Abstract:Central odontogenic fibroma (COF) is an extremely rare benign tumor that accounts for 0.1% of all odontogenic tumors. It is a lesion associated with the crown of an unerupted tooth resembling dentigerous cyst. In this report, a 10-year-old male patient is presented, who was diagnosed with central odontogenic fibroma of simple type from clinical, radiological, and histopathological findings.
“…It may have dysplastic dentin, osteoid, or cementum-like calcifications. 3 5 6 14 15 16 18 19 Our case resembled the simple type.…”
Section: Discussionmentioning
confidence: 56%
“…COF is usually asymptomatic, involving slow expansion of the cortical bones. 6 14 20 21 Our case occurred in the mandible of a four-year-old boy and manifested as an asymptomatic firm swelling.…”
Section: Discussionmentioning
confidence: 86%
“…Recurrence is not common. 6 14 Since the tumor in our case showed aggressive behavior, resection of the lesion and installation of a bone graft were performed.…”
Section: Discussionmentioning
confidence: 95%
“…It involves the anterior part of the maxilla, whereas mandibular lesions affect the premolar and molar areas. 6 14 15 16 17…”
Section: Discussionmentioning
confidence: 99%
“…Aggressive types can cause root resorption or displace teeth. 1 2 3 9 14 On CT and CBCT scans, COF usually presents as an expansile homogenous mass that can erode and perforate the adjacent cortical boundaries. Thin and straight septae can also be noted in some lesions.…”
Central odontogenic fibroma (COF) is a rare benign tumor that accounts for 0.1% of all odontogenic tumors. A case of COF (simple type) of the mandible in a four-year-old boy is described in this report. The patient showed asymptomatic swelling in the right inferior border of the lower jaw for one week. A panoramic radiograph showed a poorly-defined destructive unilocular radiolucent area. Cone-beam computed tomography showed expansion and perforation of the adjacent cortical bone plates. A periosteal reaction with the Codman triangle pattern was clearly visible in the buccal cortex. Since the tumor had destroyed a considerable amount of bone, surgical resection was performed. No recurrence was noted.
“…It may have dysplastic dentin, osteoid, or cementum-like calcifications. 3 5 6 14 15 16 18 19 Our case resembled the simple type.…”
Section: Discussionmentioning
confidence: 56%
“…COF is usually asymptomatic, involving slow expansion of the cortical bones. 6 14 20 21 Our case occurred in the mandible of a four-year-old boy and manifested as an asymptomatic firm swelling.…”
Section: Discussionmentioning
confidence: 86%
“…Recurrence is not common. 6 14 Since the tumor in our case showed aggressive behavior, resection of the lesion and installation of a bone graft were performed.…”
Section: Discussionmentioning
confidence: 95%
“…It involves the anterior part of the maxilla, whereas mandibular lesions affect the premolar and molar areas. 6 14 15 16 17…”
Section: Discussionmentioning
confidence: 99%
“…Aggressive types can cause root resorption or displace teeth. 1 2 3 9 14 On CT and CBCT scans, COF usually presents as an expansile homogenous mass that can erode and perforate the adjacent cortical boundaries. Thin and straight septae can also be noted in some lesions.…”
Central odontogenic fibroma (COF) is a rare benign tumor that accounts for 0.1% of all odontogenic tumors. A case of COF (simple type) of the mandible in a four-year-old boy is described in this report. The patient showed asymptomatic swelling in the right inferior border of the lower jaw for one week. A panoramic radiograph showed a poorly-defined destructive unilocular radiolucent area. Cone-beam computed tomography showed expansion and perforation of the adjacent cortical bone plates. A periosteal reaction with the Codman triangle pattern was clearly visible in the buccal cortex. Since the tumor had destroyed a considerable amount of bone, surgical resection was performed. No recurrence was noted.
IntroductionCentral odontogenic fibroma (COF) is a rare, benign, slow-growing intraosseous odontogenic tumor, and accounts for 0.1% of all odontogenic tumors. It is often confused with other entities, such as keratocysts, ameloblastomas, and odontogenic myxomas. Complete enucleation followed by curettage is the treatment of choice for COF to ensure the lowest possible chance of recurrence.Case presentationWe report the case of a young Caucasian woman with COF that went undiagnosed for several years despite repeated radiologic examinations. Finally, a massive tumor was surgically removed and the wound was curetted. The specimen was histologically confirmed to be a COF. The patient remains under regular follow-up, and thus far there have been no clinical or radiologic signs of recurrence.DiscussionThis rare case of COF, which was documented over a period of 20 years, has helped us to describe the features of this tumor. It also confirms that adequate surgical treatment can lead to impressive bone regeneration in healthy individuals, as evident from the radiologic findings acquired before, during, and after enucleation of the COF in our patient. Our findings also confirm the view that COF has a favorable prognosis regardless of its final size.ConclusionEarly diagnosis is key to successful treatment of COF. The slow but steady increase in the size of a COF with no accompanying symptoms has not been reported previously. To our knowledge, this is the only documented case of a COF that has been under continuous radiologic observation for over 20 years.
Introduction: Central Odontogenic Fibroma (COF) is a rare benign odontogenic tumour of the jaws. Until its recent change in classification by the WHO in 2017, this entity has gone without an agreed upon definition for many years. For this reason, COF would remain largely unknown to practitioners. Corpus: The pedagogical objectives of this article are, through a systematic review of the literature using the PRISMA methodology, to list the epidemiological, aetiological, clinical, radiological, histological, therapeutic and prognostic characteristics of COF. All the data collected made it possible to establish a COF management summary for practitioners in order to optimize it. Conclusion: Based on the 135 cases listed, it appears that surgical enucleation is the treatment of choice for COF. The recurrence rate is low and malignant transformation has never been reported. However, regular clinical and radiological follow-up of patients over several years seems to be a justified precaution.
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