Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE)

Jutila, Leena; Äikiä, Marja; Immonen, Arto; Mervaala, Esa; Alafuzoff, Irina; Kälviäinen, Reetta

doi:10.1016/j.eplepsyres.2014.05.002

Cited by 13 publications

(5 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most studies are in agreement that on long-term follow-up, verbal memory impairment occurs postoperatively in left-sided (or in both left- and right-sided) surgeries [13,14]. Visual memory measures either slightly deteriorate or remain stable after right-sided operations [41]. On the long-term follow-up, there is no agreement whether postoperative verbal memory impairments that occur early after operation further decline [30] or remain stable.…”

Section: Discussionmentioning

confidence: 53%

Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study

Krámská¹,

Vojtěch²,

Lukavský³

et al. 2017

Stereotact Funct Neurosurg

View full text Add to dashboard Cite

Purpose: To assess the neuropsychological performance recoded over a period of 5 years after stereotactic radiofrequency amygdalohippocampectomy (SAHE) in the treatment of mesial temporal lobe epilepsy. Material and Methods: Thirty patients (mean age 38 years, 14 females/16 males) were included in this study. Twenty-one patients were treated on the left side, 9 on the right. Patients underwent neuropsychological evaluation by the Wechsler Adult Intelligence Scale-Revised and the Wechsler Memory Scale-Revised preoperatively and 5 years after SAHE. Results: Twenty-three (77%) patients were classified as Engel class I. At the group level, we found significant increases in all intelligence domains (Global, Visual, and Performance) by 19.1 (7.4), 15.8 (6.1), and 19.1 (7.9) points, respectively. Significant improvements were also detected in all memory measures (Global, Verbal, Visual, Attention/Concentration, Delayed Recall) by 19.4 (14.2), 16.9 (13.3), 19.0 (14.7), 15.3 (15.0), and 24.6 (13.4), respectively. Patients with left-sided surgery improved significantly more in Attention/Concentration. Otherwise, there were no statistically significant differences in memory function improvements between subgroups according to the operated side. Conclusion: After SAHE, we found favorable long-term neuropsychological outcomes. These results could be caused by incomplete destruction of target structures and minimization of collateral damage that possibly enables adaptive postoperative neuronal reorganization.

show abstract

Section: Discussionmentioning

confidence: 53%

Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study

Krámská¹,

Vojtěch²,

Lukavský³

et al. 2017

Stereotact Funct Neurosurg

View full text Add to dashboard Cite

show abstract

“…However, risk for memory impairment remains to be considered as a serious post-surgical result. So far, long-term neuropsychological outcomes following TLE surgery have been reported by various prospective studies [ 19 , 20 ]. Given that few reports have focused on the long-term neuropsychological consequences of TLE surgery, we attempted to provide a review of the literature, investigating neuropsychological function of adult patients undergoing resective TLE surgery and followed for a mean/median > five years period.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Neuropsychological Outcomes Following Temporal Lobe Epilepsy Surgery: An Update of the Literature

et al. 2021

View full text Add to dashboard Cite

We present an update of the literature concerning long-term neuropsychological outcomes following surgery for refractory temporal lobe epilepsy (TLE). A thorough search was conducted through the PubMed and Medline electronic databases for studies investigating neuropsychological function in adult patients undergoing resective TLE surgery and followed for a mean/median > five years period. Two independent reviewers screened citations for eligibility and assessed relevant studies for the risk of bias. We found eleven studies fulfilling the above requirements. Cognitive function remained stable through long-term follow up despite immediate post-surgery decline; a negative relation between seizure control and memory impairment has emerged and a possible role of more selective surgery procedures is highlighted.

show abstract

“…Los pacientes que no deterioraron tenían un nivel de activación preoperatoria mayor que el resto, lo cual indicaría que una reorganización de la memoria de modo precoz en el contexto preoperatorio en la región posterior del hipocampo ipsilateral sería eficiente y protectora, mientras que la reorganización temprana tras la cirugía, pero sin existir previamente, no podría mantener la función 15 . Los autores también observan, sin embargo, que el tiempo de seguimiento de los pacientes podría ser demasiado corto para evidenciar el papel de la reserva funcional, ya que los cambios de la memoria son dinámicos en el tiempo 12,35 , lo que podría explicar las diferencias observadas con otros estudios de seguimiento a largo plazo mediante RMf, donde la función de memoria posquirúrgica se asociaba con la activación mesiotemporal contralateral al lado de la cirugía 41 .…”

Section: Discussionunclassified

Evaluación de la memoria en la epilepsia del lóbulo temporal para predecir sus cambios tras la cirugía. Una revisión sistemática

Parra‐Díaz

García‐Casares

2019

Neurología

View full text Add to dashboard Cite

show abstract

Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE)

Cited by 13 publications

References 46 publications

Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study

Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study

Long-Term Neuropsychological Outcomes Following Temporal Lobe Epilepsy Surgery: An Update of the Literature

Evaluación de la memoria en la epilepsia del lóbulo temporal para predecir sus cambios tras la cirugía. Una revisión sistemática

Contact Info

Product

Resources

About