Trajectories of Depressive Symptoms in Women Prior to and for 6 Months After Breast Cancer Surgery

Kyranou, Maria; Puntillo, Kathleen; Aouizerat, Bradley E.; Paul, Steven M.; Cooper, Bruce A.; West, Claudia; Dodd, Marylin; Miaskowski, Christine; Dunn, Laura B.; Elboim, Charles

doi:10.1111/jabr.12017

Cited by 7 publications

(7 citation statements)

References 99 publications

(227 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…First, because we lacked depression measures prior to study enrollment, the nature and timing of patients’ symptomatology remain unknown. This is important because research has identified distinct trajectories of depression leading up to and following negative health events that differentially impact mortality risk (Kyranou et al, 2014; Oksholm et al, 2015). For example, one study of heart attack victims showed that newly emerging depression, but not chronic depression, was associated with mortality (Galatzer-Levy & Bonanno, 2014).…”

Section: Discussionmentioning

confidence: 99%

The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

Prescott¹,

Hull²,

Dionne‐Odom³

et al. 2017

Health Psychology

View full text Add to dashboard Cite

Objective Randomized controlled trials (RCTs) of early palliative care interventions in advanced cancer have positively impacted patient survival, yet the mechanisms remain unknown. This secondary analysis of two RCTs assessed whether an early palliative care intervention moderates the relationship between depressive symptoms and survival. Methods The relationships among mood, survival, and early palliative care intervention were studied among 529 advanced cancer patients who participated in two RCTs. The first (N=322) compared intervention vs. usual care. The second (N=207) compared early vs. delayed intervention (12 weeks after enrollment). The interventions included an in-person consultation, weekly nurse coach-facilitated phone sessions, and monthly follow-up. Mood was measured using the Center for Epidemiologic Studies Depression Scale (CES-D). Cox proportional hazard analyses were used to examine the effects of baseline CES-D scores, the intervention, and their interaction on mortality risk while controlling for demographic variables, cancer site, and illness severity. Results The combined sample was 56% male (mean = 64.7 years). Higher baseline CES-D scores were significantly associated with greater mortality risk (HR = 1.042, 95% CI 1.017 to 1.067, p = .001). However, participants with higher CES-D scores who received the intervention had a lower mortality risk (HR = .963, CI 0.933–0.993, p = .018) even when controlling for demographics, cancer site, and illness-related variables. Conclusions This study is the first to demonstrate that patients with advanced cancer who also have depressive symptoms benefit the most from early palliative care. Future research should be devoted to exploring the mechanisms responsible for these relationships.

show abstract

Section: Discussionmentioning

confidence: 99%

The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

Prescott¹,

Hull²,

Dionne‐Odom³

et al. 2017

Health Psychology

View full text Add to dashboard Cite

show abstract

“…All together, it seems like cancer-specific HA is a distinct phenomenon but demonstrates some overlap with anxiety, especially GAD. Associations with PTSD symptoms [ 43 , 56 , 207 , 208 ]; distress [ 56 , 155 , 209 , 210 ], depression [ 39 , 53 , 63 , 68 , 106 , 155 , 209 , 211 – 213 ], and lower quality of life (QOL) are frequently reported [ 44 , 45 , 49 , 66 , 106 , 138 , 143 ]. These relationships are likely bi-directional; for example, FCR predicts future depressive symptoms [ 211 ] and previous history of depression is a predictor of FCR [ 41 ].…”

Section: Synthesized Findingsmentioning

confidence: 99%

Health anxiety and illness-related fears across diverse chronic illnesses: A systematic review on conceptualization, measurement, prevalence, course, and correlates

et al. 2020

View full text Add to dashboard Cite

Background Patients with chronic diseases commonly report fears of illness or symptoms recurring or worsening. These fears have been addressed from an illness-specific perspective (e.g., fear of cancer recurrence), a generic illness perspective (e.g., fear of progression), and a psychiatric perspective (DSM-5 illness anxiety disorder and somatic symptom disorder). The broader concept of health anxiety (HA) can also be applied to patients with a chronic disease. This review was conducted to investigate the conceptual, theoretical, measurementoverlap, and differences between these distinct perspectives. We also aimed to summarize prevalence, course, and correlates of these fears in different chronic illnesses.

show abstract

“…Publications have focused on the identification of subgroups of patients with pain trajectories in the first post-operative week [5] and up to 6 months after breast cancer surgery [6,7]. Several significant factors associated with pain after breast cancer surgery have been identified, including preoperative pain intensity, anxiety, opioid consumption, age [8][9][10][11] and psychological distress [12]. Although surgery is the main cause for pain development, patients undergo other interventions including chemotherapy or radiotherapy in a succession that depends on the clinical situation.…”

Section: Introductionmentioning

confidence: 99%

“…Several significant factors associated with pain after breast cancer surgery have been identified, including preoperative pain intensity, anxiety, opioid consumption, age [ 8 , 9 , 10 , 11 ] and psychological distress [ 12 ]. Although surgery is the main cause for pain development, patients undergo other interventions including chemotherapy or radiotherapy in a succession that depends on the clinical situation.…”

Section: Introductionmentioning

confidence: 99%

Predicting Pain Trajectories in the One Year Following Breast Cancer Diagnosis—An Observational Study

Voute

Morel

Joly

et al. 2020

JCM

View full text Add to dashboard Cite

The impact of psychosocial vulnerability on pain in the year following breast cancer diagnosis has been little studied. To identify a score of psychosocial vulnerability (cognitive, emotional, quality of life and precariousness parameters) as a predictor of a pain trajectory, we conducted an observational prospective study and included women with newly diagnosed breast cancer. One year follow-up with 3 visits (day of breast cancer diagnosis; 6 and 12 months) aimed to identify distinct pain-time trajectories. Baseline psychosocial vulnerability was characterized by z-score transformation, a higher score representing a more vulnerable patient. A total of 89 patients were included (59.3 ± 10.7 years). Two trajectories of pain were identified—“Transient Pain trajectory” (TP) (39/89 patients) and “Persistent Pain trajectory” (PP) (50/89). A significant difference of pain over time between trajectories (PP vs. TP at 6 months: 2.23 ± 0.23 vs. 0.27 ± 0.09, p < 0.001) was observed. Psychosocial vulnerability showed a large effect size (d, −0.82; 95% CI, −1.25 to −0.38; p < 0.001) and a higher score in “Persistent pain trajectory” (PP vs. TP: 0.12 ± 0.36 vs. −0.14 ± 0.26, p < 0.001). A predictive vulnerability marker of pain development is proposed and could be used at cancer diagnosis to orientate the care pathway of patients experiencing breast cancer.

show abstract

Trajectories of Depressive Symptoms in Women Prior to and for 6 Months After Breast Cancer Surgery

Cited by 7 publications

References 99 publications

The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

Health anxiety and illness-related fears across diverse chronic illnesses: A systematic review on conceptualization, measurement, prevalence, course, and correlates

Predicting Pain Trajectories in the One Year Following Breast Cancer Diagnosis—An Observational Study

Contact Info

Product

Resources

About