Cyclic nucleotide gated channel 10 negatively regulates salt tolerance by mediating Na+ transport in Arabidopsis

Jin, Yakang; Jing, Wen; Qun, Zhang; Zhang, Wenhua

doi:10.1007/s10265-014-0679-2

Cited by 69 publications

(38 citation statements)

References 40 publications

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“…CNGCs are non-selective ion channels involved in mediation of Na + transport. The expression level of CNGC significantly decreased at 3.75‰ salinity compared with the control, which was in agreement with the findings reported in Arabidopsis that CNGC10 expression was inhibited when exposed to high salinity or low salinity for long time 36 . K + efflux antiporter was significantly down-regulated at 7.5‰ salinity, similar to the transcriptome analysis of grapevine (Vitis vinifera L.) under saline conditions 37 , implying the replacement of K + by Na + .…”

Section: Enrichment Of Go Categories For Degssupporting

confidence: 92%

Transcriptome analyses revealed molecular responses of Cynanchum auriculatum leaves to saline stress

Zhang

et al. 2020

Sci Rep

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Cynanchum auriculatum is a traditional herbal medicine in China and can grow in saline soils. However, little is known in relation to the underlying molecular mechanisms. In the present study, C. auriculatum seedlings were exposed to 3.75‰ and 7.5‰ salinity. Next, transcriptome profiles of leaves were compared. Transcriptome sequencing showed 35,593 and 58,046 differentially expressed genes (DEGs) in treatments with 3.75‰ and 7.5‰, compared with the control, respectively. Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of these DEGs enriched various defense-related biological pathways, including ROS scavenging, ion transportation, lipid metabolism and plant hormone signaling. further analyses suggested that C. auriculatum up-regulated Na + /H + exchanger and V-type proton Atpase to avoid accumulation of na + . The flavonoid and phenylpropanoids biosynthesis pathways were activated, which might increase antioxidant capacity in response to saline stress. The auxin and ethylene signaling pathways were upregulated in response to saline treatments, both of which are important plant hormones. Overall, these results raised new insights to further investigate molecular mechanisms underlying resistance of C. auriculatum to saline stress.www.nature.com/scientificreports www.nature.com/scientificreports/ and V-type proton ATPase, the flavonoid and phenylpropanoids biosynthesis pathways, the auxin and ethylene signaling pathways were upregulated to improve the antioxidant capacity of C. auriculatum in response to saline treatments. These changes might facilitate resistance of C. auriculatum to saline stress. Flavonoid and phenylpropanoids appear to play roles in resistance to salt tolerance in C. auriculatum, possibly due to its pharmacodynamics.

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Section: Enrichment Of Go Categories For Degssupporting

confidence: 92%

Transcriptome analyses revealed molecular responses of Cynanchum auriculatum leaves to saline stress

Zhang

et al. 2020

Sci Rep

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“…However, in rice root, the down-regulation of the rice ( Oryza sativa ) OsCNGC1 contributed to the superior tolerance of the cultivar FL478 to salt stress (Senadheera et al, 2009), as it could avert toxic Na + influx, in contrast with the sensitive cultivar, in which the gene was up-regulated by salinity stress. Also, Arabidopsis thaliana null mutants, Atcngc10 , were found to have enhanced growth under salt stress compared to wild-type plants (Jin et al, 2015). Furthermore, Atcngc3 T-DNA insertion mutants showed an increase in tolerance to high levels of NaCl and KCl (Gobert et al, 2006).…”

Section: Mechanisms Restricting Na+ Uptake Determine Tolerance To Salmentioning

confidence: 99%

The Role of Na+ and K+ Transporters in Salt Stress Adaptation in Glycophytes

et al. 2017

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Ionic stress is one of the most important components of salinity and is brought about by excess Na+ accumulation, especially in the aerial parts of plants. Since Na+ interferes with K+ homeostasis, and especially given its involvement in numerous metabolic processes, maintaining a balanced cytosolic Na+/K+ ratio has become a key salinity tolerance mechanism. Achieving this homeostatic balance requires the activity of Na+ and K+ transporters and/or channels. The mechanism of Na+ and K+ uptake and translocation in glycophytes and halophytes is essentially the same, but glycophytes are more susceptible to ionic stress than halophytes. The transport mechanisms involve Na+ and/or K+ transporters and channels as well as non-selective cation channels. Thus, the question arises of whether the difference in salt tolerance between glycophytes and halophytes could be the result of differences in the proteins or in the expression of genes coding the transporters. The aim of this review is to seek answers to this question by examining the role of major Na+ and K+ transporters and channels in Na+ and K+ uptake, translocation and intracellular homeostasis in glycophytes. It turns out that these transporters and channels are equally important for the adaptation of glycophytes as they are for halophytes, but differential gene expression, structural differences in the proteins (single nucleotide substitutions, impacting affinity) and post-translational modifications (phosphorylation) account for the differences in their activity and hence the differences in tolerance between the two groups. Furthermore, lack of the ability to maintain stable plasma membrane (PM) potentials following Na+-induced depolarization is also crucial for salt stress tolerance. This stable membrane potential is sustained by the activity of Na+/H+ antiporters such as SOS1 at the PM. Moreover, novel regulators of Na+ and K+ transport pathways including the Nax1 and Nax2 loci regulation of SOS1 expression and activity in the stele, and haem oxygenase involvement in stabilizing membrane potential by activating H+-ATPase activity, favorable for K+ uptake through HAK/AKT1, have been shown and are discussed.

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“…The transporters for Na + influx into the root are not fully known but include the PM cyclic nucleotide-gated channels CNGC3 (Gobert et al, 2006) and CNGC10 (Guo et al, 2008; Jin et al, 2015) in Arabidopsis . Na + ingress is opposed by the Annexin1 protein and the AGB1 heterotrimeric G protein subunit in Arabidopsis roots (Laohavisit et al, 2013; Yu and Assmann, 2015).…”

Section: Salinity Stress From Channel To Transcriptionmentioning

confidence: 99%

Calcium-Mediated Abiotic Stress Signaling in Roots

et al. 2016

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Roots are subjected to a range of abiotic stresses as they forage for water and nutrients. Cytosolic free calcium is a common second messenger in the signaling of abiotic stress. In addition, roots take up calcium both as a nutrient and to stimulate exocytosis in growth. For calcium to fulfill its multiple roles must require strict spatio-temporal regulation of its uptake and efflux across the plasma membrane, its buffering in the cytosol and its sequestration or release from internal stores. This prompts the question of how specificity of signaling output can be achieved against the background of calcium’s other uses. Threats to agriculture such as salinity, water availability and hypoxia are signaled through calcium. Nutrient deficiency is also emerging as a stress that is signaled through cytosolic free calcium, with progress in potassium, nitrate and boron deficiency signaling now being made. Heavy metals have the capacity to trigger or modulate root calcium signaling depending on their dose and their capacity to catalyze production of hydroxyl radicals. Mechanical stress and cold stress can both trigger an increase in root cytosolic free calcium, with the possibility of membrane deformation playing a part in initiating the calcium signal. This review addresses progress in identifying the calcium transporting proteins (particularly channels such as annexins and cyclic nucleotide-gated channels) that effect stress-induced calcium increases in roots and explores links to reactive oxygen species, lipid signaling, and the unfolded protein response.

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Cyclic nucleotide gated channel 10 negatively regulates salt tolerance by mediating Na+ transport in Arabidopsis

Cited by 69 publications

References 40 publications

Transcriptome analyses revealed molecular responses of Cynanchum auriculatum leaves to saline stress

Transcriptome analyses revealed molecular responses of Cynanchum auriculatum leaves to saline stress

The Role of Na+ and K+ Transporters in Salt Stress Adaptation in Glycophytes

Calcium-Mediated Abiotic Stress Signaling in Roots

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