Composite polysaccharide fibers prepared by electrospinning and coating

Maeda, Noriko; Miao, Jianjun; Simmons, Trevor J.; Dordick, Jonathan S.; Linhardt, Robert J.

doi:10.1016/j.carbpol.2013.10.038

Cited by 47 publications

(34 citation statements)

References 18 publications

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“…Cytotoxocity tests showed that CS/PLA/TX-15 nanofiber mats were safe and nontoxic toward Human Mesenchymal Stem Cells (hMSCs) [15]. Composite polysaccharide nanofibers containing chitosan and hyaluronic acid was prepared by electrospinning and characterized by Maeda et al [16] which found applications in wound healing and drug delivery. The first reported study on extra cellular polymeric substance of cyanobacterial origin (EPS) and PVA blend nanofibers embedded onto a poly vinyl fluoride (PVDF) membrane is studied for the application in water filtration [17].…”

Section: Methods Of Nano-fabrication Electrospinningmentioning

confidence: 99%

Biomedical Applications of Natural Polymer Based Nanofibrous Scaffolds

Preethi¹

2015

Int J Med Nano Res

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Nanotechnology is one of the most popular branches of science in the current decade where nanofiber scaffolds (NS) attain principal attraction. NS are composed of several nanometer to micrometer diameter fibers similar in nature to collagen, keratin and elastin fibers of the extracellular matrix (ECM) and helps in cell attachment, proliferation and differentiation. NS with desired features can be fabricated using various chemical, physical and biological methods such as electrospinning, phase separation, self-assembly, templating etc. Most often NS are fabricated using ECM derived compounds, naturally occurring polysaccharides such as chitosan, pullulan, dextran and many other synthetic compounds. Like ECM in natural niche NS interacts with cells and hence holds wide applications in Tissue engineering (TE)/ regenerative medicine where they are used as replacement for nerve, blood vessels, skin, muscle, bone and cartilage. They have also established applications in wound healing, drug testing and drug/ growth factor/ gene delivery. Application of cell free scaffolds for the culture of stem cells isolated from individual persons could pave way towards personalised therapy using TE. Cancer cells cultured in 3D microenvironment created with NS were observed to enhance the epithelial to mesenchymal transition. The present review principally focuses on various fabrication techniques and the application of various natural and synthetic compounds in tissue engineering.

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Section: Methods Of Nano-fabrication Electrospinningmentioning

confidence: 99%

Biomedical Applications of Natural Polymer Based Nanofibrous Scaffolds

Preethi¹

2015

Int J Med Nano Res

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“…Layer-by-layer coating hyaluronic acid dispersed CNTs, followed by an enzyme layer and a final Nafion layer affords electrodes for mediatorless NADH biosensing [38]. After electrospinning chitosan/poly(ethylene oxide) blends, the resulting fibers can be immersed in a hyaluronic acid solution to electrostatically coat the fibers with a layer of hyaluronan [39]. This simple method is effective in forming polyanion/polycation complexes.…”

Section: Composite Formationmentioning

confidence: 99%

Polysaccharide-based nanocomposites and their applications

Zheng

Monty

Linhardt

2015

Carbohydrate Research

199

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Polysaccharide nanocomposites have become increasingly important materials over the past decade. Polysaccharides offer a green alternative to synthetic polymers in the preparation of soft nanomaterials. They have also been used in composites with hard nanomaterials, such as metal nanoparticles and carbon-based nanomaterials. This mini review describes methods for polysaccharide nanocomposite preparation and reviews the various types and diverse applications for these novel materials.

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“…Young modulus was improved from 0.29±0.04 to 0.65±0.02 MPa by crosslinking. Maeda et al [191] electrospun chitosan with the aid of PEO, followed by coating with hyaluronic acid. The composite was made by dissolving PEO in water and coating with hyaluronic acid, and it was stable in water with an improved swelling ratio due to the increased hydrophilicity as a result of the presence of hyaluronic acid.…”

Section: Chitosanmentioning

confidence: 99%

A review on electrospun bio-based polymers for water treatment

Mokhena¹,

Jacobs²,

Luyt³

2015

Express Polym. Lett.

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Abstract. Over the past decades, electrospinning of biopolymers down to nanoscale garnered much interest to address most of the millennia issues related to water treatment. The fabrication of these nanostructured membranes added a new dimension to the current nanotechnologies where a wide range of materials can be processed to their nanosize. Electrospinning is a simple and versatile technique to fabricate unique nanostructured membranes with fascinating properties for a wide spectrum of applications such as filtration and others. These nanostructured membranes, fabricated by electrospinning, were found to be of a paramount importance because of their advanced inherited properties such as large surface-to-volume ratio, as well as tuneable porosity, stability, and high permeability. The extensive research conducted on these materials extended the success of electrospinning not only to bio-based polymer nanofibres, but to their hybrids and their derivatives. The technique also created avenues for advanced and massive production of nanofibres. This paper reviews the recent developments in the electrospinning technique. Electrospinning of biopolymers, their blends and functionalization using metals/metal oxides, and the potential applications of electrospun nanofibrous membranes in water filtration are discussed.

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Composite polysaccharide fibers prepared by electrospinning and coating

Cited by 47 publications

References 18 publications

Biomedical Applications of Natural Polymer Based Nanofibrous Scaffolds

Biomedical Applications of Natural Polymer Based Nanofibrous Scaffolds

Polysaccharide-based nanocomposites and their applications

A review on electrospun bio-based polymers for water treatment

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