25399 A 1% colloidal oatmeal OTC cream is clinically effective for the management of mild to moderate atopic dermatitis in African-American children

Lisante, Toni Anne; Kizoulis, Menas; Zhang, Paul; Nuñez, Carla Evelyn Coimbra

doi:10.1016/j.jaad.2021.06.252

Cited by 2 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was found that daily application of colloidal oatmeal extracts-containing lotion showed significant clinical improvements in 50 subjects with severely dry skin in as little as three weeks of treatment [107]. The efficacy is also demonstrated by another over-the-counter 1% colloidal oatmeal cream for pediatrics suffering from mild-to-moderate AD [108,109]. During the three weeks of the study period, significant improvements were demonstrated in clinical (EASI, IGA, and pruritus score) and objective assessment (erythema, dryness, skin hydration).…”

Section: Colloidal Oatmealmentioning

confidence: 99%

“…During the three weeks of the study period, significant improvements were demonstrated in clinical (EASI, IGA, and pruritus score) and objective assessment (erythema, dryness, skin hydration). This efficacy is non-inferior to a controlled prescribed cream (EpiCeram ® , Primus Pharmaceuticals, US) [108,109]. Colloidal oatmeal is thought to induce the repair of barrier damage, regulate lipid complex in SC, and enhance pH-buffering capacity, which aids in protection against irritants and normalizing cutaneous pH to its acidic range [107].…”

Section: Colloidal Oatmealmentioning

confidence: 99%

“…This may be associated with its ability to form a protective, occlusive barrier that retards water loss from the epidermis. In addition, the phytochemicals in oatmeal, such as saponins, may contribute to maintaining skin pH by solubilizing dirt, oil, and sebaceous secretions [108,109]. As a result of the evident pharmacological benefits, dermatologists have increasingly recommended the use of colloidal oatmeal-containing moisturizers for the treatment and prevention of AD.…”

Section: Colloidal Oatmealmentioning

confidence: 99%

See 2 more Smart Citations

A Review of Moisturizing Additives for Atopic Dermatitis

et al. 2022

View full text Add to dashboard Cite

Atopic dermatitis, the most common form of eczema, is a chronic, relapsing inflammatory skin condition that occurs with dry skin, persistent itching, and scaly lesions. This debilitating condition significantly compromises the patient’s quality of life due to the intractable itching and other associated factors such as disfigurement, sleeping disturbances, and social stigmatization from the visible lesions. The treatment mainstay of atopic dermatitis involves applying topical glucocorticosteroids and calcineurin inhibitors, combined with regular use of moisturizers. However, conventional treatments possess a certain degree of adverse effects, which raised concerns among the patients resulting in non-adherence to treatment. Hence, the modern use of moisturizers to improve barrier repair and function is of great value. One of the approaches includes incorporating bioactive ingredients with clinically proven therapeutic benefits into dermocosmetics emollient. The current evidence suggests that these dermocosmetics emollients aid in the improvement of the skin barrier and alleviate inflammation, pruritus and xerosis. We carried out a critical and comprehensive narrative review of the literature. Studies and trials focusing on moisturizers that include phytochemicals, natural moisturizing factors, essential fatty acids, endocannabinoids, and antioxidants were identified by searching electronic databases (PubMed and MEDLINE). We introduce the current knowledge on the roles of moisturizers in alleviating symptoms of atopic dermatitis. We then further summarize the science and rationale of the active ingredients in dermocosmetics and medical device emollients for treating atopic dermatitis. Finally, we highlight the limitations of the current evidence and future perspectives of cosmeceutical research on atopic dermatitis.

show abstract

Section: Colloidal Oatmealmentioning

confidence: 99%

Section: Colloidal Oatmealmentioning

confidence: 99%

Section: Colloidal Oatmealmentioning

confidence: 99%

See 1 more Smart Citation

A Review of Moisturizing Additives for Atopic Dermatitis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Colloidal oatmeal has historically been used as a soothing agent that can alleviate various dermatoses through anti-inflammatory, antioxidant, and hydrating properties (Kurtz & Wallo, 2007). Colloidal oatmeal has been shown to significantly improve symptoms of AD including itch (Lisante et al, 2017). It is available over-the-counter in the form of creams, shampoos, and powders, which can be used in baths.…”

Section: Treatmentmentioning

confidence: 99%

A New Era in the Management of Atopic Dermatitis

Golpanian

González

Yosipovitch

2021

Journal of the Dermatology Nurses' Association

View full text Add to dashboard Cite

Atopic dermatitis is a notoriously itchy condition that has profound effects on patient quality of life. The pathophysiology of this disease involves immune dysregulation, genetics, and environmental triggers contributing to barrier dysfunction characteristic of this disease. With advances in knowledge of atopic dermatitis pathophysiology, novel drugs have changed the lives of many patients. Furthermore, as dermatologic diseases are often a large component of primary care, it is important for the nurse practitioner to be aware of updates in management. The purpose of this article is to provide an updated review on the treatment of atopic dermatitis including novel therapies.

show abstract

25399 A 1% colloidal oatmeal OTC cream is clinically effective for the management of mild to moderate atopic dermatitis in African-American children

Cited by 2 publications

References 0 publications

A Review of Moisturizing Additives for Atopic Dermatitis

A Review of Moisturizing Additives for Atopic Dermatitis

A New Era in the Management of Atopic Dermatitis

Contact Info

Product

Resources

About