2013
DOI: 10.1111/dth.12104
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Update on pediatric hyperhidrosis

Abstract: Hyperhidrosis is a common and under-recognized disease in the pediatric population that has a significant impact on quality of life. Focal and generalized forms of hyperhidrosis exist, which can be idiopathic or secondary to underlying medical conditions or medications. Treatment is tailored to the specific patient needs, characteristics and goals. These include topical preparations, iontophoresis, botulinum toxin and anticholinergic medications.

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Cited by 18 publications
(10 citation statements)
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“…In pediatric patients, HH affects 1.6% of adolescents and 0.6% of prepubertal children [ 20 ], and it remains widely undertreated. However, BoNT has been demonstrated to be effective and safe [ 21 ]. A multicenter, nonrandomized, open-label study of onabotulinumtoxinA treatment (50 IU per axilla) of bilaterally primary axillary HH in adolescents from 12 to 17 years old showed an improvement of 75% in 79.4–93.2% patients [ 22 ].…”
Section: Resultsmentioning
confidence: 99%
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“…In pediatric patients, HH affects 1.6% of adolescents and 0.6% of prepubertal children [ 20 ], and it remains widely undertreated. However, BoNT has been demonstrated to be effective and safe [ 21 ]. A multicenter, nonrandomized, open-label study of onabotulinumtoxinA treatment (50 IU per axilla) of bilaterally primary axillary HH in adolescents from 12 to 17 years old showed an improvement of 75% in 79.4–93.2% patients [ 22 ].…”
Section: Resultsmentioning
confidence: 99%
“…Pain can limit this treatment; thus several strategies have been evaluated to increase the compliance. Among these, ice with pressure, ice <20 or >20 seconds associated or not with topical anesthesia [ 23 , 24 ], general anesthesia, nerve blocks, vibration, pressure [ 21 ], and needle-free injections (Med-Jet MBX, Medical International Technologies, Montreal, QC, Canada) [ 25 ]. However, an open-label prospective study involving 20 patients with palmar HH, treated with needle injection on the right hand and with a needle-free device, has proven the efficacy of the device to be lower as compared to the classic needle injection [ 25 ].…”
Section: Resultsmentioning
confidence: 99%
“…Idiopathic hyperhidrosis (IH) is defined as perspiration in excess of the physiologic amount necessary to maintain thermal homeostasis. The prevalence of IP is underestimated by the currently reported figures, this due to underreported claims by patients and under-diagnosed by physicians, especially in the paediatric population, which is estimated to be around 1.6% [1]. This condition affects seriously the patients quality of life and self-esteem.…”
Section: Introductionmentioning
confidence: 94%
“…A number of treatments for hyperhidrosis exist, including topical antiperspirants, iontophoresis, intradermal botulinum toxin injections, systemic treatments, and surgical treatments such as focal curettage or liposuction of sweat gland-containing adipose tissue [68]. Newer prescription cloths embedded with glycopyrronium, an anticholinergic medication, are now available as well [69], offering a less invasive treatment option.…”
Section: Treatmentmentioning
confidence: 99%