Usefulness of 64-detector Computed Tomography in the Diagnosis and Management of Patients With Congenital Heart Disease

Bret-Zurita, Montserrat; Cuesta, Emilio; Cartón, Antonio J.; Díez, Jesús; Aroca, Ángel; Oliver, José M.; Gutiérrez-Larraya, Federico

doi:10.1016/j.rec.2014.01.028

Cited by 6 publications

(6 citation statements)

References 33 publications

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“…Several studies have compared the performance of ECHO and 64-MSCT in coronary artery disease (CAD) patients as the target population, showing that left ventricular (LV) systolic function assessed by 64-MDST is very comparable to 2-month 2-dimensional (2D) echocardiography (TTE), and LV function is a powerful indicator of CAD [18]. Among CHD subjects, 64-dectector CT is also documented to detect unexpected cases [19]. However, few studies have meticulously compared 64-MDST and ECHO in terms of cardiac malformation, malformation in the connecting area between heart and large vascular, and large vascular malformation.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Echocardiography and 64-Multislice Spiral Computed Tomography for the Diagnosis of Pediatric Congenital Heart Disease

Peng

Zhang

2017

Med Sci Monit

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BackgroundThe goals of this study were: to compare echocardiogram and 64-multislice spiral computed tomography (64-MSCT) in diagnosing pediatric congenital heart disease; to determine the significance of ECHO for diagnosing congenital heart disease; and to identify the appropriate diagnosis for congenital heart disease through combined use of 64-MSCT and ECHO.Material/MethodsThirty patients underwent both ECHO and 64-MSCT diagnoses before their surgeries. Imaging from ECHO and 64-MSCT were analyzed by 4 specialists. The diagnostic accuracy and kappa value of ECHO and 64-MSCT were evaluated based on the operation results. The accuracy of the 2 methods was evaluated using the McNemar χ2 test.ResultsWe confirmed 138 malformations in 30 children by surgery. The diagnostic accuracy of ECHO and 64-MSCT was 98.40% and 96.20%, respectively, with a significant difference between the 2 results (χ2=6.404, P=0.011). We compared prognosis accuracy and uniformity on 3 types of congenital heart disease (cardiac malformation, heart-large vascular connecting malformation, and large vascular malformation): 56 cardiac malformations were confirmed by surgery, in which the diagnostic accuracy of ECHO and 64-MSCT was 99.50% and 94.80%, respectively. (χ2=8.578, P=0.034); 31 heart-large vascular connecting malformations were confirmed by surgery, in which the diagnostic accuracy of ECHO and 64-MSCT was 99.00% and 95.42% (χ2=6.779, P=0.009); and 51 vascular malformations were confirmed, in which the diagnostic accuracy of ECHO and 64-MSCT was 96.30% and 98.30% (χ2=1.806, P=0.179).ConclusionsECHO is more effective than 64-MSCT in preoperative diagnosis of congenital heart disease, especially for children.

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Section: Introductionmentioning

confidence: 99%

Comparison of Echocardiography and 64-Multislice Spiral Computed Tomography for the Diagnosis of Pediatric Congenital Heart Disease

Peng

Zhang

2017

Med Sci Monit

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“…El avance tecnológico en otras técnicas de imagen cardíaca, como la cardio-TC y la cardio-RM, han permitido aumentar la resolución espacial y la precisión diagnóstica con mínimo riesgo para el paciente, permitiendo una reducción de métodos invasivos como el cateterismo diagnóstico (4) . En un estudio de 222 pacientes con anomalías congénitas sometidos a cardio-TC (4) , con una edad media de 12,8 años, sólo precisó cateterismo complementario el 12,5%. Se detectaron hallazgos nuevos en el 77%, resultando en un cambio de conducta en el 35,6% (11,3% debido a cambio de diagnóstico).…”

Section: Discussionunclassified

“…Se registraron más diagnósticos no esperados en peticiones urgentes de enfermedad aórtica y menores de 1 año de edad (p < 0,01). La cardio-TC permite sustituir las técnicas invasivas para el diagnóstico anatómico, sobre todo en neonatos, donde la tasa de complicaciones pericateterismo, es del 10-20%, con una mortalidad de alrededor del 1% (4) .…”

Section: Discussionunclassified

Cardio-TC en la coartación aórtica compleja. Interrupción del arco aórtico con ventrículo derecho de doble salida

Urmeneta-Ulloa

Bret-Zurita

Arreo

et al. 2018

Rev Ecocar Pract (RETIC)

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La interrupción del arco aórtico se define por la falta de continuidad anatómica entre la aorta ascendente y la descendente, considerándose una forma extrema de coartación. Generalmente se encuentra asociada con otras anomalías cardíacas, como puede ser el ventrículo derecho de doble salida. El avance tecnológico en cardio-TC ha permitido en los últimos años una gran precisión diagnóstica con mínimo riesgo para el paciente. Se presenta el caso de un neonato de 4 días de vida con diagnóstico de coartación aórtica compleja estudiado mediante cardio-TC junto con una breve revisión bibliográfica del tema.

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“…In recent years, some new technology in fetal heart examination such as 3D and 4D ultrasound has become a hot research field and has gained a lot of new progress, especially the Spatiotemporal Image Correlation (STIC) which opens up a new window for fetal heart examination and provides the morphological basis for intrauterine therapy of CHD at the same time [ 27 – 30 ]. It was reported that the 64-detector computed tomography could provide a good diagnostic performance in congenital heart disease [ 31 ], which depends on the understanding of normal fetal cardiac anatomic structure; meanwhile, some new studies demonstrated that the identification and characterization of the cellular and molecular pathways involved in the differentiation and morphogenesis of specific cell types of the developing heart were crucial to understanding the process of cardiac development and the pathology associated with human congenital heart disease, and they found that the CHD5 (congenital heart disease 5 protein) was essential for CASZ1 (cardiac transcription factor CASTOR) function and that the CHD5-CASZ1 interaction was necessary for cardiac morphogenesis and numerous signaling pathways were critical for normal valve development which could be reexpressed in diseased valves [ 32 – 35 ]. The increased level of PTX3 is also an independent predictor of combined end point of left ventricle dysfunction or mortality at one year; combining the biomarker and the device could be of great utility since they monitor the severity of two pathophysiological different mechanisms: heart fibrosis and fluid overload [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

The Ultrasonic Microsurgical Anatomical Comparative Study of the CHD Fetuses and Their Clinical Significance

Xia

Wang

et al. 2015

BioMed Research International

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The aim of our study was to increase the detection rate of fetal cardiac malformations for congenital heart disease (CHD). The ultrasonic and microanatomical methods were combined to study the CHD cases firstly, which could provide the microsurgical anatomical basis to the prenatal ultrasonic diagnosis which was used in suspected CHD and help the sonographer to improve the quality of fetal cardiac diagnosis. We established the ultrasonic standard section of the 175 complex CHD cases and collected the fetal echocardiography image files. The induced/aborted fetuses were fixed by 4% paraformaldehyde and dissected by the ultrasonic microsurgical anatomy. This research could obtain the fetal cardiac anatomic cross-sectional images which was consistent with the ultrasonic standard section and could clearly show the internal structure of the vascular malformation that optimized the ultrasound examination individually. This method could directly display the variation of the CHD fetal heart clearly and comprehensively help us to understand the complex fetal cardiac malformation from the internal structure of the vascular malformation which was consolidated by the anatomical basis of the fetal heart. This study could improve the integrity and accuracy of the prenatal cardiac ultrasound examination tremendously.

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Usefulness of 64-detector Computed Tomography in the Diagnosis and Management of Patients With Congenital Heart Disease

Cited by 6 publications

References 33 publications

Comparison of Echocardiography and 64-Multislice Spiral Computed Tomography for the Diagnosis of Pediatric Congenital Heart Disease

Comparison of Echocardiography and 64-Multislice Spiral Computed Tomography for the Diagnosis of Pediatric Congenital Heart Disease

Cardio-TC en la coartación aórtica compleja. Interrupción del arco aórtico con ventrículo derecho de doble salida

The Ultrasonic Microsurgical Anatomical Comparative Study of the CHD Fetuses and Their Clinical Significance

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