Dihydrochalcones and homoisoflavanes from the red resin of Dracaena cochinchinensis (Chinese dragon's blood)

Phytochemical analysis of Vietnamese propolis produced by the stingless bee Lisotrigona cacciae

“…Further, selected isolated compounds were used as standards and subjected to GC/MS analysis in order to obtain information for their mass spectral characteristics as TMS derivatives, and then to recognize them in the TIC chromatogram. The data obtained (Table 2) revealed that the fragmentation pathways of the flavonoids 1 – 4 are in accordance with those proposed by Su et al [39] and Chen et al [40], who studied Chinese dragon's blood and its constituents by means of IT-TOF HRMS n and UHPLC-QTOF-MS/MS, respectively. In the mass spectra of the homoisoflavans 2 and 3 , the molecular ion was the most prominent peak (base peak), followed by B-ring and AC-rings fragments due to C 3 –C 9 and C 9 –C 1’ bond cleavages, which have been regarded as diagnostic for this type of flavonoids [40,41].…”

“…The first group includes the flavonoids 1 – 4 and liquiritigenin, and the stilbene resveratrol, among which the flavanes are well known constituents of the stem and red resin of Dracaena cochinchinensis (Agavaceae) [23,27,29,30,39,46]. The red resinous material, known as Chinese dragon’s blood, is a popular folk medicine used for treatment of fractures, wounds, stomach ulcers, etc.…”

Rapid Evaluation of Chemical Consistency of Artificially Induced and Natural Resina Draconis Using Ultra-Performance Liquid Chromatography Quadrupole-Time-of-Flight Mass Spectrometry-Based Chemical Profiling

“…The characteristic fragments, primary cleavages, and MS/MS spectrum of compound 49 are elucidated in Figure 4 . Compared with reference and literature data [ 13 , 26 ], compound 49 was identified to be loureirin B. It is interesting to note that there were common fragment ions observed at most of the dihydrochalcone compounds at m / z 147.05, 134.04 and 120.02, which could due to the successive neutral loss of the B ring at the positions of II, III and IV bond.…”

Longxuetongluo Capsule Improves Erythrocyte Function against Lipid Peroxidation and Abnormal Hemorheological Parameters in High Fat Diet‐Induced ApoE−/− Mice

“…The mobile phase was composed of acetonitrile (A) and 0.1% aqueous formic acid (B) and delivered at a total flow rate of 1.0 mL/min following a gradient program: 0–35 min, 20%–31% A; 35–45 min, 31%–31% A; and 45–80 min, 31%–55% A; UV absorption over 190–400 nm was recorded by Diode Array Detector (DAD), and fixed wavelength of 280 nm was used for the detection of phenolic constituents. The injection volume was set at 10 μ L. Ten phenolic compounds in LTC were identified as 7,4′-dihydroxyflavone ( 1 , t R 16.91 min), loureirin D ( 2 , t R 22.56 min), 7,4′-dihydroxyhomoisoflavanone ( 3 , t R 28.39 min), loureirin C ( 4 , t R 32.93 min), 3,4′-dihydroxy-5-methoxystilbene ( 5 , t R 43.59 min), 5,7-dihydroxy-4′-methoxy-8-methylflavan ( 6 , t R 56.61 min), 4-hydroxy-2,4′-dimethoxydihydrochalcone ( 7 , t R 62.78 min), loureirin A ( 8 , t R 64.70 min), loureirin B ( 9 , t R 65.98 min), and pterostilbene ( 10 , t R 72.48 min) by comparison of their retention times and UV spectra with those of authentic compounds [ 22 , 23 ]. The structures of the identified compounds are shown in Figure 2 .…”