A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department

Jenkins, Mark; Murphy, Diarmaid J.; Little, Carol; McDonald, Julie; McCarron, Paul A.

doi:10.1016/j.annemergmed.2013.12.012

Cited by 10 publications

(5 citation statements)

References 20 publications

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“…Evidence suggests that topical application is at least as effective as injection of local anesthesia in patients with lacerations (Jenkins, Murphy, Little, McDonald, & McCarron, 2014). A lidocaine emulsion formulation and an aqueous solution were equally effective at reducing pain during dressing changes in a double-blind trial of burn patients (Desai et al, 2014).…”

Section: Resultsmentioning

confidence: 99%

Exploring Opioid-Sparing Multimodal Analgesia Options in Trauma: A Nursing Perspective

Sullivan

Lyons

Montgomery

et al. 2016

Journal of Trauma Nursing

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Section: Resultsmentioning

confidence: 99%

Exploring Opioid-Sparing Multimodal Analgesia Options in Trauma: A Nursing Perspective

Sullivan

Lyons

Montgomery

et al. 2016

Journal of Trauma Nursing

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“…Dehiscence rates have been more variable and dependent on both the patient population and the method used to define this outcome. Nevertheless, dehiscence typically occurs at a rate ≤15% 10,19–21 . Although lacerations repaired by the nurse practitioners had the highest rate of dehiscence, this group also repaired the highest proportion of wounds affecting the hand.…”

Section: Discussionmentioning

confidence: 95%

“…Nevertheless, dehiscence typically occurs at a rate ≤15%. 10,[19][20][21] Although lacerations repaired by the nurse practitioners had the highest rate of dehiscence, this group also repaired the highest proportion of wounds affecting the hand. Although conjecture, lacerations repairs at this site may be more prone to stress and, therefore, dehiscence.…”

Section: Discussionmentioning

confidence: 96%

Outcomes of laceration suture repair in the emergency department

Majer

Valentine

Warren

et al. 2020

Emerg Medicine Australasia

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Objective To assess patient satisfaction with laceration management, post‐ED care, cosmesis and complication rates. Methods We undertook a prospective observational study of adult patients with lacerations sutured in two EDs over a 4‐month period. ED data included participant demographics, laceration characteristics and management. A telephone survey was undertaken approximately 14 days post‐ED discharge. Patient satisfaction with post‐ED pain management, advice on wound care and follow up, overall management and wound cosmesis were evaluated using a six‐item satisfaction scale (very dissatisfied to very satisfied). Details of wound infection, dehiscence and suture failure were recorded. Results Eighty‐nine patients participated. The number (% [95% confidence interval]) of patients very satisfied with their laceration management were: post‐ED pain management 55 (62.5% [51.5–72.4]), wound care advice 51 (57.3% [46.4–67.6]), follow‐up advice 39 (43.8% [33.5–54.7]), overall management 61 (68.5% [57.7–77.7]) and cosmetic appearance 46 (51.7% [40.9–62.3]). Infection, dehiscence and suture failure occurred in 5 (5.6%), 8 (9.0%) and 8 (9.0%) cases, respectively. These complications were not associated with being very satisfied overall (P = 0.96). Patients very satisfied with post‐ED pain management, wound care advice, follow‐up advice or wound cosmesis were much more likely to be very satisfied overall (P < 0.001). Conclusions Most patients are very satisfied with their laceration management. However, there is scope for improvement, especially for follow‐up and wound care advice. Complications are infrequent and not associated with overall satisfaction.

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“…Wound inflammation was seen in only one patient who had drug injection. 7 In another study, pain ensuing from arterial blood gas sampling was significantly lower in patients who had jet injection of 2 ml of 2% lidocaine compared with those in whom topical lidocaine was applied (p<0.001). Pain was evaluated using visual analogue scale score.…”

Section: Injection Versus Topicalmentioning

confidence: 91%

Use of Lidocaine for Pain Management in the Emergency Medicine: A Systematic Review and Meta-Analysis

et al. 2019

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Background: Lidocaine is a well-known medium-acting local anesthetic with a short onset time. It is a valuable drug for managing both acute and chronic pains and is being used as a popular agent for pain control in the emergency department (ED). In this systematic review, we intended to define the effectiveness of lidocaine in pain management of the patients referring to ED. Methods: The preferred reporting items for systematic reviews and meta-analysis (PRISMA) statement was utilized for this Systematic Review (SR). We searched the databases of PubMed, Scopus, ProQuest, and Medline (Ovid) from 1990 to August 2017 for Randomized Controlled Trials (RCTs) in which the study population was referred to the emergency department and received lidocaine. Full-texts of the studies that were published in English were reviewed for inclusion. Both authors individualistically evaluated all studies. Seven articles were eligible for the meta-analysis based on their common outcomes. Results: The total number of subjects was 671. The studies were categorized based on the type of drug and administration route. Mean pain, regardless of the drug administration method, in the placebo group was 0.69 units higher than the lidocaine group. Considering the administration route, mean pain in the placebo group was 0.35 units higher than the lidocaine group when administered topically, and it was lower in the subcutaneous method than the topical method by 1.41 units. Conclusion: Infiltration of lidocaine decreases pain of different procedures in the ED whereas the effect of topical lidocaine is controversial issue.

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A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department

Cited by 10 publications

References 20 publications

Exploring Opioid-Sparing Multimodal Analgesia Options in Trauma: A Nursing Perspective

Exploring Opioid-Sparing Multimodal Analgesia Options in Trauma: A Nursing Perspective

Outcomes of laceration suture repair in the emergency department

Use of Lidocaine for Pain Management in the Emergency Medicine: A Systematic Review and Meta-Analysis

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