Clinical nutrition therapy in patients with short bowel syndrome in line with principles of personalized medicine

Sahin, Péter; Molnár, Andrea; Varga, Mária Zsófia; Bíró, I.; Kömíves, C; Fejér, C; Futó, Judit; Tomsits, Erika; Topa, L

doi:10.1556/oh.2014.29973

Cited by 2 publications

(2 citation statements)

References 22 publications

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“…In populations with an extreme body mass index (BMI) (BMI < 16kg/m 2 and BMI > 40 kg/m 2 ), IC was equally the first choice compared to predictive equations [ 25 ]. Several studies observed lower BMI values (16.6–21.3) in HPN patients [ 26 , 27 , 28 , 29 ]. Evaluating the accuracy of 18 predictive equations and IC for calculating REE in patients with underweight (BMI < 18.5), normal weight (18.5 < BMI < 30) and overweight (BMI > 30), all equations reached only an accuracy between 9–45% (BMI < 18.5), 12–52% (18.5 < BMI < 25), 39–58% (25 < BMI < 30) and 10–53% for BMI > 30 compared to IC [ 30 ].…”

Section: Nutritional Assessment Methodsmentioning

confidence: 99%

Energy Guidance Using Indirect Calorimetry for Intestinal Failure Patients with Home Parenteral Nutrition: The Right Bag Right at the Start

2023

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Intestinal failure is defined as the inability to absorb the minimum of macro and micronutrients, minerals and vitamins due to a reduction in gut function. In a subpopulation of patients with a dysfunctional gastrointestinal system, treatment with total or supplemental parenteral nutrition is required. The golden standard for the determination of energy expenditure is indirect calorimetry. This method enables an individualized nutritional treatment based on measurements instead of equations or body weight calculations. The possible use and advantages of this technology in a home PN setting need critical evaluation. For this narrative review, a bibliographic search is performed in PubMed and Web of Science using the following terms: ‘indirect calorimetry’, ‘home parenteral nutrition’, ‘intestinal failure’, ‘parenteral nutrition’, ‘resting energy expenditure’, ‘energy expenditure’ and ‘science implementation’. The use of IC is widely embedded in the hospital setting but more research is necessary to investigate the role of IC in a home setting and especially in IF patients. It is important that scientific output is generated in order to improve patients’ outcome and develop nutritional care paths.

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Section: Nutritional Assessment Methodsmentioning

confidence: 99%

Energy Guidance Using Indirect Calorimetry for Intestinal Failure Patients with Home Parenteral Nutrition: The Right Bag Right at the Start

2023

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“…Других нежелательных явлений за весь период применения ТГ не отмечено. Необходимо учитывать, что каждый больной ребенок индивидуален как по способности и срокам кишечной адаптации, так и по ответу на терапию и, соответственно, достижению и стабильности результата [31,32].…”

Section: описание клинических случаевunclassified

Successful experience in the use of teduglutide in children with short bowel syndrome

Тропина

Zmanovskaya

2022

RPJ

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The article presents an overview of current trends in the approach to the treatment of patients with short bowel syndrome (SBS), including the example of pediatric patients in the Tyumen region. SBC is an extremely rare nosological form in the practice of a clinician and, as a rule, patients with such a diagnosis require a multidisciplinary approach. The most common manifestations of the disease are symptoms of malabsorption: dumping syndrome, progressive weight loss, deficiency of macro- and micronutrients, other manifestations of dyspepsia and abdominal pain. Attention is drawn to the fact that the number and intensity of symptoms varies significantly among patients. The traditional tactic for treating such patients includes the need for lifelong parenteral nutrition or, as a necessary measure, intestinal transplantation. Rehabilitation measures in SBS children should take into account the requirements for correcting impaired absorption and restoring normal trophic status; relief of diarrhea, prevention and treatment of dysbiosis; control and correction of general digestive disorders. We found that the analogue of glucagon-like peptide 2 (GLP-2) - teduglutide - makes it possible to reduce the amount of parenteral nutrition, infusion time, and also achieve a complete transition to enteral autonomy. The method of treatment with Teduglutide is the most promising for patients of this category.

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Clinical nutrition therapy in patients with short bowel syndrome in line with principles of personalized medicine

Cited by 2 publications

References 22 publications

Energy Guidance Using Indirect Calorimetry for Intestinal Failure Patients with Home Parenteral Nutrition: The Right Bag Right at the Start

Energy Guidance Using Indirect Calorimetry for Intestinal Failure Patients with Home Parenteral Nutrition: The Right Bag Right at the Start

Successful experience in the use of teduglutide in children with short bowel syndrome

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