Lupus erythematosus tumidus: a clinical and histological study of 25 cases

Rodriguez-Caruncho, C.; Bielsa, Isabel; Fernández‐Figueras, María‐Teresa; Roca, J; Carrascosa, J.M.; Ferrándiz, Carlos

doi:10.1177/0961203314560204

Cited by 24 publications

(33 citation statements)

References 11 publications

(34 reference statements)

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“…Accordingly, there are no data on the performance of rather unusual entities such as lupus tumidus, which is also rarely associated with SLE. [14][15][16] Similarly, the list of neuropsychiatric symptoms was expanded, and some of the other definitions were slightly modified.…”

Section: Sle Classification-the Acr and The Slicc Criteriamentioning

confidence: 99%

Toward new criteria for systemic lupus erythematosus—a standpoint

Aringer

Dörner

Leuchten

et al. 2016

Lupus

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While clearly different in their aims and means, classification and diagnosis both try to accurately label the disease patients are suffering from. For systemic lupus erythematosus (SLE), this is complicated by the multi-organ nature of the disease and by our incomplete understanding of its pathophysiology. Hallmarks of SLE are the presence of antinuclear antibodies (ANA), and multiple immune-mediated organ symptoms that are largely independent. In an attempt to overcome limitations of the current sets of SLE classification criteria, a new fourphase approach is being developed, which is jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). This review attempts to delineate the performance of the current sets of criteria, the reasons for the decision for classification, and not diagnostic, criteria, and to provide a background of the current approach taken. Lupus (2016) 25, 805-811.

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Section: Sle Classification-the Acr and The Slicc Criteriamentioning

confidence: 99%

Toward new criteria for systemic lupus erythematosus—a standpoint

Aringer

Dörner

Leuchten

et al. 2016

Lupus

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“…One of the described patients did not smoke, the other one stopped 3 years earlier. In LETpatients, ANAs are negative, and our patients were not different; according to Kuhn et al, they are confirmed only in 10% of patients [4,11]. The literature includes contradictory reports regarding the connection between lupus erythematosus and neoplasms.…”

Section: Discussionmentioning

confidence: 46%

Lupus tumidus

Nowowiejska¹,

Baran²,

Krahel³

et al. 2019

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Introduction:Lupus tumidus is a rare type of chronic cutaneous lupus erythematosus characterized by recurring non-scarring, erythematous--oedematous skin lesions, located on sun-exposed areas. Objective: To present two cases of patients with lupus tumidus. Case reports: 1. A 54-year-old woman was admitted to the Department of Dermatology due to erythematous-oedematous lesions on dorsal parts of hands, face and thighs, self-resolving. Broad evaluation for connective tissue disorders revealed no relevant abnormalities. Finally, lupus tumidus was diagnosed and hydroxychloroquine was introduced. During the therapy a breast cancer was diagnosed. 2. A 45-year-old woman presented to the Department in order to treat erythematousoedematous lesions located on the face, shoulders and upper torso that appeared 3 months earlier. The histopathological examination revealed lupus tumidus. Conclusions: Lupus erythematosus tumidus diagnosis may pose diagnostic difficulties. Among the types of lupus erythematosus, it is distinguished by regression without scarring, significant ultraviolet hypersensitivity and rapid clinical improvement after antimalarial drugs.streszczeNIe Wprowadzenie: Postać obrzękowa jest rzadką odmianą przewlekłego skórnego tocznia rumieniowatego o nawrotowym charakterze, charakteryzującą się występowaniem niebliznowaciejących, rumieniowo--obrzękowych zmian w okolicach eksponowanych na promieniowanie słoneczne. Cel: Opis przypadków dwóch pacjentek z postacią obrzękową tocznia rumieniowatego (LET). Opis przypadków: 1. Kobieta 54-letnia została przyjęta do Kliniki Dermatologii z powodu nawracających od 3 lat zmian rumieniowo-obrzękowych w obrębie grzbietów rąk, twarzy i ud. Przeprowadzona kompleksowa diagnostyka w kierunku układowych chorób tkanki łącznej nie wykazała istotnych nieprawidłowości. Ostatecznie rozpoznano postać obrzękową tocznia rumieniowatego i włączono hydroksychlorochinę. W trakcie terapii zdiagnozowano u chorej raka piersi. 2. Kobieta 45-letnia została przyjęta do Kliniki w celu leczenia zmian rumieniowo--obrzękowych w obrębie twarzy, ramion oraz górnej części klatki piersiowej utrzymujących się od 3 miesięcy. W badaniu histopatologicznym obraz odpowiadał postaci obrzękowej tocznia rumieniowatego.

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“…For ACLE, a total of 234 courses of AM use reported in two studies yielded an overall response rate of 91% (95% CI 87–93), with no heterogeneity ( P = 0·88, I 2 = 0%). For ICLE, the overall response rate was 68% (95% CI 56–78) with significant heterogeneity ( P = 0·01, I 2 = 61%) based on 145 courses of AM use reported in nine studies . For chilblain lupus, the cutaneous response was assessed in three studies, yielding a total of 58 courses of AMs.…”

Section: Resultsmentioning

confidence: 99%