Green synthesized silver nanoparticles using Nelumbo nucifera root extract for efficient protein binding, antioxidant and cytotoxicity activities

Structural characterization, antioxidant and in vitro cytotoxic properties of seagrass, Cymodocea serrulata (R.Br.) Asch. & Magnus mediated silver nanoparticles

“…Therefore, our recorded IC 50 values were considered to be quite effective against HeLa cells. Sreekanth et al [48] have documented the minimum (56%) and maximum (83%) growth inhibition of AgNPs synthesized from Nelumbo nucifera on HeLa cells whereas our CS-AgNPs produced dose dependent cytotoxicity effect on HeLa cells with a maximum of 95% and minimum of 18% percentage of growth. Likewise, Ramalingam et al [49] have assessed the mortality of HeLa cells using methanolic extract of C. serrulata wherein they predicted that the potential is not only because of the cytotoxic effect, but also in terms of the potential for tumor reduction.…”

Capuli cherry-mediated green synthesis of silver nanoparticles under white solar and blue LED light

“…The broad band seen at 3281 cm −1 reveals the presence of an OH group, resulting from either alcoholic or polyphenolic stretching (Kumar, Smita, Cumbal, Debut, Camacho, et al, 2015), while the peaks around 2919 and 2850 cm −1 are attributed to an asymmetric stretching vibration of the C H bond in alkanes (Kumar et al, 2014a). The peaks around 1613 cm −1 may be attributed to C O/amide I groups (Kumar et al, 2014a;Kumar, Smita, Cumbal, Debut, Camacho, et al, 2015), and those at 1421 and 1238 cm −1 to C C/C OH groups (Sreekanth et al, 2014). The strong peak observed at 1017 cm −1 corresponds to secondary OH stretching of glucose or carbohydrate (Kumar et al, 2014a) in the CCE.…”

“…This clearly indicates that the BL-AgNPs possess a higher antioxidant activity, with an antioxidant ranking of BL-AgNPs » WLAgNPs > CCE at lower concentrations. This increased antioxidant activity is owing to the involvement of the CCE phytochemicals on the surface of the stabilized AgNPs (Kumar, Smita, Cumbal, & Debut, 2014d;Sreekanth et al, 2014), and also to the stabilization of the AgNPs activated by blue LED light irradiation. Also, the surface-to-volume ratio is higher for smaller nanoparticles, and this increased surface exposure may more easily scavenge the free radicals and create an enhancement of antioxidant efficacy (Singh, Amateis, Mahaney, Meehan, & Rzigalinski, 2008;Tamjid, Bagheri, Vossoughi, & Simchi, 2011).…”

“…Recently, green synthesis of AgNPs using plant materials has been gaining increased attention because of its ease of preparation, cost effectiveness, and lack of hazardous reagents (Akhtar, Panwar, & Yun, 2013). Plant materials, including leaves (Kumar, Smita, Cumbal, & Debut, 2014a), flowers (Philip, 2010), fruits (Kumar, Smita, Cumbal, Debut, Camacho, et al, 2015), seeds (Otari, Patil, Ghosh, & Pawar, 2014), oil (Kumar, Smita, Cumbal, & Debut, 2014b), bark (Sathishkumar et al, 2009), biomass (Kumar, Smita, Cumbal, & Debut, 2014c), and roots (Sreekanth, Ravikumar, & Eom, 2014) have already been reported in the literature. Since ancient times, both primary and secondary metabolites of plants (phytochemicals) have demonstrated their importance in human health applications, but the use of phytochemicals for the synthesis of metal nanoparticles still remains unexplored and is an area of great research potential.…”

Insights into the effect of N-acetyl-L-cysteine-capped CdTe quantum dots on the structure and activity of human serum albumin by spectroscopic techniques

“…The conformational changes of protein caused by ligand can be explored by UV-visible absorption spectroscopy, owing to the strong absorption peak at 208 nm reflecting the framework conformation of the protein [43]. Moreover, the shift of absorption peaks can reflect the changes of microenvironment of aromatic acid residues [44].…”