Variability in quality of life 13 years after traumatic brain injury in childhood

Fatigue, Participation and Quality of Life in Adolescents and Young Adults with Acquired Brain Injury in an Outpatient Rehabilitation Cohort

“…[1][2][3][4][5][6][7] Fatigue is one of the most common physical symptoms occurring after pediatric ABI, irrespective of the severity of TBI 8,9 or NTBI (brain tumors 10 ; stroke 11 ), and may persist long after injury. 12 Although fatigue is difficult to define due to complex interactions between biological, behavioral and psychosocial processes, it can be seen as a multidimensional symptom with physical, mental and emotional components. 13 Fatigue was found to be associated with poorer psychosocial, physical, and (school) participation in childhood stroke 14 and brain tumors, 10 as well as other childhood conditions (multiple sclerosis 15 ; cerebral palsy 16 ; leukemia 17,18 ; chronic pain 19 ) as well as the adult stroke population.…”

Impact of multi‐modal web‐based rehabilitation on occupational performance and upper limb outcomes: pilot randomized trial in children with acquired brain injuries

“…Use of Mitii in the clinical post‐acute rehabilitation setting with supervision from therapists may also overcome these difficulties. Concentration and fatigue are often reported as long‐term problems experienced by children with ABI, which may suggest that shorter (<30min) intervention sessions may be preferable. In addition, our sample size calculation was determined from a unilateral CP population, because there were no available data on the AMPS for children with ABI.…”

Ongoing daytime behavioural problems in university students following childhood mild traumatic brain injury

“…Damage to one, some or all of these regions is likely to result in high variability across individual cases. Aaro Jonsson et al (2014) show this variability in individuals 13 years following TBI, reporting that outcomes for those with mTBI can vary considerably between 'relatively good' to 'mild to moderate limitations' with respect to quality of life. Moreover, factors that can contribute towards the variability in outcome may not solely be because of neurological insult, with Ponsford (2013) noting that personal and social factors can also influence outcome, including age, sex, genetics, education level, employment, premorbid functioning, social support and culture.…”

“…When considering the long-term effects of mTBI, it is first important to note that the nature of mTBI produces diffuse damage and heterogeneity in neurological insult (Bigler et al, 2013;Albicini and McKinlay, 2015), resulting in a large variability in behavioural outcomes (Ponsford, 2013;Aaro Jonsson et al, 2014). Bigler et al (2013) noted that lesion burden in children with TBI is broad, with insults occurring in frontal and temporal regions, and volume differences in white and grey matter, hippocampus, amygdala, thalamus and basal ganglia.…”