26. Comparison of Caudal Epidural Anesthesia With Lidocaine-Distilled Water and Lidocaine-MgSO4 Mixture in Sheep

Bigham, A. S.; Sarvestani, Shafiei Z.; Shadkhast, Mohammad; Sharifi, Shahriar; Mahdavi, Mohamad-Hosein

doi:10.1136/rapm-00115550-200809001-00139

Cited by 1 publication

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lejuste (1985) described an inadvertent intrathecal injection of 1000 mg magnesium sulfate that produced a transient motor block followed by a complete resolution within 90 min and no neurologic deficit at long-term follow-up. The findings of the present study disagree with Bigham and Shafiei (2008) and Bigham et al (2009) who observed recumbency after epidural administration of lidocaine-distilled water and lidocaine-MgSO 4 (100 mg/ Kg).…”

Section: Discussioncontrasting

confidence: 99%

“…Heart rates, respiratory rates, rumen motility and rectal body temperatures, were not significantly different in comparison with base line values in all treatments throughout the time of the study. Similar results were obtained by Bigham and Shafiei (2008); Bigham et al (2009) and DeRossi et al (2012) who did not observe any cardiovascular side effects after spinal injection of MgSO 4 with different combination of analgesia or anesthesia in animals. These findings encourage the epidural use of MgSO 4 in goats.…”

Section: Discussionsupporting

confidence: 88%

“…Prolonged onset of analgesia time was observed after epidural injection of lidocaine-MgSO 4 mixture in comparison to lidocaine alone. Similar result was obtained by Bigham and Shafiei (2008) and Bigham et al (2009) who suggested that lowering the pH to 5.7 by adding MgSO 4 to lidocaine, could alter levels of ionized and nonionized forms of lidocaine and had a decreased non ionized form (cell membrane permeable form) so, the beginning of analgesia was prolonged.…”

Section: Discussionsupporting

confidence: 82%

“…As well as, in this study, the longest duration of epidural analgesia was achieved following administration of a lidocain-MgSO 4 combination in treatment IV (99.80 ± 2.35 min). This result is supported by Bigham and Shafiei (2008); Bigham et al (2009) and Dehghani and Bigham (2009). On the other hand, epidural injection of magnesium sulfate alone induced a short duration of analgesia with more delayed onset of sensory blockade in sheep (DeRossi et al, 2012).…”

Section: Discussionmentioning

confidence: 86%

“…Epidural administration of agents with greater duration of action is proper for procedures requiring long duration of analgesia. These agents include a fentanyl -magnesium combination in rats; lidocain-MgSo4 in sheep and goat and magnesium sulphate added to ketamine in sheep (Karasawa et al, 1998;Bigham and Shafiei, 2008;Bigham et al, 2009 andDeRossi et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

The Effect of Magnesium Sulphate on Lidocaine Epidural Analgesia in Goats

El-Daharawy

Helal

2012

Assiut Veterinary Medical Journal

View full text Add to dashboard Cite

Five adult baladi goats were used to evaluate the effect of different doses of magnesium sulphate (MgSo 4 ) that were injected epidurally in combination with lidocaine Hcl 2% on the duration and area of analgesia as well as side effects. Animals were treated as follow: treatment I was injected with lidocaine Hcl 2% (1 ml/7 kg). Treatments II, III and IV were injected with lidocaine Hcl 2% (1 ml/7 kg) in combination with 25, 50 and 100 mg MgSo 4 10%, respectively. Results revealed that onset of analgesia was delayed in treatments II, III and IV (3, 3.5 and 3.5 minute, respectively). Treatment IV produced the longest duration of analgesia (99.80 ± 2.35 min). There was a significant increase in the animal recumbency in treatment I as compared to other treatments. The extent of analgesic area was almost the same in all treatments that extended from perineum to T13. Ataxic effect recorded in different patterns in treated animals. Treatment I had the longest duration of recumbency followed by mild ataxia in treatment II. In other treatments, ataxia was not developed. In conclusion, the combination of 2% lidocaine with 100 mg MgSo 4 10% injected epidurally in goats resulted in prolonged duration of analgesia extending from the perineum to the flank region without ataxia, cardiovascular or respiratory side effects.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 88%