249 FCRN-mediated pulmonary delivery of interferon alpha FC-fusion protein in non-human primates

Palombella, Vito J.; Boudreau, Denis; Garcia, Alina V.; Kropp, K; Low, Susan C.; Lu, Yanmei; Morris, Kevin V.; Peters, Robert; Stattel, James Michael Walker; Dumont, Jennifer

doi:10.1016/s0270-9139(03)80292-6

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Oral Uptake Via the Intestinal Fcrn Receptor1

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2011

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“…The receptor appears to occur on the major mucosal sites and the FcRn appears to be rela tively conserved across the species as it has been found in the lungs of humans and nonhuman primates [210][211][212][213][214][215][216][217] and in the lung of rats [218] and the human female genital tract [219].…”

Section: Oral Uptake Via the Intestinal Fcrn Receptormentioning

confidence: 99%

Intestinal Receptor Targeting for Peptide Delivery: an expert‘s Personal Perspective on Reasons for Failure and New Opportunities

Russell‐Jones

2011

Therapeutic Delivery

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The technology has been available more than 25 years that would enable the oral delivery of vaccines, proteins and peptides, thus avoiding the need for injection. To this day, injection is still the mode of delivery, yet not the main mode of choice. This review focuses on several of the potential modes for oral delivery of peptides, proteins and vaccines. Additionally, the review will provide the reader with an insight into the problems and potential solutions for several of these modes of oral delivery of peptides and proteins.

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Section: Oral Uptake Via the Intestinal Fcrn Receptormentioning

confidence: 99%

Intestinal Receptor Targeting for Peptide Delivery: an expert‘s Personal Perspective on Reasons for Failure and New Opportunities

Russell‐Jones

2011

Therapeutic Delivery

View full text Add to dashboard Cite

show abstract

249 FCRN-mediated pulmonary delivery of interferon alpha FC-fusion protein in non-human primates

Cited by 1 publication

References 0 publications

Intestinal Receptor Targeting for Peptide Delivery: an expert‘s Personal Perspective on Reasons for Failure and New Opportunities

Intestinal Receptor Targeting for Peptide Delivery: an expert‘s Personal Perspective on Reasons for Failure and New Opportunities

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