Olfaction disorders: retrospective study✩✩Please cite this article as: Gregorio LL, Caparroz F, Nunes LM, Neves LR, Macoto EK. Olfaction disorders: retrospective study. Braz J Otorhinolaryngol. 2014;80:11-7.

Gregório, Luciano Lobato; Caparroz, Fábio de Azevedo; Nunes, Leonardo Mendes Acatauassu; Neves, Luciano Rodrigues; Kosugi, Eduardo Macoto

doi:10.5935/1808-8694.20140005

Cited by 7 publications

(2 citation statements)

References 23 publications

(41 reference statements)

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“…Two types of olfaction diseases are mainly described, qualitative and quantitative defects, with the latter more frequent, especially in older people, affecting from 3% to 20% of population [15,16]. A reduction or an impairment of the olfaction is reported to have a severe impact on quality of life [17]; olfaction provides different information, from the taste perception of food and drinks [18] to protection from dangers as burnings or gas leaks [19,20] and it is also fundamental for some professional figures like cooks, wine tasters, perfumers, nurses or firemen [17]. Olfactory dysfunction has been also related to scarce personal hygiene [21,22], impaired sex life [23], and limited emotional feelings [18].…”

Section: Discussionmentioning

confidence: 99%

Functional Magnetic Resonance Imaging in the Olfactory Perception of the Same Stimuli

Ciorba

Hatzopoulos

Cogliandolo

et al. 2020

Life

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Background. Data in the literature report that a number of studies have attempted to identify the exact location of the cortical olfaction representation, searching for evidence suggesting that sniffing odors can initiate a primary activation of the piriform cortex and the insula. Nowadays, due to the SARS-CoV-2 (COVID-19) outbreak, the functional study of the olfactory system could offer a better understanding of the physiopathology of olfactory perception, elucidating better the possible site(s) of damage induced by the COVID-19 infection. The aim of this paper was to evaluate brain maps generated from functional Magnetic Resonance Imaging (fMRI) data, collected from healthy individuals in response to the same olfactory stimulus. Methods. A total of 45 healthy volunteers, without history and/or no clinical signs of sinonasal disease and without history and/or presence of olfactory dysfunction underwent fMRI assessment. Subjects were presented with the same odorous stimuli at specific intervals. fMRI generated brain maps were used in the identification of different cortical areas, involved in the stimuli perception. Results. The fMRI brain maps showed that odorous stimuli activate primarily the left anterior insula (in 35/45 cases or 77.8%). Other activated areas include: the low temporal gyri, the middle and superior temporal gyri, the frontal and piriform cortex, the anterior cingulate gyrus, the parahippocampal gyrus, the temporopolar area, the para-insular area, the subcentral area, the supramarginal gyrus, the occipital cortex and the cerebellum. Conclusions. fMRI resulted as a safe and reliable means to study the perception of olfaction in the cortex. The data of this study suggest that the anterior insula is the main stimulated area when olfactory stimuli are present. This area is always activated, despite the hand and nostril dominance.

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Section: Discussionmentioning

confidence: 99%

Functional Magnetic Resonance Imaging in the Olfactory Perception of the Same Stimuli

Ciorba

Hatzopoulos

Cogliandolo

et al. 2020

Life

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“…alterações cardiovasculares e até mesmo transtornos do humor [1][2][3][4] . Existe uma longa lista de doenças, medicamentos e terapias que podem afetar o olfato e o paladar [5][6][7] . Recentemente, a radioterapia empregada no tratamento dos cânceres de cabeça e pescoço passou a fazer parte da lista de etiologias de distúrbios do sistema olfatório e gustatório 8,9 .…”

Section: Introductionunclassified

Distúrbios gustatórios em pacientes com câncer de cabeça e pescoço quando a radioterapia não inclui a cavidade oral

Silva¹

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Ao meu orientador, Prof. Dr. Fábio de Rezende Pinna, pela confiança. Seu apoio e incentivo foram fundamentais para o bom desenvolvimento dessa obra. Tê-lo-ei como modelo e espero tê-lo sempre como amigo.Ao Prof. Dr. Marco Aurélio Fornazieri, pela paciência, cordialidade e amizade. Seu profissionalismo, liderança, ética e simplicidade são fonte de inspiração para muitos jovens pesquisadores. A você devo parte desta minha vocação.

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Advances in Triboelectric Nanogenerators for Self‐Powered Regenerative Medicine

Parandeh

Etemadi

Kharaziha

et al. 2021

Adv Funct Materials

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Over the last decade, in pursuit to provide suitable alternatives for power supplies of medical devices in regenerative medicine, extensive research on nanogenerators has been developed. Such devices can overcome current commercial battery challenges, including intense heat-on-body complications due to the electrical current during therapeutic usage, leading to protein denaturation, cell structure destruction, and even cell necrosis. In addition, these traditional batteries contain a bulky and heavy structure that prevents them from providing sustainable on body biomedical therapeutic intervention. Furthermore, advantages such as wide-range biocompatible and biodegradable materials, lightweight, and sufficient stretchability for device construction can minimize the side effects of implantable devices, including inflammation or toxicity, as well as eliminate secondary surgery to replace or remove batteries. Triboelectric nanogenerators (TENGs) are associated with harvesting mechanical energy in various forms, among which human body motions can serve as a renewable power source for healthcare systems. This review is written to emphasize the importance of TENG's applications in regenerative medicine and modulation purposes, particularly for the nervous system. Some crucial parameters for implantable consideration are discussed. In the concluding remarks, features for clinical utilization including output efficiency, encapsulation, stability, and miniaturization are suggested as challenges and prospects.

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Olfaction disorders: retrospective study✩✩Please cite this article as: Gregorio LL, Caparroz F, Nunes LM, Neves LR, Macoto EK. Olfaction disorders: retrospective study. Braz J Otorhinolaryngol. 2014;80:11-7.

Abstract: Greater importance should be given to disorders of smell in practice of otolaryngologists, since its large differential diagnosis and the fact that could increase morbidity to patients, impacting on their quality of life.

Cited by 7 publications

References 23 publications

Functional Magnetic Resonance Imaging in the Olfactory Perception of the Same Stimuli

Functional Magnetic Resonance Imaging in the Olfactory Perception of the Same Stimuli

Distúrbios gustatórios em pacientes com câncer de cabeça e pescoço quando a radioterapia não inclui a cavidade oral

Advances in Triboelectric Nanogenerators for Self‐Powered Regenerative Medicine

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