Advanced Ovarian Dysgerminoma Infiltrating Both Ovaries and Uterus in a 7-Year-Old Girl

Abstract

Introduction. Ovarian dysgerminoma is a rare malignant ovarian germ cell tumor with its peak incidence in young women. Abdominal pain, abdominal distention, and the presence of a palpable mass are common symptoms at presentation. Depending on the FIGO stage at presentation the prognosis of dysgerminomas after surgical treatment, adjuvant chemotherapy, and radiotherapy is promising. Case Presentation. A 7-year-old girl was presented at our clinic with abdominal pain in all abdominal quadrants. Later the pain localized in the region of her right ovary. CT scan revealed a massive formation which was connected to her right ovary. Conclusion. Although malignant ovarian germ cell tumours are rare in children, physicians must always consider the possibility of MOGT-occurrences. The clinical symptoms might not be specific: abdominal pain, abdominal distention, nausea, and vomiting. In order to make a correct diagnosis the patients should undergo a complete clinical examination including radiological scans. Initial management is frequently surgery, followed by adjuvant chemotherapy and radiotherapy. Although disgerminoma is malignant tumor, the prognosis is promising.

A huge abdomino-pelvis tumour in a prepubertal girl: A case report of dysgerminoma infiltrating both ovaries and uterus in an 11-year-old girl in Maiduguri

“…The reason for that decision was a macroscopically visible infiltration of both ovaries and the uterus which coalesce to constitute the huge tumour mass. Although the main aim is fertility-preserving surgery and is possible in 70% of cases, 13,15 the indication for bilateral oophorectomy and hysterectomy in our case was inevitable. We could not see any remote possibility of sparing the infiltrated uterus and both ovaries without putting the child into risk of a further growing of the tumour and probably leading to metastasis into other organs and there by jeopardizing the survival of the child.…”

“…13 Lymph node metastasis is present in 28% of dysgerminomas and is significantly associated with poor survival. [15][16][17][18] In order to evaluate the prognosis and find adequate therapeutic options lymphadenectomy is indicated. The result of the lymphadenectomy in our case was negative for tumour cells.…”

Paediatric Ovarian Dysgerminoma: A Case Report

“…Clinical signs of dysgerminoma can range from asymptomatic, abdominal distension, abdomino-pelvic mass, ovarian torsion (adnexal torsion), monthly irregularities, vaginal bleeding, decreased appetite, nausea, vomiting or fever. 2 , 5 The tumoral mass often grows quickly and is usually quite large when it is diagnosed. 2 Similarly, in our case, the patient was asymptomatic and the tumour was quite large at the presentation to us.…”

Effusion Cytology of Dysgerminoma: A Case Report with Review of Literature

“…The average age is 22 years, and 90 percent of patients are less than 30 years of age. Clinical presentations vary from abdominal distension, abdominal mass to ovarian torsion [2]. Despite being of large sizes, ovarian tumors may still be confined to the ovaries however, omental, peritoneal and pleural spread of ovarian cancers has been reported which has a huge impact on prognosis and upstages prognostic morbidity [2,3].…”