Treatment of complex infantile haemangioma in a resource-poor setting

Abstract

Infantile haemangiomas affect approximately 5% of the population and usually do not require treatment. However, complex cutaneous haemangiomas can cause disabling disfigurement, while haemangiomas in the brain, airway or gastrointestinal tract can cause life-threatening complications. Although children with infantile haemangiomas are often first brought to general practitioners and paediatricians by parents for care, they are thought of as a surgical problem and usually referred to specialty care. We present a case of an infant from a resource-poor setting in rural Indonesia with disfiguring facial haemangiomas, as well as a probable airway haemangioma causing stridor at rest. The infant was treated with oral propranolol with marked involution of the cutaneous haemangioma, resolution of stridor and increase in weight.

Hemangiomas of Abdominal Organs in Children

“…Гемангиомы могут быть небольшими и могут достигать очень больших размеров, быть красного, синего цвета, бугристыми, консистенция плотная или мягко-эластичная. Достигая больших размеров гемангиома печени вы-зывает у детей чувство тяжести в эпигастральной области, общую слабость, иногда рвоту [10][11][12]…”

Use of Propranolol in Infantile Hemangioma Resulting in Scarless Healing

“…5 Thus, the timely recognition and therapy are paramount to achieve minimal scarring and complication. 5,6 Over the last few years, propranolol has gained popularity since was found accidentally while treating cardiovascular disease, 7 and has been recommended as a first-line therapy in the management of proliferating IHs in some centers, especially when involving the airway. 7,8,9 It may exert its effects on growing hemangiomas by three different molecular mechanisms: vasoconstriction, inhibition of angiogenesis, and induction of apoptosis, especially during hypoxia.…”