context.

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Section: Discussionmentioning

confidence: 99%

Antibiotic prophylaxis for urodynamic testing in women: a systematic review

et al. 2020

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Antimicrobial agents for preventing urinary tract infections in adults undergoing cystoscopy

Zeng

Zhang

Bai

et al. 2019

Cochrane Database of Systematic Reviews

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BackgroundCystoscopy is commonly performed for diagnostic purposes to inspect the interior lining of the bladder. One disadvantage of cystoscopy is the risk of symptomatic urinary tract infection (UTI) due to pre-existing colonization or by introduction of bacteria at the time of the procedure. However, the incidence of symptomatic UTI following cystoscopy is low. Currently, there is no consensus on whether antimicrobial agents should be used to prevent symptomatic UTI for cystoscopy. ObjectivesTo assess the e ects of antimicrobial agents compared with placebo or no treatment for prevention of UTI in adults undergoing cystoscopy. Search methodsWe comprehensively searched electronic databases of the Cochrane Library, PubMed, Embase, LILACS, and CINAHL. We searched the WHO ICTRP and ClinicalTrials.gov for ongoing trials. We used no language or date restrictions in the electronic searches. We searched the reference lists of identified articles and contacted authors for related information. The last search of the electronic databases was 4 February 2019. Selection criteriaWe included randomized controlled trials (RCTs) or quasi-RCTs that compared any prophylactic antibiotic versus placebo, no treatment, or other non-antibiotic prophylaxis in adults undergoing cystoscopy. There was no restriction on the dose, frequency, formulation, duration, or mode of administration of the antibiotics. Data collection and analysisWe used standard methodological procedures expected by Cochrane. Our primary outcomes were systemic UTI, symptomatic UTI (composite of systemic and/or localized UTI), and serious adverse events. Secondary outcomes were minor adverse events, localized UTI, asymptomatic bacteriuria, and bacterial resistance. We assessed the quality of evidence using GRADE. Main resultsWe included 20 RCTs and two quasi-RCTs with 7711 participants, all of which compared antibiotic prophylaxis with placebo or no treatment control. We found no studies comparing antibiotic prophylaxis with non-antibiotic prophylaxis. Primary outcomesAntimicrobial agents for preventing urinary tract infections in adults undergoing cystoscopy (Review)

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262 Adding cranberry extract to flexible cystoscopy profilaxis decreases urinary infection rates

Cited by 2 publications

References 0 publications

Antibiotic prophylaxis for urodynamic testing in women: a systematic review

Antibiotic prophylaxis for urodynamic testing in women: a systematic review

Antimicrobial agents for preventing urinary tract infections in adults undergoing cystoscopy

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