Lifestyle Interventions for Cardiovascular Disease Risk Reduction: A Systematic Review of the Effects of Diet Composition, Food Provision, and Treatment Modality on Weight Loss
Abstract:The purpose of this systematic review was to evaluate, synthesize, and interpret findings from recent randomized controlled trials (RCTs) of dietary and lifestyle weight loss interventions examining the effects of 1) diet composition, 2) use of food provision, and 3) modality of treatment delivery on weight loss. Trials comparing different dietary approaches indicated that reducing carbohydrate intake promoted greater initial weight loss than other approaches but did not appear to significantly improve long-te… Show more
“…Moreover, treatment can be delivered over many modalities (in-person, phonebased, and internet). 68 Clinical trials testing the effects of comprehensive behavioral programs have found weight losses averaging $10.7 kg (11% of body weight) over 30 weeks. 66,69 Nonetheless, even with comprehensive behavioral treatment, gradual weight regain is often observed overtime, resulting in modest ($5%) overall weight losses at 3 to 4 years.…”
Section: Effective Lifestyle Interventions For Weight Controlmentioning
confidence: 99%
“…Postpartum women face several challenges to attending traditional face-to-face weight loss interventions; this may explain the high attrition rates (30-40%) seen in many postpartum weight loss programs. [135][136][137][138] Delivering weight loss intervention via telephone and/or other modalities (i.e., internet and mobile technology) may offer an alternative to face-to-face interventions 68 and may be particularly useful for postpartum women. 139 Regardless of modality, sufficient "dose" of treatment and incorporation of evidence-based weight control strategies are likely more important in determining postpartum intervention efficacy.…”
Section: Future Directionsmentioning
confidence: 99%
“…139 Regardless of modality, sufficient "dose" of treatment and incorporation of evidence-based weight control strategies are likely more important in determining postpartum intervention efficacy. 68…”
Gestational diabetes mellitus (GDM) is linked with several acute maternal health risks and long-term development of type 2 diabetes, metabolic syndrome, and cardiovascular disease. Intrauterine exposure to GDM similarly increases offspring risk of early life health complications and later disease. GDM recurrence is common, affecting 40–73% of women, and augments associated maternal/fetal/child health risks. Modifiable and independent risk factors for GDM include maternal excessive gestational weight gain and pre-pregnancy overweight and obesity. Lifestyle interventions that target diet, activity, and behavioral strategies can effectively modify adiposity. Randomized clinical trials testing the effects of lifestyle interventions during pregnancy to reduce excessive gestational weight gain have generally shown mixed effects on reducing GDM incidence. Trials testing the effects of postpartum lifestyle interventions among women with a history of GDM have shown reduced incidence of diabetes and improved cardiovascular disease risk factors. However, the long-term effects of inter-pregnancy or pre-pregnancy lifestyle interventions on subsequent GDM remain unknown. Future adequately powered and well-controlled clinical trials are needed to determine the effects of lifestyle interventions to prevent GDM and identify pathways to effectively reach reproductive-aged women across all levels of society, before, during, and after pregnancy.
“…Moreover, treatment can be delivered over many modalities (in-person, phonebased, and internet). 68 Clinical trials testing the effects of comprehensive behavioral programs have found weight losses averaging $10.7 kg (11% of body weight) over 30 weeks. 66,69 Nonetheless, even with comprehensive behavioral treatment, gradual weight regain is often observed overtime, resulting in modest ($5%) overall weight losses at 3 to 4 years.…”
Section: Effective Lifestyle Interventions For Weight Controlmentioning
confidence: 99%
“…Postpartum women face several challenges to attending traditional face-to-face weight loss interventions; this may explain the high attrition rates (30-40%) seen in many postpartum weight loss programs. [135][136][137][138] Delivering weight loss intervention via telephone and/or other modalities (i.e., internet and mobile technology) may offer an alternative to face-to-face interventions 68 and may be particularly useful for postpartum women. 139 Regardless of modality, sufficient "dose" of treatment and incorporation of evidence-based weight control strategies are likely more important in determining postpartum intervention efficacy.…”
Section: Future Directionsmentioning
confidence: 99%
“…139 Regardless of modality, sufficient "dose" of treatment and incorporation of evidence-based weight control strategies are likely more important in determining postpartum intervention efficacy. 68…”
Gestational diabetes mellitus (GDM) is linked with several acute maternal health risks and long-term development of type 2 diabetes, metabolic syndrome, and cardiovascular disease. Intrauterine exposure to GDM similarly increases offspring risk of early life health complications and later disease. GDM recurrence is common, affecting 40–73% of women, and augments associated maternal/fetal/child health risks. Modifiable and independent risk factors for GDM include maternal excessive gestational weight gain and pre-pregnancy overweight and obesity. Lifestyle interventions that target diet, activity, and behavioral strategies can effectively modify adiposity. Randomized clinical trials testing the effects of lifestyle interventions during pregnancy to reduce excessive gestational weight gain have generally shown mixed effects on reducing GDM incidence. Trials testing the effects of postpartum lifestyle interventions among women with a history of GDM have shown reduced incidence of diabetes and improved cardiovascular disease risk factors. However, the long-term effects of inter-pregnancy or pre-pregnancy lifestyle interventions on subsequent GDM remain unknown. Future adequately powered and well-controlled clinical trials are needed to determine the effects of lifestyle interventions to prevent GDM and identify pathways to effectively reach reproductive-aged women across all levels of society, before, during, and after pregnancy.
“…The authors concluded, however, that longer, pragmatic, interdisciplinary, open-source interventions are needed. In a similar way, meta-analyses performed by Neve et al [ 22 ], Manzoni et al [ 23 ], Kodama et al [ 24 ], and Dutton et al [ 25 ] found that Internet use in obesity treatment programmes has a modest but significant effect on weight control. These reviews also point out variations between trials (with smaller effect sizes, and inconsistent findings across studies), mixed results, heterogeneity of designs, and low generalization of the findings, however, and they emphasise that better descriptions of components of effective interventions are still needed.…”
BackgroundThe prevalence of overweight and obesity is on the rise worldwide with severe physical and psychosocial consequences. One of the most dangerous is hypertension. Lifestyle changes related to eating behaviour and physical activity are the critical components in the prevention and treatment of hypertension and obesity. Data indicates that the usual procedures to promote these healthy habits in health services are either insufficient or not efficient enough. Internet has been shown to be an effective tool for the implementation of lifestyle interventions based on this type of problem. This study aims to assess the efficacy of a totally self-administered online intervention programme versus the usual medical care for obese and overweight participants with hypertension (from the Spanish public health care system) to promote healthy lifestyles (eating behaviour and physical activity).MethodA randomized controlled trial will be conducted with 100 patients recruited from the hypertension unit of a public hospital. Participants will be randomly assigned to one of two conditions: a) SII: a self-administered Internet-based intervention protocol; and b) MUC-medical usual care. The online intervention is an Internet-delivered, multimedia, interactive, self-administered programme, composed of nine modules designed to promote healthy eating habits and increase physical activity. The first five modules will be activated at a rate of one per week, and access for modules 5 to 9 will open every two weeks. Patients will be assessed at four points: before the intervention, after the intervention (3 months), and at 6 and 12 months (follow-up). The outcome variables will include blood pressure, and Body Mass Index, as primary outcome measures, and quality of life and other lifestyle and anthropometrical variables as secondary outcome measures.DiscussionThe literature highlights the need for more studies on the benefits of using the Internet to promote lifestyle interventions. This study aims to investigate the efficiency of a totally self-administered Internet − +based programme for promoting healthy habits and improving the medical indicators of a hypertensive and overweight population.Trial registrationNCT02445833
“…Overall 20/28 of the studies demonstrated cost-effectiveness of an intervention, but we cannot rule out publication bias skewing our results towards including studies demonstrating cost-effectiveness. However, the share of studies reporting (cost) effectiveness is similar to comparable reviews in the field [ 56 ].…”
BackgroundCountries of the Asia Pacific region account for a major share of the global burden of disease due to cardiovascular disease (CVD) and this burden is rising over time. Modifiable behavioural risk factors for CVD are considered a key target for reduction in incidence but their effectiveness and cost-effectiveness tend to depend on country context. However, no systematic assessment of cost-effectiveness of interventions addressing behavioural risk factors in the region exists.MethodsA systematic review of the published literature on cost-effectiveness of interventions targeting modifiable behavioural risk factors for CVD was undertaken. Inclusion criteria were (a) countries in Asia and the Pacific, (b) studies that had conducted economic evaluations of interventions (c) published papers in major economic and public health databases and (d) a comprehensive list of search words to identify appropriate articles. All authors independently examined the final list of articles relating to methodology and findings.ResultsUnder our inclusion criteria a total of 28 studies, with baseline years ranging from 1990 to 2012, were included in the review, 19 conducted in high-income countries of the region. Reviewed studies assessed cost-effectiveness of interventions for tobacco control, alcohol reduction, salt intake control, physical activity and dietary interventions. The majority of cost-effectiveness analyses were simulation analyses mostly relying on developed country data, and only 6 studies used effectiveness data from RCTs in the region. Other than for Australia, no direct conclusions could be drawn about cost-effectiveness of interventions targeting behavioural risk factors due to the small number of studies, interventions that varied widely in design, and varied methods for measurement of costs associated with interventions.ConclusionsGood quality cost-effectiveness information on interventions targeting behavioural interventions for the Asia-Pacific region remains a major gap in the literature.Electronic supplementary materialThe online version of this article (doi:10.1186/s12992-014-0079-3) contains supplementary material, which is available to authorized users.
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