Metabolic Surgery for the Treatment of Type 2 Diabetes in Pancreas After Kidney Transplant Candidates

Gullo-Neto, S.; Padoin, Alexandre Vontobel; Carvalho, J.E. Queiroz de; Wendling, R.; Traesel, Moacir Alexandre; Kroth, Leonardo Viliano; Miranda, Carolina; Balestro, A. Colombo; Siqueira, Rodrigo Morais de; Lisot, Bruno Chao; Lima, Sizenando Ernesto de; Mottin, Cláudio Corá; Saitovitch, David

doi:10.1016/j.transproceed.2014.05.005

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…Four series included 24 kidney transplant recipients, most of whom saw a substantial decrease in BMI without major complications [ 81 , 109–111 ]. One patient died 4 months after the procedure from septic shock after developing splenic abscesses [ 111 ]. Data on graft function were not or ill reported.…”

Section: Chapter 5 What Are the Benefits And Harms Of Bariatric Surgery Performed After Kidney Transplantation?mentioning

confidence: 99%

“…The authors reported an average loss of 12 BMI points, a reduction in medications, improved blood pressure control and reduced insulin requirements with improvement in graft function and proteinuria in four patients. All experienced a significant improvement in their quality of life and there were no complications or reported deaths [ 112 , 111 ].…”

Section: Chapter 5 What Are the Benefits And Harms Of Bariatric Surgery Performed After Kidney Transplantation?mentioning

confidence: 99%

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Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA

Oniscu

Abramowicz

Bolignano

et al. 2021

Nephrology Dialysis Transplantation

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The clinical practice guideline ‘Management of obesity in kidney transplant candidates and recipients’ was developed to guide decision making in caring for people with end-stage kidney disease living with obesity. The document considers the challenges in defining obesity, weighs interventions for treating obesity in kidney transplant candidates as well as recipients and reflects on the impact of obesity on the likelihood of waitlisting as well as its effect on transplant outcomes. It was designed to inform management decisions related to this topic and provide the backdrop for shared decision making. This guideline was developed by ERA's Descartes working group on Transplantation. The group was supplemented with selected methodologists to supervise the project and provide methodological expertise in guideline development throughout the process. The guideline targets any health care professional treating or caring for people with end-stage kidney disease being considered for kidney transplantation or having received a donor kidney. This includes nephrologists, transplant physicians, transplant surgeons, general practitioners, dialysis and transplant nurses. Development of this guideline followed an explicit process of evidence review. Treatment approaches and guideline recommendations are based on systematic reviews of relevant studies, and appraisal of the quality of the evidence and the strength of recommendations followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Limitations of the evidence are discussed, and areas of future research are presented.

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Section: Chapter 5 What Are the Benefits And Harms Of Bariatric Surgery Performed After Kidney Transplantation?mentioning

confidence: 99%

Section: Chapter 5 What Are the Benefits And Harms Of Bariatric Surgery Performed After Kidney Transplantation?mentioning

confidence: 99%

Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA

Oniscu

Abramowicz

Bolignano

et al. 2021

Nephrology Dialysis Transplantation

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“…Obesity may increase the surgical complexity and is significantly associated with longer operative time and risk of wound dehiscence compared to normal-weight patients[ 62 ]. In obese patients, the risk of parietal dehiscence is significantly increased for BMI > 26 kg/m 2 , while an increased risk of intraoperative blood loss and ureteral stenosis was observed for BMI > 32 kg/m 2 , and the risk of abdominal wall hematoma was increased beyond a BMI of 34 kg/m 2 [ 63 ]. Overall, obese patients have an incidence of wound infections and incisional hernia of 4%-40% due to the longer operative time; the concomitant use of corticosteroids, sirolimus, or everolimus; and the presence of vascular disease[ 26 , 46 , 56 ].…”

Section: Obesity and Kidney Transplantationmentioning

confidence: 99%

Obesity and bariatric surgery in kidney transplantation: A clinical review

Veroux

Mattone

Cavallo

et al. 2021

WJD

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Obesity is increasing worldwide, and this has major implications in the setting of kidney transplantation. Patients with obesity may have limited access to transplantation and increased posttransplant morbidity and mortality. Most transplant centers incorporate interventions aiming to target obesity in kidney transplant candidates, including dietary education and lifestyle modifications. For those failing nutritional restriction and medical therapy, the use of bariatric surgery may increase the transplant candidacy of patients with obesity and end-stage renal disease (ESRD) and may potentially improve the immediate and late outcomes. Bariatric surgery in ESRD patients is associated with weight loss ranging from 29.8% to 72.8% excess weight loss, with reported mortality and morbidity rates of 2% and 7%, respectively. The most commonly performed bariatric surgical procedures in patients with ESRD and in transplant patients are laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass. However, the correct timing of bariatric surgery and the ideal type of surgery have yet to be determined, although pretransplant LSG seems to be associated with an acceptable risk-benefit profile. We review the impact of obesity on kidney transplant candidates and recipients and in potential living kidney donors, exploring the potential impact of bariatric surgery in addressing obesity in these populations, thereby potentially improving posttransplant outcomes.

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Bariatric surgery to achieve transplant in end-stage organ disease patients: A systematic review and meta-analysis

Orandi

Purvis

Cannon

et al. 2020

The American Journal of Surgery

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Metabolic Surgery for the Treatment of Type 2 Diabetes in Pancreas After Kidney Transplant Candidates

Cited by 5 publications

References 18 publications

Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA

Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA

Obesity and bariatric surgery in kidney transplantation: A clinical review

Bariatric surgery to achieve transplant in end-stage organ disease patients: A systematic review and meta-analysis

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