Mathematical Analysis of a Chlamydia Epidemic Model with Pulse Vaccination Strategy

Samanta, G. P.

doi:10.1007/s10441-014-9234-8

Cited by 15 publications

(11 citation statements)

References 45 publications

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“…Studies analyzing mathematical models for STDs addressing important epidemiological implications have been reported [15][16][17][18][19]. Mathematical models could provide additional insights in disease epidemiology with the ultimate goal of formulating preventive measures for halting the rise in sexually transmitted infections.…”

Section: Adolescent Pregnancy and Risks For Congenital Syphilismentioning

confidence: 99%

It Is Complicated: The Medico-Social Journey of an Undocumented Pregnant Adolescent

Kest¹,

Kaushik

Tehreem³

et al. 2020

Case Reports in Pediatrics

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Adolescent pregnancies are a global health problem with over 16 million children born to this age group globally. Adolescent females also represent almost half of all adolescent global migrants. Adolescent pregnancy by itself is associated with poor health care access and morbidities; the additional risk of social insecurity in the case of undocumented adolescent migrants leads to higher risks for the mother and newborn. According to the CDC, adolescents comprise half of all new sexually transmitted diseases (STDs) including reported primary and secondary syphilis. Our case highlights the relationship between social insecurity for the undocumented adolescent migrant and excess risks for preventable mother-to-child transmission of communicable diseases. In formulating preventive measures and policies for the recent rise in sexually transmitted maternal diseases with resultant congenital infections, there is need for health care systems and providers to familiarize themselves with advocacy and other useful resources that will promote health care access for undocumented and other vulnerable adolescents. Additionally, local providers who work in areas with a large population of immigrant adolescents should utilize the untapped resources of these adolescents to develop youth community advocacy projects that link adolescents to health resources, including reproductive health.

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Section: Adolescent Pregnancy and Risks For Congenital Syphilismentioning

confidence: 99%

It Is Complicated: The Medico-Social Journey of an Undocumented Pregnant Adolescent

Kest¹,

Kaushik

Tehreem³

et al. 2020

Case Reports in Pediatrics

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“…They showed that stratifying the Chlamydia trachomatis model, based on the risk of acquiring or transmitting infection, induced the phenomenon of backward bifurcation even when the re-infection of recovered individuals did not occur. Samanta [32] developed a mathematical model for Chlamydia with pulse vacciantion strategy. He showed using simulations with MATLAB, the conditions under which the disease will go into extinction and when the disease will persist in the population.…”

Section: Introductionmentioning

confidence: 99%

Optimal Control and Cost-Effectiveness Analysis of an HPV–Chlamydia trachomatis Co-infection Model

2021

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In this work, a co-infection model for human papillomavirus (HPV) and Chlamydia trachomatis with cost-effectiveness optimal control analysis is developed and analyzed. The disease-free equilibrium of the co-infection model is shown not to be globally asymptotically stable, when the associated reproduction number is less unity. It is proven that the model undergoes the phenomenon of backward bifurcation when the associated reproduction number is less than unity. It is also shown that HPV re-infection (ε p = 0) induced the phenomenon of backward bifurcation. Numerical simulations of the optimal control model showed that: (i) focusing on HPV intervention strategy alone (HPV prevention and screening), in the absence of Chlamydia trachomatis control, leads to a positive population level impact on the total number of individuals singly infected with Chlamydia trachomatis, (ii) Concentrating on Chlamydia trachomatis intervention controls alone (Chlamydia trachomatis prevention and treatment), in the absence of HPV intervention strategies, a positive population level impact is observed on the total number of individuals singly infected with HPV. Moreover, the strategy that combines and implements HPV and Chlamydia trachomatis prevention controls is the most cost-effective of all the control strategies in combating the co-infections of HPV and Chlamydia trachomatis.

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“…Mathematical models have become important tools in studying the behaviour of infectious diseases [14,15,16,17,18,19,20,21,22,23]. Mathematical models have also been developed to understand the dynamics of Chlamydia trachomatis, gonorrhea or their co-infections [24,25,26,27,28,29,30]. For instance, Gkana and Zachilas [24] developed a deterministic epidemic model for the spread of gonorrhea.…”

Section: Introductionmentioning

confidence: 99%

Mathematical Analysis of a model for Chlamydia and Gonorrhea Codynamics with Optimal Control

Chukukere

Inyama

Omame

2020

Preprint

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A model for Chlamydia trachomatis (CT) and Gonorrhea codynamics, with optimal control analysis is studied and analyzed to assess the impact of targetted treatment for each of the diseases on their co-infections in a population. The model exhibits the dynamical feature of backward bifurcation when the associated reproduction number is less than unity. The global asymptotic stability of the disease-free equilibrium of the co-infection model is also proven not to exist, when the associated reproduction number is below unity. The necessary conditions for the existence of optimal control and the optimality system for the co-infection model is established using the Pontryagin's Maximum Principle. Simulations of the optimal control model reveal that the intervention strategy which implements female Chlamydia trachomatis treatment and male gonorrhea treatment is the most effective in combating the co-infections of Chlamydia trachomatis and gonorrhea.

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Mathematical Analysis of a Chlamydia Epidemic Model with Pulse Vaccination Strategy

Cited by 15 publications

References 45 publications

It Is Complicated: The Medico-Social Journey of an Undocumented Pregnant Adolescent

It Is Complicated: The Medico-Social Journey of an Undocumented Pregnant Adolescent

Optimal Control and Cost-Effectiveness Analysis of an HPV–Chlamydia trachomatis Co-infection Model

Mathematical Analysis of a model for Chlamydia and Gonorrhea Codynamics with Optimal Control

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