Fungal Endocarditis Observed Over an 8-Year Period and a Review of the Literature

Antinori, Spinello; Ferraris, Laurenzia; Orlando, Giovanna; Tocalli, Loredana; Ricaboni, Davide; Corbellino, Mario; Sollima, Salvatore; Galli, Massimo; Milazzo, Laura

doi:10.1007/s11046-014-9754-4

Cited by 38 publications

(34 citation statements)

References 53 publications

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“…The yeast identification is ideal for the management of fungal endocarditis (FE) [ 3, 4 ]. The widespread prophylaxis and the empirical treatment of fungemia with triazole antifungal agents may also allow the emergence of specifically resistant fungi, including Rhodotorula species, due to its natural resistance to fluconazole and echinocandins [ 2, 5 ].…”

Section: Discussionmentioning

confidence: 99%

Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature

et al. 2017

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Introduction. Endocarditis caused by yeasts is currently an emerging cause of infective endocarditis and, when accompanied byfever of unknown origin, is more severe since interferes with proper diagnosis and endocarditis treatment.Case presentation. The Rio de Janeiro Infective Endocarditis Study Group reports a case of infectious endocarditis (IE) with negative blood cultures in a 45-year-old white female resident in Rio de Janeiro, Brazil, previously submitted to kidney transplantation. After diagnosis and intervention, the valve culture revealed Rhodotorula mucilaginosa. The clinical aspects and overview of endocarditis caused by Rhodotorula spp. demonstrated that R. muscilaginosa have been isolated from the last IE cases from kidney transplanted patients.Conclusion. Though most of the patients (in literature) recovered well from endocarditis caused by Rhodotorula spp., physicians must be aware for diagnosis of fungemia and fungal treatment in kidney transplanted patients suffering of fever of unknown origin in the modern immunosuppressive treatment.

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Section: Discussionmentioning

confidence: 99%

Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature

et al. 2017

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“…However, despite the radical surgical strategy, a recurrence rate of up to 40% is observed and has a dismal prognosis. It is not clear when the surgery should be performed [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Rapid Fulminant Case of Aspergillus Prosthetic Valve Endocarditis

Ortega-Loubón

Fernández-Molina

Tobar-Ruiz

et al. 2017

Cureus

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“…[8,7] However, echocardiographic evidence of endocardial involvement can throw suspicion on endocarditis and lead to diagnosis. [9] Transthoracic and transesophageal echocardiography has been shown to be useful in diagnosing fungal infections of the heart and sensitivity of these methods are quite similar, 88.9% and 92%, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…[10,11,9] In most cases, diagnosed as FE, clinical presentations are large vegetations seen in echocardiography and the absence of positive blood cultures for typical bacterial agents. [5] In our case, an evident mass in right atrium, originating from right side of atrial septum and extanding to right ventricular cavity through tricuspit valve was detected in transthoracic echocardiography.…”

Section: Discussionmentioning

confidence: 99%

Right atrial aspergilloma mimicking atrial mixomax

Kolbakir¹,

Balaban²,

Baysal³

2016

ejcm

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Infective endocarditis is a serious but relatively rare infection that is associated with high morbidity and mortality rates. Aspergillus endocarditis is an uncommon entity and invasive cardiac aspergillosis is a severe and extremely life threatening disease. Prolonged use of intravascular catheters, anatomical cardiac conditions, exposure to multiple broad-spectrum antibiotics, intravenous drug abuse, and previous history of surgery are the most common risk factors of fungemia and fungal endocarditis. Diagnosis is based on the isolation of etiologic agents from cardiac and blood samples or specimens from other sterile sites or positive histopathological findings of pathologic specimens. Echocardiographic findings of endocardial involvement can lead to diagnosis. Echocardiographically, differencial diagnosis of tumor extensions, especially myxoma, atipically located bacterial vegetations, thrombus or fungal masses is very difficult as thrombi and infective verrus can mimic myxomas. Treatment of fungal endocarditis only with antifungal agents is generally unsuccessful and additional surgical intervention is usually required. In this case report we present an fungal endocarditis caused by Aspergillus species that mimicked an atrial myxoma echocardiographically in a patient who had a history of treatment with wide spectrum antibiotics for a long time. We suggest that patients who had broad spectrum antibiotic treatment for a long time should be scanned for fungal infections and if intracardiac mass is determined, fungal endocarditis should be considered in differential diagnosis. Keywords:

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Fungal Endocarditis Observed Over an 8-Year Period and a Review of the Literature

Abstract: FE is difficult to diagnose but generally associated with healthcare infections. The optimal treatment is poorly characterised, and international collaborative studies are urgently needed to evaluate newer antifungal agents.

Cited by 38 publications

References 53 publications

Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature

Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature

Rapid Fulminant Case of Aspergillus Prosthetic Valve Endocarditis

Right atrial aspergilloma mimicking atrial mixomax

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