Breast cancer: from Halsted to Harney

Kell, Malcolm R.

doi:10.1007/s11845-014-1142-z

Cited by 3 publications

(3 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, with the addition of radiation therapy in local disease treatment significant improvements were seen in the cancer regional control with several studies supporting these observations [12,13]. Generalized treatment pathways for both subtypes of stage III tumours can be seen in Fig 2. Currently the most common form of mastectomy performed in patient presenting with Tis-T3 tumours is the skin sparing mastectomy [15,16], which involves removing all breast tissue, the nipple-areolar complex, cicatrices of previous breast surgical procedures, interpectoral fascia and appropriate axillary lymph node investigation -ALND (lvl I-II) or a sentinel node biopsy, thus sparing both the pectoral muscles in addition to N. Thoracicus longus and N. Thoracodorsalis. This approach has demonstrated a recurrence rate of less than 7% in contrast to the long-term rate obtained by using the classical modified radical mastectomy [17].…”

Section: The Modified Radical Skin-sparing and Nipple-sparing Mastecmentioning

confidence: 99%

“…Interestingly, when ALND was first proposed, it was for therapeutic purposes however it soon became clear that the majority of woman who had presented with nodal involvement died of BC after undergoing local surgical therapy alone. As a result currently nodal assessment is utilized only for diagnostic, staging procedures to determine the extent of the disease (Fig 4) [16].…”

Section: Staging and Therapeutic Values Of Axillary Surgerymentioning

confidence: 99%

See 1 more Smart Citation

The Advancement and History of Breast Cancer Surgical Therapy at a Glance

Dimitrov¹,

Baytchev²,

Inkov³

et al. 2017

IJSM

View full text Add to dashboard Cite

For decades now breast cancer tissue resection has been the primary method of choice for treating the disease, however this was not the case throughout the history of medicine. For centuries breast cancer was considered to be incurable via surgical approaches and that only early, low grade, lesions can be removed safely. Not until the 19 th century, an increase in primary surgical therapy for the disease (mainly radical mastectomies) was becoming evident due to the teachings of Morgagni, in addition to a complete re-conceivement of the etiological process of the disease by Le Dran. Currently, practitioners have achieved a very high level of proficiency in treating the disease via continuous refinement of the aforementioned facts. This resulted in tissue and organ sparing local surgical approaches, including wide local excisions through para-areolar incisions and even skin and nipple-sparing mastectomies, which have long overpassed the unnecessary and primitive high morbidity approaches performed in the earlier attempts to treat breast cancer. KEYWORDS breast surgery techniques, breast cancer treatment, breast history Early history of breast cancer Currently, breast cancer (BC) surgical excision remains the gold standard for treating the disease and due to its significant social and economic impact, researchers and clinicians have attempted to identify the pathogenic processes giving rise to the disease. However it took centuries for medical practitioners to reach these conclusions. Nonetheless, even throughout the ages breast cancer has been capturing the attention of medicine and surgery practitioners universally, with the Smith Surgical Papyrus (3000-2500 b.c.

show abstract

Section: The Modified Radical Skin-sparing and Nipple-sparing Mastecmentioning

confidence: 99%

Section: Staging and Therapeutic Values Of Axillary Surgerymentioning

confidence: 99%

The Advancement and History of Breast Cancer Surgical Therapy at a Glance

Dimitrov¹,

Baytchev²,

Inkov³

et al. 2017

IJSM

View full text Add to dashboard Cite

show abstract

“…3 . A remoção da mama com extensa área de pele e a ressecção dos músculos peitorais seguida pela linfadenectomia axilar, podem ocasionar prejuízos na qualidade de vida das pacientes, devido à disfunção na motilidade do membro superior, surgimento de linfedema e danos aos nervos axilares4 .No início da década de 1970, foram iniciados estudos com o intuito de explorar se uma cirurgia menos agressiva poderia ser tão efetiva para as pacientes quanto a mastectomia5,6 . Veronesi et al e Fisher et al publicaram importantes casuísticas randomizadas, que incluíram pacientes submetidas à mastectomia radical ou ressecção segmentar mamária com dissecção linfonodal axilar completa (DLAC) e, demonstraram claramente, após mais de 20 anos de seguimento, que a cirurgia conservadora associada à radioterapia é tão eficaz quanto a cirurgia radical, em tumores medindo até 3,0 cm7,8 .…”

unclassified