Association between retinal vein occlusion, axial length and vitreous chamber depth measured by optical low coherence reflectometry

Abstract

BackgroundResults of ocular biometric measurements in retinal vein occlusion (RVO) eyes are still inconclusive and controversial. The aim of this study was to evaluate the association between ocular axial length (AL), vitreous chamber depth (VCD) and both central (CRVO) and branch retinal vein occlusions (BRVO) using optical low coherence reflectometry (OLCR).MethodsBoth eyes of 37 patients with unilateral CRVO (mean age: 66 ± 14 years, male:female - 21:16) and 46 patients with unilateral BRVO (mean age: 63 ± 12 years, male:female - 24:22) were enrolled in this study. The control group consisted of randomly selected single eyes of 67 age and gender matched volunteers without the presence or history of RVO (mean age: 64 ± 14 years, male:female - 34:33). Optical biometry was performed by OLCR biometer (LenStar LS 900). Average keratometry readings, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), AL and VCD of eyes with RVO were compared with those of fellow eyes using paired t-tests and with those of control eyes using independent t-tests.ResultsMean CCT, ACD and LT, average keratometry readings of affected RVO eyes, unaffected fellow eyes and control eyes was not statistically different in either groups. In eyes with CRVO mean AL and VCD of affected eyes were significantly shorter than those of control eyes (p < 0.001, p < 0.05), mean difference in AL and VCD between the affected and control eyes was 0.56 ± 0.15 mm and 0.45 ± 0.19 mm, respectively. In eyes with BRVO, mean AL of the affected eyes was significantly shorter with a mean difference of 0.57 ± 0.15 mm (p < 0.001) and the VCD was significantly shorter with a mean difference of 0.61 ± 0.15 mm (p < 0.001) comparing with the control eyes.ConclusionShorter AL and VCD might be a potential anatomical predisposing factor for development either of CRVO or BRVO.

Optic Nerve Head in Central Retinal Vein Occlusion by Spectral-Domain OCT

“…We found a correlation between optic disc dimension and axial length, in agreement with results of Miglior et al (16). Consistent with Bandello et al (17), we found no significant difference in axial length compared with controls; other studies reported a shorter axial length in eyes with CRVO (18)(19)(20).…”

The effect of peripheral defocus on axial growth and modulation of refractive error in hyperopes

“…Having identified a mechanism to modulate axial growth holds promise for hyperopes, and provides a platform for an extension to this work. The ability to accelerate axial growth in hyperopes may help to decrease the risk of ocular comorbidities associated with small globes 6 , 7 , 8 , 9 as well as reduce the burden of refractive error in these children. 1 , 2 , 3 , 4 , 5 Furthermore, multifocal contact lenses in children with hyperopia appear to be well tolerated both from a handling and wearing perspective as well as providing good visual performance.…”

“…Unlike myopia, and despite the known visual consequences 1 , 2 , 3 , 4 , 5 and pathological implications of hyperopia, 6 , 7 , 8 , 9 there has been inertia to address the modulation of refractive error in hyperopic individuals. Hyperopia occurs as a consequence of insufficient ocular growth and a failure to emmetropise in childhood, with the majority of hyperopic refractive errors resulting from an eye that is too short for its refractive power.…”

Subkonjonktival Kanaması olan Hastalarda Refraktif Durum ve Aksiyel Uzunluğun Önemi

“…In our study, axial length, low anterior chamber depth, and hypermetropic refraction error were found in patients with hypertension. The short axial length causes the scleral canal to be smaller and the passing vessel structures pass through a narrower area (17). The results show that there is an increased risk of retinal vein occlusion in eyes with narrow anterior chamber (18)(19), short axial length (20)(21) and hyperopia (22-23) in various studies.…”