Same-day and delayed reports of pain intensity in second-trimester medical termination of pregnancy: a brief report

Abstract

Adequate, properly timed pain management during second-trimester MTOP is crucial.

Patient-controlled intravenous versus on-demand oral, intramuscular or mcs intravenous administration of oxycodone during medical induced abortion from 64 to 128 days of Gestation: A randomized controlled trial

“…[9] Reported need for additional narcotic analgesics for pain control during second-trimester medical abortion has varied from less than 10% to more than 80% in different studies. [1,7,9,10] Oxycodone taken orally at onset of abdominal pain did not reduce maximal pain during medical abortion at less than 11 weeks of pregnancy compared to placebo. [8] Study on intravenous patient-controlled analgesia (IVPCA) with different fentanyl doses compared to morphine showed a fentanyl dose 50ug to be most effective.…”

“…In an earlier study, we reported mean maximal pain VAS of 70 (SD26.5) during second-trimester medical abortion. [7] The study hypothesis was that we can decrease the pain level from VAS 70 to 35 by means of IVPCA. We initially planned to recruit participants in four subgroups of different gestational age and age: late-first-and second-trimester abortions, and teenagers and adult participants separately (ratio 1:2).…”

“…VAS >7, on scale 1-10). [1,[7][8][9] Advanced duration of gestation, nulliparity, younger age and history of dysmenorrhea predict a more intense pain experience. [4,10] Often the most severe pain is related to fetal expulsion, occurring within few hours after initiation of misoprostol administration.…”

“…[4,10] Often the most severe pain is related to fetal expulsion, occurring within few hours after initiation of misoprostol administration. [7,8] Knowledge on optimal pain management during late-first-and second-trimester medical abortion is lacking and practice varies between providers. [11][12][13] The use of non-steroidal anti-inflammatory drugs (NSAIDs) does not interfere with the effect of mifepristone or misoprostol, and prophylactic use of NSAIDs lowers the need for opiates during medical abortion.…”

The Lighter Side of Pain: Do Positive Affective States Predict Memory of Pain Induced by Running a Marathon?

“…1 This also applies to pain recollection. Previous studies show that both acute [2][3][4][5][6][7][8][9] and chronic pain [10][11][12] might be misremembered. Moreover, the current literature also shows that the way in which pain is remembered influences subsequent pain experiences, [13][14][15] as well as future decisions to engage in activities that may be accompanied by pain.…”