Interest in using rectal microbicides among Australian gay men is associated with perceived HIV vulnerability and engaging in condomless sex with casual partners: results from a national survey: Table 1

Murphy, Dean; Lea, Toby; Wit, John de; Ellard, Jeanne; Kippax, Susan; Rosengarten, Marsha; Holt, Martin

doi:10.1136/sextrans-2014-051694

Cited by 7 publications

(2 citation statements)

References 13 publications

(12 reference statements)

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“…However, although the acceptability of daily oral PrEP has been established in multiple settings 20–23 , there are relatively fewer studies assessing acceptability of long-acting injectables 16 and rectal microbicides. 18,24–27 Ultimately, it is likely that different PrEP modalities will be suitable for different individuals, and that a suite of options may allow for maximum population level benefit.…”

Section: Introductionmentioning

confidence: 99%

Antiretroviral pre-exposure prophylaxis preferences among men who have sex with men in Vietnam: results from a nationwide cross-sectional survey

Oldenburg

Le²,

Huyen³

et al. 2016

Sex. Health

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Introduction The HIV/AIDS epidemic in Vietnam is concentrated in groups including men who have sex with men (MSM). Pre-exposure prophylaxis (PrEP) is a viable strategy for HIV prevention, but knowledge about and preferences for PrEP delivery among Vietnamese MSM are not well understood. Methods In 2015, an online survey was conducted via social networking websites for MSM and by peer recruitment. A description of daily oral, long-acting injectable, and rectal microbicide formulations of PrEP was provided to participants. Participants were asked about their prior awareness of and interest in PrEP, and ranked their most preferred PrEP modality. Multivariable logistic regression models were used to assess factors associated with having heard of PrEP, and with preference for each PrEP modality. Results Of 548 participants who answered demographic and PrEP-related questions, 26.8% had previously heard of PrEP, and most (65.7%) endorsed rectal microbicides as their most preferred PrEP delivery modality. Commonly-cited perceived barriers to uptake of PrEP included concern about side-effects, perception about being HIV positive, and family/friends finding out about sexual behavior. In multivariable models, older participants less often endorsed rectal microbicides (aOR 0.95 per year, 95% CI 0.91–0.99) and more often endorsed long-acting injectables (aOR 1.08 per year, 95% CI 1.03 to 1.14) as their preferred PrEP modality. Participants who were willing to pay more for PrEP less often endorsed rectal microbicides (aOR 0.81, 95% CI 0.72–0.92) and more often endorsed long-acting injectables (aOR 1.17, 95% CI 1.01–1.35) and daily oral pills (aOR 1.16, 95% CI 1.00–1.35) as their preferred form of PrEP. Conclusions A variety of PrEP modalities were acceptable to MSM in Vietnam, but low knowledge of PrEP may be a barrier to implementation.

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Section: Introductionmentioning

confidence: 99%

Antiretroviral pre-exposure prophylaxis preferences among men who have sex with men in Vietnam: results from a nationwide cross-sectional survey

Oldenburg

Le²,

Huyen³

et al. 2016

Sex. Health

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“…Contrasting articles on HIV prevention, from different parts of the globe, remind us of its complexity. Mugo et al present an interesting study of HIV testing in Kenyan pharmacies15 while Vriend et al 16 describe STI and HIV testing patterns in Dutch MSM, and others explore acceptability and preparedness for treatment as prevention in Scotland17 and microbicides in Australia 18. Noting considerable variation in this popualtion, Logie at al 19 report on correlates of STI history in women who have sex with women and emphasize the need to tailor provision of services to sexual practices and history.…”

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confidence: 99%

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Cassell¹

2015

Sex Transm Infect

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Patterns of a Rectal Microbicide Placebo Gel Use in a Preparatory Stage for a Phase I Trial Among Young Men Who Have Sex with Men

et al. 2017

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We examined young gay, bisexual, and other men who have sex with men's (YGBMSM) usage patterns of a pre-coital, applicator-administered rectal placebo gel. An ethnically diverse sample of 94 YGBMSM (aged 18-30 years) were asked to insert hydroxyethylcellulose placebo gel rectally before receptive anal intercourse (RAI) and report their gel use through an interactive voice response system (IVRS) across 12 weeks. We used trajectory analyses to characterize participants' use of the rectal gel over the 12 weeks, and examine whether these trajectories varied based on participants' sociodemographic characteristics, sexual behaviors, application and insertion behaviors, and experiences using the placebo gel. A cubic model was the best fit for these longitudinal data, with two distinct trajectories of gel use observed. The first trajectory ('High with Varying Gel Use per Week') represented YGBMSM (N = 38; 40.3%) who reported using the rectal gel on several occasions per week. The second trajectory ('Low and Consistent Gel Use per Week') represented participants (N = 56; 59.7%) who reported a consistent average use of one gel per week. Participants in the High with Varying Gel Use Trajectory reported trying out a greater number of positions when inserting the gel across the 12-weeks than peers in the Low and Consistent Gel Use Trajectory. YGBMSM reporting more RAI occasions during the trial were more likely be present in the High with Varying Gel Use Trajectory than peers in the Low and Consistent Gel Use Trajectory. Future research examining how to facilitate gel application and adherence among YGBMSM is merited.

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Interest in using rectal microbicides among Australian gay men is associated with perceived HIV vulnerability and engaging in condomless sex with casual partners: results from a national survey: Table 1

Cited by 7 publications

References 13 publications

Antiretroviral pre-exposure prophylaxis preferences among men who have sex with men in Vietnam: results from a nationwide cross-sectional survey

Antiretroviral pre-exposure prophylaxis preferences among men who have sex with men in Vietnam: results from a nationwide cross-sectional survey

Highlights from this issue

Patterns of a Rectal Microbicide Placebo Gel Use in a Preparatory Stage for a Phase I Trial Among Young Men Who Have Sex with Men

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