The basics and advances of immunomodulators and antigen presentation: a key to development of potent memory response against pathogens

Abstract

Understanding the molecular mechanisms underlying immune response is a prerequisite for development of effective therapeutics as these are often exploited by pathogens for their own propagation. Keeping this in mind, the present research in the field of immunotherapy focuses on developing immunomodulators that would not only enhance the protection against pathogen, but also generate a long-term memory response. With the introduction of advanced formulations including combination of different kinds of immunomodulators, one can expect tremendous success in near future.

Chitosan Nanoparticles for Generating Novel Systems for Better Applications: A Review

“…Earlier we had indicated liposomes and chitosan derived materials could be better delivery agents for novel vaccines [28]. Furthermore, our collaborator's work towards understanding the efficacy of Chitosan-dextran sulphate (CD) nanocapsules in delivering specific drugs against intracellular bacterial pathogens suggest that CD nanocapsules could effectively deliver specific antibiotics against intraphagosomal Salmonella leading to killing and clearing the pathogen [29].…”