Depression, deficits in functional capacity, and impaired glycemic control in urban African Americans with type 2 diabetes

Musselman, Dominique L.; Ziemer, David C.; McNutt, Marcia D.; Seay, Julia; Royster, Erica; Larsen, Bridget; Barham, Terrika; Brown, Angelo R.; Vogel, Octavia L.; Phillips, Lawrence S.; Harvey, Philip D.

doi:10.1016/j.jpsychires.2014.01.006

Cited by 22 publications

(22 citation statements)

References 58 publications

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“…While previous research has found hypertension, high triglycerides, depression, and insulin use to be associated with inadequate glycemic control [21,29], our findings suggest that additional research using a syndemic framework is needed to explore the interrelationships between these and other co-occurring health challenges. In our study population of HIV-infected MSM attending an urban community health center, we found that current substance abuse and detectable HIV viral load were independently associated with inadequate glycemic control.…”

Section: Discussioncontrasting

confidence: 57%

“…A syndemic framework may be useful in understanding the management of diabetes in this population because these co-occurring conditions may synergistically affect glycemic control [20][21][22][23]. For MSM with HIV, management of comorbid chronic conditions such as diabetes may prove particularly challenging due to increased HIV-associated risks of lipodystrophy, coronary artery disease, and chronic kidney disease, which make glycemic control harder to achieve [24].…”

Section: Introductionmentioning

confidence: 99%

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The Utility of a Syndemic Framework in Understanding Chronic Disease Management Among HIV-Infected and Type 2 Diabetic Men Who Have Sex with Men

et al. 2016

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Syndemic theory posits that epidemics of multiple physical and psychosocial problems co-occur among disadvantaged groups due to adverse social conditions. Although sexual minority populations are often stigmatized and vulnerable to multiple health problems, the syndemic perspective has been underutilized in understanding chronic disease. To assess the potential utility of this perspective in understanding the management of co-occurring HIV and Type 2 diabetes, we used linear regression to examine glycemic control (A1c) among men who have sex with men (MSM) with both HIV and Type 2 diabetes (n = 88). Bivariable linear regression explored potential syndemic correlates of inadequate glycemic control. Compared to those with adequate glycemic control (A1c ≤ 7.5 %), more men with inadequate glycemic control (A1c > 7.5 %) had hypertension (70 vs. 46 %, p = 0.034), high triglycerides (93 vs. 61 %, p = 0.002), depression (67 vs. 39 %, p = 0.018), current substance abuse (15 vs. 2 %, p = 0.014), and detectable levels of HIV (i.e., viral load ≥75 copies per ml blood; 30 vs. 10 %, p = 0.019). In multivariable regression controlling for age, the factors that were independently associated with higher A1c were high triglycerides, substance use, and detectable HIV viral load, suggesting that chronic disease management among MSM is complex and challenging for patients and providers. Findings also suggest that syndemic theory can be a clarifying lens for understanding chronic disease management among sexual minority stigmatized populations. Interventions targeting single conditions may be inadequate when multiple conditions co-occur; thus, research using a syndemic framework may be helpful in identifying intervention strategies that target multiple co-occurring conditions.

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Section: Discussioncontrasting

confidence: 57%

Section: Introductionmentioning

confidence: 99%

The Utility of a Syndemic Framework in Understanding Chronic Disease Management Among HIV-Infected and Type 2 Diabetic Men Who Have Sex with Men

et al. 2016

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“…(Hilliard et al 2011) Five studies, conducted in Germany, The Netherlands and the USA, including a total of 20661 participants, looking at management of Type 2 Diabetes, were identified (Supplement 6). (Richardson et al 2008, Heckbert et al 2010, Bot et al 2013, Kostev et al 2016, Musselman et al 2014) Follow up ranged between three months and ten years. In one study 97% of participants were men.…”

Section: Smokingmentioning

confidence: 99%

Disparities in the management of cardiovascular risk factors in patients with psychiatric disorders: a systematic review and meta-analysis

et al. 2018

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“…Approximately 20–30% of patients with diabetes suffered from depressive disorders, which was more common than among the general population [2,3]. Meanwhile, depression was found to be associated with the increased risk of diabetes mellitus [4] and higher risk of complications and adverse outcomes in patients with diabetes mellitus [5,6]. Moreover, treatment non-adherence caused by depression [7] could result in poorer self-care behaviour [8,9].…”

Section: Introductionmentioning

confidence: 99%

Cognitive behavioural therapy on improving the depression symptoms in patients with diabetes: a meta-analysis of randomized control trials

et al. 2017

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This meta-analysis was performed to evaluate the effect of cognitive behavioural therapy (CBT) in improving the depression symptoms of patients with diabetes. Literature search was conducted in PubMed and Embase up to October 2016 without the initial date. The pooled SMD (standard mean difference) and its 95% confidence interval (CI) were calculated by Revman 5.3. Subgroup analyses were performed by type of diabetes and evaluation criteria of depression. A total of five randomized control trials involving 834 patients with diabetes mellitus (including 417 patients in CBT group and 417 patients in control group) were included in this meta-analysis. The pooled estimates indicated significant improvement of depression by CBT compared with routine approaches in overall outcomes (SMD =–0.33, 95% CI =–0.46 to –0.21, P<0.00001), post-intervention outcomes (SMD =–0.43, 95% CI =–0.73 to –0.12, P=0.006) and outcomes after 12 months intervention (SMD =–0.38, 95% CI = –0.54 to –0.23, P<0.0001). Subgroup analyses showed that the results were not influenced by the type of diabetes. However, the effect of CBT on improving the depression symptoms disappeared when only using CES-D (Centre for Epidemiological Studies scale for Depression) to evaluate depression.

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Depression, deficits in functional capacity, and impaired glycemic control in urban African Americans with type 2 diabetes

Cited by 22 publications

References 58 publications

The Utility of a Syndemic Framework in Understanding Chronic Disease Management Among HIV-Infected and Type 2 Diabetic Men Who Have Sex with Men

The Utility of a Syndemic Framework in Understanding Chronic Disease Management Among HIV-Infected and Type 2 Diabetic Men Who Have Sex with Men

Disparities in the management of cardiovascular risk factors in patients with psychiatric disorders: a systematic review and meta-analysis

Cognitive behavioural therapy on improving the depression symptoms in patients with diabetes: a meta-analysis of randomized control trials

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