25-Hydroxycholecalciferol in Chronic Renal Failure

Lund, B.; Oh, Sørensen; Sp, Nielsen; Munck, O.; Bärenholdt, O.; Petersen, Karsten

doi:10.1016/s0140-6736(75)92822-6

Cited by 8 publications

(1 citation statement)

References 5 publications

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“…A defective function of its activity due to parenchymal loss may be another reason for decreased concentration of 1, 25(OH)2D in the circulation as indicated by a positive correlation between serum 1, 25(OH)2D and creatinine (Schaefer et al, 1978). Also 25 OH D is reported to be low in these patients (Mason et al, 1979;Offermann et al, 1974), although Lund et al (1975) and Jongen et al (1984) report about elevated and slightly elevated levels, respectively. Patients with chronic renal failure are found to have hypocalcemia and secondary hyperparathyroidism.…”

Section: Discussionmentioning

confidence: 81%

Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin in Chronic Renal Failure

Franck

Keck

Issa

et al. 2009

Exp Clin Endocrinol Diabetes

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Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) is normal in some patients with chronic renal failure. We studied the question, whether factors known to regulate the serum 1,25(OH)2D concentration such as parathyroid hormone, calcium, phosphate and especially the serum 25 hydroxy vitamin D (25 OH D) concentration are related to circulating levels of serum 1,25(OH)2D in such patients. We found no correlation between these serum parameters and 1,25(OH)2D. Our data indicate that other factors are of more importance for the regulation of serum 1,25(OH)2D in this situation.

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Section: Discussionmentioning

confidence: 81%