Primary pancreatic leiomyosarcoma: a rare diagnosis obtained by EUS-FNA cytology

Hébert‐Magee, Shantel; Varadarajulu, Shyam; Frost, Andra R.; Ramesh, Jayapal

doi:10.1016/j.gie.2014.02.030

Cited by 10 publications

(16 citation statements)

References 2 publications

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“…8 The mean age is 53.9 614.7 years old (range 5 14-87 years) with an equal incidence among males and females. 2,3,6,7,9,10 The majority of cases are located in the head of the pancreas. 2,3,6,7,9,10 The majority of cases are located in the head of the pancreas.…”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5][9][10][11][12] Patients with metastasis undergo biopsy only or palliative procedures. 7 Many case reports show remission after complete resection, 3,5,[9][10][11][12] with the longest remission lasting > 20 years. 7 Many case reports show remission after complete resection, 3,5,[9][10][11][12] with the longest remission lasting > 20 years.…”

Section: Discussionmentioning

confidence: 99%

“…1 They are the most common primary pancreatic sarcoma 2 and are thought to originate from the pancreatic duct or blood vessels within the pancreas. 7 We are reporting a second case of a primary pancreatic leiomyosarcoma with metastasis to the liver that yielded diagnostic material on EUS-FNA. One case in the literature has documented a successful attempt to diagnose a primary pancreatic leiomyosarcoma by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and cytology.…”

mentioning

confidence: 99%

“…One case in the literature has documented a successful attempt to diagnose a primary pancreatic leiomyosarcoma by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and cytology. 7 We are reporting a second case of a primary pancreatic leiomyosarcoma with metastasis to the liver that yielded diagnostic material on EUS-FNA. Diagnosis was made by EUS-FNA and EUS fine needle biopsy.…”

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confidence: 99%

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Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound‐guided fine needle aspiration and fine needle biopsy

Reyes

Huang

Bain

et al. 2016

Diagnostic Cytopathology

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Primary pancreatic leiomyosarcomas are rare tumors of the pancreas that are usually diagnosed after resection or by biopsy. One case in the literature has utilized endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology. We report a second case of a primary pancreatic leiomyosarcoma that yielded diagnostic material on EUS-FNA cytology. A 72-year-old female presented with 3-4 months of abdominal pain. A CT scan showed a large heterogeneous, lobulated pancreatic head and uncinate mass and multiple hypoattenuating liver lesions. An EUS-FNA was performed on one of the liver lesions with a 25-gauge needle, yielding an adequate sample with lesional cells. The initial read was a spindle cell neoplasm. A subsequent endoscopic ultrasound-guided fine needle biopsy with a 22-gauge needle was performed on the pancreatic head mass to rule out two primaries and to provide tissue for a mitotic index in the case of gastrointestinal tumor. Both the cell block of the EUS-FNA and the core biopsy were equally cellular and showed interlacing spindle cells that stained positive for SMA and negative for DOG-1, CD 117, and CD34. In addition, the core biopsy of the pancreas stained positive for Desmin. A diagnosis of a primary pancreatic leiomyosarcoma was made and the patient was started on systemic chemotherapy. Primary pancreatic leiomyosarcomas are rare pancreatic tumors that may yield diagnostic material by EUS-FNA with a 25-gauge needle. Diagn. Cytopathol. 2016;44:1070-1073. © 2016 Wiley Periodicals, Inc.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound‐guided fine needle aspiration and fine needle biopsy

Reyes

Huang

Bain

et al. 2016

Diagnostic Cytopathology

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“…Only a handful of case reports where diagnosis was based on EUS FNA are available in literature. 5,6 EUS provides an ideal window to target lesions in the pancreas. Although most lesions in pancreas are adenocarcinoma, SCL forms a rare distinct category, which may be encountered by cytologists in practise.…”

Section: On 13mentioning

confidence: 99%

Metastatic leiomyosarcoma to the pancreas diagnosed on endoscopic ultrasound‐guided fine needle aspiration – A report of two cases with review of spindle cell lesions of pancreas

2020

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Leiomyosarcoma Involving the Pancreas Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration

Abdelfatah

Gochanour

2016

J Gastrointest Canc

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Primary pancreatic leiomyosarcoma: a rare diagnosis obtained by EUS-FNA cytology

Cited by 10 publications

References 2 publications

Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound‐guided fine needle aspiration and fine needle biopsy

Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound‐guided fine needle aspiration and fine needle biopsy

Metastatic leiomyosarcoma to the pancreas diagnosed on endoscopic ultrasound‐guided fine needle aspiration – A report of two cases with review of spindle cell lesions of pancreas

Leiomyosarcoma Involving the Pancreas Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration

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